Hemanta Pathak

Nothing Here, move on!

[Hemanta Pathak @pathak_hemanta]

#RandomTidBits
Bolo Yeung fights Bruce Lee, using Jackie Chan as a weapon, in Enter the Dragon 1973.

[ABHI @aksiiita06]

@advocate_alakh Nice Car.

And I know it comes from stretching a problem, not solving a problem.

Here is a real time report card of your institution.

[Ananth Rupanagudi @AnanthOnTrack]

An Indian scientist at Harvard discovered ATP (Adenosine Triphosphate). Then he helped create the first chemotherapy drug and the first tetracycline antibiotic. Harvard still refused him tenure. A bowling alley would not let him bowl. He died at 53, without an obituary.

His medicines save tens of millions of lives every year. Most American doctors who prescribe them have no idea what his name was. His name was Yellapragada Subbarow (Subba Rao).

He was born in 1895 in Bhimavaram, India. His father was a Sanskrit scholar who died from tropical sprue. Tropical sprue is an acquired malabsorptive disorder found in tropical regions, characterized by chronic diarrhea, weight loss, and severe nutritional deficiencies. It is most commonly associated with deficiencies in vitamin B12 and folic acid, resulting in anemia, fatigue, and glossitis. The same disease killed two of his brothers. As a child, Subbarow watched them fade away and decided he would spend his life fighting disease.

He failed his school exams twice. Passed on the third attempt. His future father-in-law paid for his medical school books. Subbarow married his daughter and repaid the debt. In October 1922, he arrived in Boston with borrowed money and broken English. He was 27. He entered Harvard Medical School and joined the biochemistry PhD program.

He began working under a senior researcher named Cyrus Fiske. Long hours. Little pay. But he was at Harvard, and he did not care. In 1925, they developed the Fiske-SubbaRow assay, a method for measuring phosphorus in body fluids. It is still used today in kidney failure testing, vitamin D testing, and prostate cancer work. It became one of the most cited methods in biochemistry history.

Then they found something even bigger in 1926 - ATP - Adenosine triphosphate. The energy molecule that powers every cell in every living thing on Earth. That discovery changed biochemistry. It also proved that the 1922 Nobel laureate had been wrong about how muscles worked. Muscles did not run on glycogen. They ran on ATP.

Subbarow earned his PhD in 1930. He stayed at Harvard for another decade. Paper after paper. Discovery after discovery. And every year, Harvard refused to promote him. The biochemistry department had never given tenure to a foreigner. They were not going to begin with an Indian.

His colleagues took him fishing. Played tennis with him. Came to dinner at his home. Then voted against him year after year. Outside the laboratory, he met the same wall. He bought an airplane and learned to fly because he loved flying. Once, he tried to go bowling. The local alley refused him entry. The sign said it was “open only to the Caucasian race.”

Then Fiske turned against him. The senior researcher began blocking Subbarow’s discoveries out of jealousy. Some of Subbarow’s work had to be rediscovered years later by other scientists because Fiske kept his findings hidden.

May 1940. Harvard denied him tenure for the last time. After 17 years of groundbreaking work, he walked away. Lederle Laboratories in New York hired him as Associate Director of Research. By the end of the year, he was Director. In the next eight years, he changed medicine. He developed diethylcarbamazine, an oral medicine that killed the tropical worms crippling American soldiers in the Pacific. The World Health Organization still uses it.

He isolated folic acid from liver and worked out how to produce it on a large scale. Today, folic acid in pregnancy prevents birth defects in tens of millions of pregnancies every year. The same family of diseases that killed his father and brothers became preventable because of him.

Then Dr. Sidney Farber called from Boston with an idea: maybe a drug that blocked folic acid in cancer cells could kill childhood leukemia. Subbarow’s team created the drug. They called it Aminopterin. In December 1947, Farber gave it to an eight-year-old boy dying from leukemia. Within weeks, the cancer cells began to disappear.

It was the first chemotherapy drug in history. The first time anyone had put cancer into remission using a pill. Subbarow’s team later refined it into Amethopterin, now known as methotrexate. It became a gold standard treatment for leukemia, lymphoma, breast cancer, and lung cancer. Then rheumatoid arthritis, psoriasis, and Crohn’s disease. The World Health Organization lists it as an essential medicine. Tens of millions of people use it every year.

