Olga Nyssen

[AIDA EU project @AIDAeuproject]

Did you know? Smoking increases the risk of gastric cancer and precancerous stomach lesions.
Prevention and awareness matter. At AIDA, we work to improve early detection and gastric cancer prevention through research and AI.

[Olga Nyssen @opnyssen]

@oriolciurana Vamos Uriiii😀que bueno verte!!

[Olga Nyssen @opnyssen]

I'm delighted to share the success of the article on adherence from the @hpeureg published at @UEGJournal and among the top 10 most-cited papers published by the Journal in 2024. This achievement highlights the impact of this work within the community, Congratulations to all!

[AIDA EU project @AIDAeuproject]

💭"In Spain, we have moved to quadruple therapies, a shift associated with an increase in global efficacy from 83.5% to 97%."

During the AIDA Webinar Series, Javier Tejedor from University Hospital of Cabueñes gave us a glimpse into new data.

Ask for a link to the webinar!

[Hp-EuReg 💊 @hpeureg]

📢 Website update!

We’ve made several improvements to our site, and we’re excited to share them with you. All information is now clearly divided into two sections: HpEuReg🇪🇺 and WorldHpReg🗺️.

🚀 Visit the site to learn more!

🔗 https://t.co/tXltOZFi9r

[AIDA EU project @AIDAeuproject]

A previous version of this post included an error. The correct number is 38,000.

[Hp-EuReg 💊 @hpeureg]

🦠 H. pylori follow-up gap in Europe

📊 European registry study:
❗ 14% of patients not retreated after eradication failure.
👤 Mostly patient-driven decisions.
⚠️ Barriers: poor adherence, multiple failures, older age.

🔗https://t.co/dOqRwoUt6T

[Olga Nyssen @opnyssen]

11th February - International Day of Women and Girls in Science!
Thank you @AIDAeuproject for choosing me as your representative today, I'm overwhelmed, honoured and very proud to share with inspiring women in this project against gastric cancer.

[AIDA EU project @AIDAeuproject]

🌍 Today we celebrate women shaping the future of science 💜
“As part of AIDA, I see how women lead, innovate, and transform health through teamwork and support.” – Olga P. Nyssen
#womeninscience

[Hp-EuReg 💊 @hpeureg]

🦠💊 Macrolides & H. pylori
📉 Prior macrolide use = lower eradication success
⏳ Strongest effect in the last 2–4 years
🌍 Data from 27k+ patients, 23 countries
➡️ Clear impact of antibiotic pressure on outcomes

🔗https://t.co/InmgxEBpaW

[AIDA EU project @AIDAeuproject]

🔎How is the AIDA AI-Clinician trained?

The AI-Clinician learns from real-world clinical experience captured in the @hpeureg registry.
Using reinforcement learning, the AI trains like a physician, gaining experience. Ultimately, it recommends personalised first-line therapies.

[Hp-EuReg 💊 @hpeureg]

🧪 Non-Bismuth Concomitant Therapy for H. pylori
Meta-analysis (144 studies; >26k pts):

🔹 Eradication: 86% ITT / 91% PP
🔹 Better than triple & sequential therapy
🔹 Similar to bismuth & hybrid regimens
⚠️ Lower efficacy with dual resistance (~67%)
📄 https://t.co/zs5kwvGMir

[Hp-EuReg 💊 @hpeureg]

Treating the H. pylori stomach bacteria significantly lowers the risk of developing gastric cancer. 📉

A major new study confirms that screening and treating this infection is a powerful way to prevent cancer. 💊🦠

🔗https://t.co/P6q99Jb1Bn

@GastroJournalGJ

[Hp-EuReg 💊 @hpeureg]

🔎Over 2/3 of new gastric cancer cases are attributable to H. pylori. New global estimates from 27 countries:

~454,800 cases & ~287,800 deaths in 2022 linked to the infection.

🔗 https://t.co/UZd1dwiaTj

@SpringerNature

[Hp-EuReg 💊 @hpeureg]

Mass screening & eradication of Helicobacter pylori can prevent gastric cancer.
Temporary gut microbiota changes recover within 6–12 months. Promising step for public health!

🔗 Read more: [https://t.co/nGIW4sGBvu] @Gut_BMJ

[Hp-EuReg 💊 @hpeureg]

The final paginated version of our study on probiotics in Helicobacter pylori eradication is now available! 🦠

🔗Read it in The American Journal of Gastroenterology: https://t.co/sgnTFn7nj0

Preprint (Feb): https://t.co/SFMlgdZBg9

[Hp-EuReg 💊 @hpeureg]

At#SVPD2025, 🇪🇸 Samuel J. Martínez-Domínguez shared key lessons from Hp-EuReg to improve H. pylori management: avoid OCA where ineffective, 7-day regimens, low PPI doses, repeated antibiotics, and unconfirmed eradication. 👏 @samu_martiinez @JoseMHuguet2

[Hp-EuReg 💊 @hpeureg]

🇧🇷 New data from >500 H. pylori retreatments:

🔹 2nd-line success: 74%
🔹 14-day regimens + bismuth/vonoprazan → up to 100% eradication
🔹 Mild AEs (23%), 99% adherence
💡 Optimized 14-day, bismuth/vonoprazan therapies excel in rescue management.

👉https://t.co/G4pqU851xY

[Hp-EuReg 💊 @hpeureg]

💻 Team vibes at #HpEureg!

Our regular online meetings sessions keep the energy up — sharing ideas, tackling challenges, and getting better every single day! 💪✨

Nothing beats teamwork! 🙌

[#EIILaPrincesa @EIILaPrincesa]

🚀 Éxito total en #UEGWeek2025: la Unidad de EII @EIILaPrincesa y el Hp-EuReg @hpeureg, coordinado desde el Hospital de La Princesa, han obtenido 6 premios 🥇🥇🥇🥇🥇🥇
Orgullosísimos de este equipazo y de todos los investigadores 👏👏@my_ueg @aegastro @geteccu