Marthambles

Private Investor - Focus on biotech: “I always advise people never to give advice.” PGW

[Steve Inskeep @NPRinskeep]

!!

[Josh Wolfe @wolfejosh]

What the actual fuck

[Brian Allen @allenanalysis]

Trump is now reportedly responsible for roughly 27.7% of the entire U.S. national debt accumulated under all presidents combined.

That is an astonishing figure historically.

The national debt just crossed $39 trillion.

President Trump has added roughly $12–13 trillion to the debt across his two terms in office.

That’s approximately 30% of ALL U.S. national debt accumulated since 1789.

In 2016, Trump said he would pay down the national debt “over a period of eight years.”

Instead:

- First term: +$7.8 trillion
- Second term: roughly +$4–5 trillion already

And yes, COVID affected first-term spending.

It does not explain adding another trillion dollars every five months without a pandemic.

A political movement built on:
“fiscal conservatism”
“small government”
“balanced budgets”

has now overseen the largest debt expansion tied to any single presidency in American history.

[Gavin Newsom @GavinNewsom]

You won’t hear this on Fox News:

California just released a balanced budget that wipes out the deficit this year AND next — while protecting health care and safety nets.

Meanwhile, Trump ADDED $2.4 TRILLION to the federal deficit with his “Big Beautiful Betrayal.”

Republicans ruin budgets.
Democrats balance them.

Adulting matters.

[Michael McFaul @McFaul]

Congratulations @GavinNewsom and thank you.

[David French @DavidAFrench]

"Trump is circumventing Congress’s power of the purse. He’s circumventing the judiciary’s role in adjudicating disputes. By potentially granting settlements to people who possess no valid legal claim, he’s circumventing civil and criminal law. This is one of the most purely monarchical moments of a monarchical presidency." https://t.co/od2xnlANux

[Steven Rattner @SteveRattner]

Under Biden’s last year, the U.S. economy added an average of 122,000 jobs every month.

Under Trump, that average has collapsed to just 26,000 a month.

In Trump math, that’s a “500% decrease.” (Around 80% in real math.)

My @Morning_Joe Chart:

[Joe Weisenthal @TheStalwart]

*US 30-YEAR TREASURY YIELD RISES TO 5.177%, HIGHEST SINCE 2007

[Marthambles @pbindler]

@JamesSurowiecki If this gets to court, I don't see how Trump will be allowed to do this without Congressional authorization.

[Marthambles @pbindler]

@pick1998_2 Interest rates

[TFTC @TFTC21]

Ken Griffin went home on a Friday "fairly depressed" after watching AI agents at Citadel do work that used to take teams of PhDs in finance months to complete. Done in days.

His words: "These are not mid-tier white collar jobs. These are extraordinarily high skilled jobs being automated by agentic AI."

This is the head of one of the most successful hedge funds in history saying the people he pays seven figures to analyze markets and structure deals are being replaced by software that works in hours instead of months. Not theoretically. In his own office. Right now.

The Coatue deck we covered earlier this week called agents "the biggest unlock" in AI. Griffin just confirmed it from the buy side. The shift from copilots to agents is not a future event. It is already happening at the highest levels of finance.

[Daniel Goldman @danielsgoldman]

Real story:

Judge was about to throw out the case bc Trump controls both parties.

Before it’s dismissed, Trump tells both parties to reach a “settlement.”

Settlement shields Trump from any future audit and creates a secret slush fund that can dole out money to anyone with no transparency.

Mind-boggling corruption.

@SpeakerJohnson - you may not know it, but your job is to conduct oversight of the admin. You can’t run away from this one.

[Aaron Rupar @atrupar]

Sen. Ron Johnson claims preposterously that as many as 3.9 MILLION (!!!) Americans died as a result of the covid vaccine

Complete insanity

[Steve Hou @stevehou]

@Noahpinion I think you were very excited about this. Have you followed closely?

[Marthambles @pbindler]

@Michigan_Value $HROW is also thinly traded. Easy to drive the price down with. very few shares.

[Daniel Dale @ddale8]

Pete Hegseth falsely testified to both the House and the Senate last week that troops were deployed to voting places in 15 states under Joe Biden in 2024.

Not only were all National Guard activations for the 2024 election ordered by individual states rather than Biden, all 11 states that responded to my inquiries told me that *zero troops* were sent to voting places.

The Pentagon declined to comment. Fact check: https://t.co/bwMFV9hPEV

[Mean Gene @meangenebio]

What a result

Using AI to detect pancreatic cancer on routine abdominal CT scans 16 months before clinical diagnosis

Detection rates climbed 3x to 68% accuracy for cases more than two years before clinical diagnosis, unaided radiologists 23%

[Eric Topol @EricTopol]

No less, enabling the design de novo proteins, a brilliant review @nature
"Over the next five to ten years, we anticipate the design of sophisticated protein nanomachines and materials with functionality ranging far beyond that generated during natural evolution for a wide range of
applications in medicine, technology and sustainability,"

https://t.co/PKyvvHey2t

[Marthambles @pbindler]

@Biohazard3737 I only see ticks.

[James Surowiecki @JamesSurowiecki]

Is Todd Blanche also going to prosecute Jack Posobiec for supposedly threatening to assassinate the president?