Bridget Ostrem, M.D., Ph.D.

The Ostrem Lab is focused on improving the treatment of neurological problems in the developing (fetal and neonatal) brain and in pregnancy.

[Noelia Antón-Bolaños @BolanosAnton]

📢Thrilled! My 1st piece of work of my postdoc at @Arlottalab is out @Nature! This has been a huge co-lead effort with @IreneFaravelli👩‍🔬👩‍🔬🤩
Link: https://t.co/9HmNVh0SQZ
Tweetorial 👇🧵

[Bridget Ostrem, M.D., Ph.D. @ostremlab]

Our paper investigating clemastine as a possible treatment for preterm brain injury is out! Congrats @Lenaodell07 and coauthors https://t.co/Vp1qvgiRNY

[Arlotta Lab @ArlottaLab]

Happy to share our latest work on microglia! We developed a comprehensive transcriptional atlas of microglia throughout cortical development and demonstrated that these cells are essential for cortical changes induced by in utero inflammation. Congratulations to all co-authors and collaborators @ostremlab, @NuriaIturza, @jeff_stogsdill, @FaitsTyler, @kwanho_k, @jzlevin !!! https://t.co/MJkiX0BBtL

[Harwell Lab @Harwell_Lab]

Please check our newest study on @biorxivpreprint - a tour de force led by the phenomenal @Chris_M_Reid, describing the diversity of neurons in the lateral septum in terms of transcriptomics, anatomical distribution, connectivity and electrophysiology: https://t.co/MQAtPvSBRH

[Bridget Ostrem, M.D., Ph.D. @ostremlab]

I am excited to share our recent work towards a new treatment for brain injury in premature babies. We identify the minimum effective dose and target blood levels of clemastine in neonatal mice. Congrats to Lena and co-authors @Lenaodell07 @NoraJabassini https://t.co/h8H22ePn3b

[Arlotta Lab @ArlottaLab]

We are happy to share our recent pre-print! We built a transcriptional atlas of microglia development and demonstrate that microglia are necessary for cortical gene expression changes triggered by in utero inflammation. Congratulations to all co-authors @ostremlab, @NuriaIturza, @jeff_stogsdill, @FaitsTyler, @kwanho_k,  @jzlevin!!! https://t.co/nVnxMZuLlK

[Arlotta Lab @ArlottaLab]

We are very happy to share our latest work published in @NatureNeuro today! 🧬🧠

https://t.co/yWVEY3wlNN

[Bridget Ostrem, M.D., Ph.D. @ostremlab]

We are hiring research technicians! If you are interested in neurology, neuroscience, and developing treatments for neonatal brain injury, reach out via DM! https://t.co/J44Kww8oGz

[Child Neurology Foundation @Child_Neurology]

The Child Neurology Foundation (CNF) and the Child Neurology Society (CNS) stand firm in our commitment that all have access to safe, equitable and quality healthcare, including medical termination of pregnancy - abortion.

Read our full statement here: https://t.co/JPShyfogrg

[Dena Dubal @DenaDubal]

Just out. Kdm6a is an X chromosome factor that is lower in males compared to females. We found that acutely increasing Kdm6a enhances memory independent of its demethylase function in the #aging XY male brain. @cayce_shaw @jusabdulsam https://t.co/BIcgtNWNPv

[Bob Wachter @Bob_Wachter]

Looking forward to appearing on @KQEDForum tomorrow 9am Pacific. Guests: me and Bonnie Maldonado @StanfordPeds.
We'll discuss BA.5, new boosters & booster rules, Paxlovid, kids, etc. Host @alexismadrigal. @KQED @NPR
https://t.co/x5ewTOpvL9

[Bridget Ostrem, M.D., Ph.D. @ostremlab]

Also wanted to highlight our recent publication, the result of an international collaboration between multiple MS centers. Higher disability increases the risk of relapses and disability progression after pregnancy in patients with MS. https://t.co/1EbAI8Y5ws

[Bridget Ostrem, M.D., Ph.D. @ostremlab]

I'm excited to announce that the Ostrem Lab has officially been established at UCSF! We are focused on improving treatments for neonatal brain injury, working in collaboration with Drs. Jonah Chan, Ari Green, and many other incredible scientists at UCSF.