Open-ST

Open-Source Spatial Transcriptomics developed in the @N_Rajewsky lab, @MDC_Berlin

[Open-ST @open_sts]

🤝 Join the Open-ST community!

• Use our example data to test the pipeline
• Check our troubleshooting guide
• Share your experience
• Get support from other users

Open science in action! 🌟

[Open-ST @open_sts]

🧬 Want to implement Open-ST in your lab?

We've published a detailed guide that takes you from tissue sections to 3D molecular maps

https://t.co/IrpTFnnoe9

[Open-ST @open_sts]

💡 The protocol includes:

• Detailed experimental procedures
• Complete computational pipeline
• Quality control guidelines
• Example datasets to test your setup
• Interactive 3D visualization

🔗 All resources available at: https://t.co/r8pWAhjQry

[Cell @CellCellPress]

In the latest issue! Open-ST: High-resolution spatial transcriptomics in 3D https://t.co/WkuaiZh9Rz

[Max Delbrück Center @MDC_Berlin]

The @N_Rajewsky lab at the #mdcBerlin has developed a spatial transcriptomics platform to reconstruct tissues in #3D with subcellular resolution. The platform will enable a deeper understanding of basic biology and of how diseases develop:
https://t.co/aUBVF8KI0O @CellCellPress

[Nikolaus Rajewsky @N_Rajewsky]

i am so excited about our open source inexpensive, sub-cellular capture, do-it-yourself Open-ST that transforms tissues into virtual tissue blocks in 3D - IDing pathways & gene programs driving phenotypes. a huge congratz to the team! https://t.co/UvyBdFGZRX

[Nikos Karaiskos @nu_karaiskos]

And it's out 🎉

Check out our updated paper & tweetorial on Open-ST, our DIY spatial transcriptomics method.

Many, many thanks to everyone involved in this huge & exciting project!

#OpenST #SpatialTranscriptomics

[Ivano Legnini @ILegnini]

Terrific work, huge congrats Marie, Daniel, Elena, Pino, Nikos, Nikolaus and everyone involved!! Likely a game changer for many labs doing spatial omics 🚀🚀🚀

[Daniel León-Periñán @danilexn]

Our #OpenST paper is now online @CellCellPress!

https://t.co/ThNLdnhQpF

Very cool updates ahead🧵⬇️

@L_Marie_Schott @_Elena_93 #GiuseppeMacino @nu_karaiskos @N_Rajewsky

[Daniel León-Periñán @danilexn]

A spatial transcriptomics method that…

🧪is easy to use
🔬has high resolution
🪙is cost-efficient
🌍scales to 3D

Just in time for Xmas:
Open-ST, a end-to-end, open-source method that checks all boxes, from the @N_Rajewsky lab

📄Preprint: https://t.co/DJmkJSlCKH

🧵⬇️