PATHDET

PATHDET is a web application for “PATHogen DETection” from extracellular DNA/RNA via high-throughput sequencing data for infectious diseases. Dev by @cikazda.

[PATHDET @pathdet]

You can access the PATHDET REPORT (demo).
https://t.co/anoW7HN6D3
Demo data is from S. maltophilia bacteremia.
#pathdet #demo #infections

[Kazuhiro Horiba @cikazda]

Our study analyzing both pathogen detection and host gene expression in HLH patients has been published. Cell-free RNA profiling suggested mitochondrial RNAs as potential biomarkers of virus-associated HLH.
#mNGS #cfRNA #PATHDET
https://t.co/tfVdYDNe6D

[国立健康危機管理研究機構（JIHS ジース） @JIHS2025]

国立感染症研究所の病原体ゲノム解析研究センターでは、感染症を引き起こす細菌・真菌・ウイルス等のゲノム配列解析と情報提供を通じて、我が国の感染症対策の基盤となるゲノム研究を推進しています。#国立健康危機管理研究機構  #JIHS #国立感染症研究所 #NIID

[Kazuhiro Horiba @cikazda]

mNGS found Prevotella spp. in culture-negative pus samples in muscle abscesses.#metagenome #NGS #pathdet
https://t.co/VxWoffEbFq

[Kazuhiro Horiba @cikazda]

mNGS, using PATHDET pipeline, revealed Fusobacterium arthritis. #ngs #metagenome @pathdet
The contribution of metagenomic next-generation sequencing to a diagnosis of gas-producing Fusobacterium-induced septic hip arthritis: A case report
https://t.co/VxWoffEbFq

[Kazuhiro Horiba @cikazda]

PATHDET detected GAS in a pleural fluid using metagenomic NGS.
Severe Parapneumonic Effusion in a Child With Respiratory Syncytial Virus and Streptococcus pyogenes Coinfection https://t.co/RN9lZLVj3x

[PATHDET @pathdet]

PATHDET's Pathogen Prediction Method receives Japanese Patent, no.7373843.

[PATHDET @pathdet]

PATHDET web server is still under maintenance, but the analysis is available on our local env.; infectious diseases researchers who need metagenomic NGS analysis are welcome to contact us.

[PATHDET @pathdet]

PATHDET conducted metagenomic analysis in this study.

[Kazuhiro Horiba @cikazda]

Published online! Nanopore sequencing could comprehensively detect RNA viral pathogens in BALF samples with equivalent sensitivity and genome coverage as Illumina sequencing. https://t.co/6ttJWGkUTv
#nanopore #infection #metagenome #respiratory

[PATHDET @pathdet]

PATHDET contributed to the detection of #Ureaplasma in this study. #metagenome #newborn #chorioamnionitis

[Kazuhiro Horiba @cikazda]

We found, #Ureaplasma in the newborn's gastric fluid was connected to their mother's chorioamnionitis in cases of #newborn respiratory distress, according to #NGS. #metagenomics
https://t.co/Hgh68eUH82

[Maïwenn Kersaudy-Kerhoas @ClinicalMkk]

Is that just me, or Today's poster session @MicroTas2022 was quiet? Anyway, if you want yo chat about any of our posters, please DM! 🙏
Also please admire our colour matching poster selection 🤩
#microtas2022 #microfluidics #LabOnAChip

[Open Forum Infectious Diseases @OFIDJournal]

Performance of Nanopore and Illumina metagenomic sequencing for pathogen detection and transcriptome analysis in infantile central nervous system infections

✅ Just Accepted
🔓 Open Access
🔗 https://t.co/MF3krEIcCW

[PATHDET @pathdet]

PATHDET pipeline was used for metagenomic analysis for Illumina and Nanopore sequence data. An online version is now undergoing an update.

[Kazuhiro Horiba @cikazda]

We showed that #nanopore sequencing can be used for both #metagenomic and host #transcriptomic analysis from a single clinical sample with #infectious diseases. @OFIDJournal https://t.co/w62oNX2VCS

[PATHDET @pathdet]

PATHDET is currently being maintained. Test data results are opened to all users. Please email us if you have any questions! #pathdet

[Maïwenn Kersaudy-Kerhoas @ClinicalMkk]

I'm excited to speak at the free #WSCSpotlight on April 27! I will discuss our @iSEP_SEQ 'microfluidics + sequencing' approach to diagnose sepsis.
Join me and 35+ speakers discussing diagnostic approaches for #sepsis. For more info and free registration https://t.co/fI7dx0HU6B

[PATHDET @pathdet]

For server maintenance, PATHDET will not be available on the web to March 25th. If you need immediate analysis, please contact us by e-mail.

[PATHDET @pathdet]

The metagenomic NGS for pediatric febrile neutropenia by PATHDET was published in the OFID Volume 8 Issue 11 November 2021. https://t.co/NHU55MztkQ

[PATHDET @pathdet]

Currently, it may be difficult to connect to PATHDET. If you want an early analysis, please contact us by email. pathdet.message"at"https://t.co/zpwvy6m1qO

[PATHDET @pathdet]

Currently, PATHDET is down due to a server problem. Please wait for a while until it resumes.

[PATHDET @pathdet]

PATHDET is not available during am 9:00 Sep 29th - pm 18:00 on Sep 30th (Japan Standard Time) due to server maintenance.

[PATHDET @pathdet]

The analysis of 112 febrile neutropenic children's blood by PATHDET was reported in the OFID. https://t.co/NHU55MhRWg
#pathogendetection #metagenome