In 1948, his lab produced Aureomycin. The first tetracycline antibiotic - a broad-spectrum one that killed typhus, cholera, pneumonia, and many bacteria that penicillin could not touch. It opened the door to the whole tetracycline family: doxycycline, minocycline, and drugs still used today against plague, malaria, anthrax, and drug-resistant infections.

He was 53 years old. He had created medicines that would save tens of millions of lives. August 8, 1948. Yellapragada Subbarow suffered a heart attack at his home in New York and died. No American newspaper gave him a front-page obituary. No university held a memorial. The Nobel Committee never honoured him. His own colleague George Hitchings later won a 1988 Nobel Prize for work built directly on Subbarow’s foundation. Subbarow was not even nominated.

In 1950, Argosy magazine published a feature about him titled “Miracle Man of the Miracle Drugs.” It began with a line that still hits hard. “You’ve probably never heard of Dr. Yellapragada Subbarow. Yet because he lived, you may be alive and are well today. Because he lived, you may live longer.”

Most Americans had not heard of him in 1950. Most still have not. Harvard has never officially honoured him. American medical schools mostly do not teach his name. The Nobel Committee that honoured Hitchings for work built on his foundation never corrected the record. Every methotrexate prescription written today remains silent about the man behind it.

India remembers. The government issued a postage stamp for his 100th birthday. His childhood home became a museum. Indian medical schools teach his name. But the country that denied him tenure, refused to let him bowl, and allowed him to die unknown - the same country that uses his drugs every day - still mostly does not know him.

Here is the truth. If someone you know has ever taken methotrexate for cancer or an autoimmune disease. If someone you love has taken folic acid during pregnancy. If you have ever been prescribed doxycycline for an infection. That was him. Yellapragada Subbarow. Born 1895. Died 1948. Saved tens of millions of lives, while a country he loved barely knows what it owes him.

Please remember his name and let your near and dear know about this little-known scientific legend born on this soil but never got the true recognition that he deserved. A story you need to know. A story all of us need to know. #Medicine #Unknownlegends @centerofright @KiranKS

[Hemanta Pathak @pathak_hemanta]

Intra government clashes has increased nowadays, we might be heading towards a breakdown

[Rajendra B. Aklekar @rajtoday]

Agra Cantonment station. RPF bullies drag and beat up Deputy Station Superintendent (DySS) on duty.

Incident as per preliminary info:

Visakhapatnam-Amritsar Hirakud Express arrived at Agra Cantt at 10.51 am and departed after its scheduled halt.

A woman passenger had deboarded the station to buy the famous sweet Petha and was trying to board the train after it had started moving. The Dy SS, noticing the situation, intervened and instructed the train manager over his walkie talkie to stop the train to ensure the passenger's safety.

The RPF personnel detained the husband and wife on allegations of alarm chain pulling (ACP), penalised them Rs 1,000.

This led to a dispute between RPF personnel and operating staff over the reason for the unscheduled halt.

The railways have set up an inquiry and will come up with a sanitised version of the incident.

[Hemanta Pathak @pathak_hemanta]

@Smart_Dummi Reminds me of the Sholay scene

[Hemanta Pathak @pathak_hemanta]

The curse of Indian civil services, the most inept and obnoxious people, worse than auto wallas.

[Lakshay Mehta @lakshaymehta08]

Two police officers stopped a man riding a scooty with his children in Rohtak and abused him for no reason.

When he asked them not to abuse in front of his kids, one officer allegedly slapped him 😳

Kids started crying after seeing their father being slapped. They were terrified.

GIRL: Papa, I wanted to be a police officer, but now I don’t want to. I hate police 😣

[AmbedkariteIN @AmbedkariteLM]

Retired Indian Air Force soldier Khazan Singh Jatav, who is currently working as a teacher in a government school in Uttar Pradesh, is sharing his heartbreaking story.

His son, Ayush Pratap Singh, who wanted to secure admission to IIT, was allegedly murdered by the school headmaster, Brahmin Jay Prakash Sharma.

The father claims that after he exposed the headmaster’s embezzlement of ₹6 lakh, his son was targeted and killed in revenge.

