M.B. O'Neill

Population geneticist interested in evolutionary consequences of infectious disease for both hosts and pathogens, and everything single-cell!

[M.B. O'Neill @ONeillMB1]

Just made a #BlueSky account. Don't find myself using #sciencetwitter these days.

[Brotman Baty @BrotmanBaty]

New @Nature paper states @IGVFConsortium 'will drive scientific discoveries in human health and disease for years to come.' Authors include BBI's @lea_starita
@varianteffects @uwgenome @UWMedicine
https://t.co/XHhfb6kqWh

[M.B. O'Neill @ONeillMB1]

Save the date for the next Seattle Area Single Cell (SASC, "sassy") user group meeting, September 27th at UW SLU campus! https://t.co/unwTJGTswm

[Nobu Hamazaki @Nobu_Hamazaki]

Excited to share our human RA-gastruloid model in @NatureCellBio! Early retinoic acid supplementation, followed by later Matrigel addition, robustly induces human embryonic morphologies and diverse cell lineages, including somitic, renal, cardiac, and neural cell types in #gastruloid. https://t.co/buaAcqxGlZ

[Sanjay Srivatsan @SRsrivatsan]

Today out in @biorxivpreprint we present SCOPE. An optics-free, self-registering array of DNA encoded beads for spatial genomics. This was work led by the intrepid duo of Hanna Liao and Sanjay Kottapalli, with @JShendure's lab. https://t.co/ovGaBmQB1V

[Jay Shendure @JShendure]

Our latest, from the brilliant @wchenomics and @_Choi_Junhong, out in @Nature , is ENGRAM, a multiplex method for symbolic recording of signaling and cis regulatory activity to DNA. Final version (not in preprint) includes integration w/ DNA Typewriter. https://t.co/XmiIZSNWpv

[Brotman Baty @BrotmanBaty]

Working under BBI’s Danny Miller's direction, 3 PhD students are using Long-Read Sequencing to help seek ‘an end to the diagnostic odyssey for individuals and their families.’
@nanopore @UWMedicine
https://t.co/JEupBg1bdO

[M.B. O'Neill @ONeillMB1]

Anyone else experiencing this?

[M.B. O'Neill @ONeillMB1]

Thank you @satijalab for organizing another great #singlecellgenomicsday. As of a couple of minutes ago, the stream has turned private?

[Rahul Satija @satijalab]

Beautiful new work from @N_Rajewsky lab on DIY high-resolution and 3D spatial transcriptomics. Learn more at https://t.co/E9Oi7ZGXVC

[Rahul Satija @satijalab]

Want to hear about the latest updates/new techniques in single cell and spatial genomics? Check out the full agenda for our Single Cell Genomics Day on Friday, 3/29. All talks will be live-streamed (no registration required) at https://t.co/KJpeGwWLIr

[Nobu Hamazaki @Nobu_Hamazaki]

We (with @VinetteY and @JShendure) are thrilled to announce our new paper on the "human RA-gastruloid" model, showcasing morphologies and transcriptomes akin to E9.5 (mouse) or CS10-11 embryos (https://t.co/vBZYmtEdB9). (1/n)

[Brotman Baty @BrotmanBaty]

ATTENTION SINGLE‐CELL RESEARCHERS: BBI is organizing a Seattle area Single Cell User Group to share knowledge & insights. Please complete this survey (https://t.co/H5CtL9qz2a) by (12/26/23), then watch for details.
https://t.co/dALeGsRuUi

[biohub @biohub]

Join us in celebrating the launch of the Seattle Hub for Synthetic Biology with @AllenInstitute + @UWMedicine. 🎉 Led by @JShendure, this new collaboration will build tech to understand temporal dynamics of cells & whole organism perturbation ➡️ https://t.co/JbPIrkcKNO #SeaSynBio

[M.B. O'Neill @ONeillMB1]

@skrabadlo @lpachter @sinabooeshaghi @IngileifBryndis @agalvezmerchan Was wondering the same!

[Sanjay Srivatsan @SRsrivatsan]

Thrilled to announce the opening of the Srivatsan Lab (https://t.co/mUPc2wHm0X) at the @fredhutch. The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.

[Noah Snyder-Mackler @SMack_Lab]

Chuffed to be part of this package of papers mapping/understanding the human & nonhuman primate brain.

Big ups to coauthors–especially @kchiou @XingfanH who led the effort & co-leaders @JShendure @MichaelLouisPl1

Excited to see what is next!

@BrotmanBaty @asuSOLS @evmedasu

[Sudarshan Pinglay @sudpinglay]

Happy to share that I am starting my own research group @BrotmanBaty and @uwgenome with an early independence award from @NIH_CommonFund #NIHHighRisk

[Institut Pasteur Education @PasteurEdu]

What was the migration history of our species? What role does the Neanderthal genome play in our current genetic heritage?
Discover the answers from genetics in the online course "HPEG".

https://t.co/wwKX4WTgVu
@FunMooc @institutpasteur @QuintanaMurci @Etienne_Patin

[M.B. O'Neill @ONeillMB1]

Thrilled to have worked on this project with such an amazing and adaptive team! Congrats to all, especially @aquino_yann @MonsieurRoti @QuintanaMurci for seeing this across the finish line!

[nature @Nature]

Nature research paper: Dissecting human population variation in single-cell responses to SARS-CoV-2 https://t.co/Vp7e9XEmUQ