Olaf Perdijk

Assistant Professor of Mucosal Immunology. Focussed on interplay of gut microbiome and host metabolism and immunity.

[NRC @nrc]

Hoe poeppillen mogelijk een pinda-allergie verhelpen https://t.co/i6ErWF87kJ

[Cell Reports @CellReports]

Microbial imprinting of the airway epithelium https://t.co/0PnTHuh1CK

[Society for Mucosal Immunology @socmucimm]

Read the latest #SMIMemberPaper from @BenJMarsland and colleagues in @ImmunityCP on how early life #Antiboitics reduce systemic indole-3-propionic acid levels required to maintain mitochondrial respiration in the lung. https://t.co/muD4cucaYz

[Immunity @ImmunityCP]

Hit me baby one more time…with microbial IPA https://t.co/uh712QMMNI

[Cell Press @CellPressNews]

‘@cellhostmicrobe special issue illustrates how microbial composition of specific tissues and organs systemically contributes to maintenance of homeostasis (health) or drives disease development and progression. Take a look. https://t.co/xCfXPKCU1a

[Immunity @ImmunityCP]

Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood https://t.co/zECRY6ELmh

[Biocodex Microbiota Institute @Microbiota_Inst]

"Antibiotic-driven #dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood," concludes a study in @ImmunityCP.

@OPerdijk

#microbiota👇
https://t.co/bX0TVFRY58

[Olaf Perdijk @OPerdijk]

I am very grateful to @NatRevImmunol for highlighting our recent publication! Special thanks to Lucy Bird for doing a fantastic job in summarizing our findings in such detailed yet concise way. https://t.co/S9MwSwyi8H

[Nature Rev Immunol @NatRevImmunol]

Early life antibiotics have lasting effects on the lung epithelium https://t.co/u54K0iC8SF

[Petter Brodin @BrodinPetter]

Systems immunology is not only immunology with more data. It is a new way of thinking about immune systems as integrated multiagent systems w particular value for making variable human immune system more interpretable: https://t.co/qPFWAMqHKn

[Lauren Howson @lauren_jtweets]

📚 Just published a BCR repertoire sequencing protocol! This is the result of a great collaboration with Prasanti Kotagiri, Rachael Bashford-Rogers and @vanessabryantoz. Thanks to editor @KimLJacobson for the opportunity! https://t.co/QwvwzDLF3O

[Eric Topol @EricTopol]

Proteins, proteins, proteins.
How 3,000 blood proteins can help predict 10-year risk of >200 common and rare diseases, beyond genomic markers
https://t.co/4HdgIRigXt
@uk_biobank @NatureMedicine

[Translational Medicine at Monash University @MonashSTM]

Media coverage continues on research led by @BenJMarsland and @OPerdijk on #asthma and antibiotic use in infancy, centring on the molecule IPA.
https://t.co/3jfptBAguz

[7NEWS Melbourne @7NewsMelbourne]

Melbourne researchers have unlocked why children are more likely to develop asthma after early exposure to antibiotics. Professor Ben Marsland speaks to @mikeamor7 about the research. https://t.co/5zYfOfGqUb #7NEWS

[𝙵𝚛𝚘𝚗𝚝 𝙿𝚊𝚐𝚎𝚜 𝚃𝚘𝚍𝚊𝚢 📰 @ukpapers]

🇦🇺 Asthma Breakthrough

▫It’s one of asthma’s biggest causes and can begin in babies, but doctors did not know why – and therefore how to prevent it – until now
▫@sarahbooth_14

#frontpagestoday #Australia @theheraldsun 🇦🇺

[Translational Medicine at Monash University @MonashSTM]

Viruses, OTT cleanliness, genetics … all these have been linked to a higher chance of having #asthma.

Now, @Benjmarsland has led research isolated the molecule IPA: when subjected to antibiotic onslaught, IPA disappears from the airways, taking with it valuable protection against asthma.

Here’s Ben being interviewed in the lab with reporters from @7NewsMelbourne and @10NewsFirstMelb

[Waggoner Lab @LabWaggoner]

Microbiome derived indole-3-propionic acid prevents long-lasting mitochondrial damage in airway epithelial cells & hyperresponsiveness to allergen challenge, reducing allergic inflammation in adulthood @ImmunityCP @BenJMarsland @TomaszWypych8 @OPerdijk
https://t.co/vb29Yud2ZC

[Olaf Perdijk @OPerdijk]

#GutMicrobiome #Metabolomics #Antibiotics #CellMetabolism #AllergyResearch #ImmunityJournal #CellPress #MicrobiomeResearch #Immunology

[Olaf Perdijk @OPerdijk]

Incredibly proud to showcase our work published today in @ImmunityCP!
Our findings reveal that the early-life gut microbiota produces metabolites with the potential to prime the airway epithelium and prevent allergic inflammation in adulthood. https://t.co/z2bq9au5J0

[Immunity @ImmunityCP]

Online now: Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood https://t.co/YKMa9bhKDF