A soldier who served the country with full dedication is now forced to wander from door to door seeking justice for his son.

Justice must be delivered.

Can Dalits ever get justice in this country?

[Hemanta Pathak @pathak_hemanta]

@darab_farooqui https://t.co/96aN76U43H

Gill was responsible for killing Assamese youth protestors and had the audacity of disrespecting them much later in his life. Fool deserves no respect.

[Hemanta Pathak @pathak_hemanta]

@RahulSeeker Everyone should have the choice to follow what they feel. Forcing anyone doesn't make sense.

[Hemanta Pathak @pathak_hemanta]

@barandbench Why? The judicial system of India is making a mockery of justice system.

[Rajeev Bhattacharyya @rajkbhat]

There will be some activity on this just six months before next assembly polls in Assam. People will forget if the demand is accepted now. Public memory is short

No definite timeline for ST status to six communities in Assam: Government https://t.co/GFugKA4rBw via @IndiaTodayNE

[Hemanta Pathak @pathak_hemanta]

@sardesairajdeep Pretty unexpected. Took so long for ED?

[Angana Chakrabarti @AnganaCk]

I report on a seminar that was co-hosted by Assam Rifles and an RSS affiliate on Myanmar & Northeast India

In a nondescript Guwahati building, Assam Rifles' Director General and other officers shared a stage with members of the RSS and its affiliates.

What was discussed?

(Inspector General Assam Rifles (North) Maj. Gen. Harinder Singh Mavi addresses the gathering at the seminar👇)

Full report: https://t.co/Kmf28w8EiT

[SHREE RAM @JAWAHARNEHR]

I am writing this as an NRI. None of these idiots were asked by Australians to migrate to Australia. They moved there because they know exactly what life in India looks like. They were welcomed, allowed to study, work, make money, bring wives from India, receive permanent residency, and later obtain citizenship. And see what these savages are returning to the people who built that country. These scum have no shame, gratitude, gratefulness, or loyalty. They absolutely lack civic sense and basic common sense. These douchebags might find it fun to provoke them now, but Modi will not stay in Melbourne forever. These idiots will have to face their society.

[Arjun* @mxtaverse]

Dainik Bhaskar reports a scam of ₹1,160 Cr by Madhya Pradesh govt.

Officials allegedly sold fortified govt rice bought at ₹4,000/quintal to ethanol plants for ₹2,320.

Ethanol plants allegedly resold it to rice mills for ₹2,800, and bought broken rice for ₹2,100 for ethanol production.

The mills then allegedly supplied the same fortified rice back to the govt as freshly milled stock while selling the original paddy in the open market.

They allegedly did this with 50 lakh quintals of govt rice!

Double engine 🫡🙏🇮🇳

[Tehseen Poonawalla Official 🇮🇳 @tehseenp]

I just received a call from @DelhiPolice and they have said not to go tomorrow to the residence of Hon'ble Transport & Highway minster shri @nitin_gadkari ji! But Nitin sir, you gave us a challenge to to get people affected whose vehicles are affected by E20Fuel! Sir you please give us an appointment!!

Secondly sir: yesterday you said your son's Ethanol business is just 0.07%, this sir is roughly about ₹50-₹100 crores a year! How many INDIANS earn that kind of money? Sir with humility, this is BETA BADHAO YOJANA & a conflict of interest. Sir we await your revert!

Tehseen Poonawalla
Team Bharat

[Swati Chaturvedi @bainjal]

Kosher Jat Sikh behaviour of K P S Gill @tavleen_singh @HartoshSinghBal to quote your hero Modi Bajal here exposing Gill despite, being a woman

[Hemanta Pathak @pathak_hemanta]

@BRICSinfo Learn from Modi, use a teleprompter.

[Hemanta Pathak @pathak_hemanta]

@rajkbhat Unfortunately.

[RAHUL @RahulSeeker]

As we, Indians are such naive and never-adult populations that real stories like Satluj or Santosh get global praise but are banned in India

So let's dissect what we Indians deserve to watch -

🥇 No 1 condom ad by YASH Anna . Absolute blowjob energy. Anna Rocks! 🗿 🔥🧵1/4