Nice study on IgG dusting in primary versus secondary minimal change disease. "Punctate Podocyte IgG Staining Does Not Differentiate Primary from Secondary Minimal Change Disease" #renalpath#nephrology https://t.co/1AWd1bf86V
@JZRenalPath@AranzaPinedo Yes! Yes! Yes! I have quit the term apple green and call it yellow/orange or “the expected congophillic birefringence under cross polarized light.” Hoping the nephrologist who reads the report will make sense of it 😊🤷♀️
@Zhou1217001@JZRenalPath This is most likely a memory response. It will take at least 4-6 wks for new HLA ab to form to the levels detectable and injurious
@Zhou1217001@JZRenalPath Intriguing case 🧐 I believe with this typical viral inclusions& other features you can diagnose BKVN. Banff criteria states inclusion and/or IHC ( if remember it correctly:)). Because of low specificity, other viruses must be ruled out as much as possible.
How was your day?
Me: Fine. ☹️ But I didn’t get everything done that I wanted to.
Have you ever gotten everything done that you wanted to?
Me: Never
Don’t let your list of things to do define your worth. What you got done was enough. Tomorrow is another day.
@sarah_s_g@JZRenalPath@SethiRenalPath IF for C3 uses antibody against h-C3 component shared between activated and intact C3 molecules. Therefore, the deposition of C3 doesn’t mean C3 activation. Just C3 insudation in tissue due to injury. It may be activated or may not, depending on the context.
Been collaborating with Chandra Mohan's group for several years now given our mutual interest in lupus nephritis.
Here's free access until 9/20/23 to their work with imaging mass cytometry in proliferative lupus nephritis
https://t.co/sfcmALlstu
@JZRenalPath OMG 😳 fantastic case … reminder to look at the normal parenchyma of nephrectomy samples more carefully. how did the surgeon or the doctor who worked the patient up miss it? At least they should have caught the proteinuria!