Giuseppe Ciliberti

Medical Doctor 🩺 Interventional Cardiologist 🫀 PhD Candidate

[Scuderia Ferrari HP @ScuderiaFerrari]

P1!!!!!! @LewisHamilton 🔥🔥🔥🔥

[PCRonline 🫀 @PCRonline]

🔥 #EuroPCR 2026 Major Late-Breaking Trials: Long-term mortality following PCI with DES versus CABG for left main disease

An individual participant data meta-analysis of the SYNTAX, PRECOMBAT, NOBLE and EXCEL trials presented by Brian Bergmark showed no significant difference in all-cause mortality between DES PCI and CABG over 10-year follow-up in patients with left main coronary artery disease suitable for revascularisation.

Read the press release here: https://t.co/IWwgQBtbbU

@NievesGonzalo1 @CuissetDr @nicolasdumonte1

#LeftMain #PCI #CABG #CoronaryArteryDisease #InterventionalCardiology #ClinicalTrials

[PCRonline 🫀 @PCRonline]

#EuroPCR 2026 Major Late-Breaking Trials: Coronary revascularisation in patients undergoing TAVI

This meta-analysis, presented by @MdScarsini provides the most comprehensive individual participant data metaanalysis to date concerning the role of coronary revascularisation in patients with AS and CAD undergoing TAVI.

The findings indicate that routine PCI provides limited advantage compared with medical therapy.

A strategy of selective, physiology-guided PCI may be beneficial for patients with severe aortic stenosis and CAD undergoing hashtag#TAVI.

Read press release 🔗https://t.co/ws6opiZtKL

@CuissetDr @NievesGonzalo1 @nicolasdumonte1

#latebreakingtrials #interventionalcardiology #clinicalresearch #science

[EuroIntervention @EuroInterventio]

As TAVI expands to younger and more complex patients, preventing coronary obstruction is becoming increasingly important.
This review summarised evolving leaflet modification strategies — from BASILICA to ShortCut and UNICORN — aimed at improving procedural safety in high-risk TAVI and valve-in-valve interventions. #CardioTwitter #TAVI #BASILICA #StructuralHeart

https://t.co/fj0knFuXns

@sunnygoelmd @GilbertTangMD

[Giuseppe Biondi-Zoccai @gbiondizoccai]

In patients with non–LM bifurcation lesions a conservative strategy without systematic side branch intervention is associated with very rare procedural complications and is noninferior to a systematic side branch intervention regarding MI https://t.co/o6A8Evt7P9

[Carlo Tumscitz @skat_ct]

A Little trick to save the radial access for an arterial line after #PCI, thanks to @GianlucaCampo78 for the idea!

[EuroIntervention @EuroInterventio]

After TAVI, invasively measured transvalvular gradients—but not echocardiography-derived gradients— were associated with mortality up to 2 years. Echocardiography systematically overestimated gradients, particularly with balloon-expandable valves. Read more in our #EIJBestOf 👇
#CardioTwitter #TAVI

🔗https://t.co/Nb5dAvZLpB

@RikAdrMD @verhemel @Rjnuis @JoostDaemen @drnvanmieghem

[NEJM @NEJM]

Early surgery in asymptomatic patients with very severe aortic stenosis led to a lower risk of a composite of operative mortality or death from cardiovascular causes at 10 years than conservative care. Full RECOVERY trial results: https://t.co/tLqC25ccCJ

[The Lancet @TheLancet]

PCI before TAVI—necessary?

In patients with CAD, deferring PCI was noninferior to a PCI-first strategy at 1 year for the composite of death, MI, stroke, and major bleeding.

https://t.co/KwN2tauPyY #ACC26

[NEJM @NEJM]

Presented at #ACC26:

Among patients with unprotected left main coronary artery disease, intravascular ultrasonography–guided PCI did not result in a lower risk of ischemic events or death than angiography-guided PCI. Full OPTIMAL trial results: https://t.co/bJ51ghVFq2

Editorial: Seeing the Left Main Coronary Artery Clearly — Is IVUS Always Necessary? https://t.co/Om82iZjnAL

@ACCinTouch

[NEJM @NEJM]

Presented at #ACC26:

In the IVUS-CHIP trial involving patients undergoing complex high-risk PCI, the risk of target-vessel failure (a composite outcome) was not lower with intravascular ultrasound guidance than with angiography guidance. Full trial results: https://t.co/oqHofLJUi6

Editorial: IVUS — A Zigzag Path to Success https://t.co/hb7PwRPlR3

@ACCinTouch

[JACC Journals @JACCJournals]

In this RCT of complex bifurcation #PCI using DK crush technique, 1-year benefits of #IVUS-guided PCI were driven by achieving IVUS optimization targets, not IVUS use alone. https://t.co/Uv1QbERUUL #JACC #ACC26

[NEJM @NEJM]

Presented at #ACC26:

In the ALL-RISE trial, FFRangio (fractional flow reserve derived from angiography) was noninferior to pressure-wire–guided assessment in reducing risk among patients with intermediate coronary stenosis. Full trial results: https://t.co/rAdXWtlS7X

Editorial: Toward Broader Adoption of Coronary Physiological Assessment https://t.co/9MEfaDg9IO

@ACCinTouch

[JACC Journals @JACCJournals]

In patients with symptomatic single-vessel chronic total occlusion, percutaneous coronary intervention for coronary chronic total occlusion (CTO PCI) improves angina beyond placebo.

Get the details in #JACC: https://t.co/yX0FDuSOjl #ACC26 #PCI #CTO @dr_skhan1

[NEJM @NEJM]

Presented at #ACC26:

Among patients undergoing complex PCI, elective unloading with a microaxial flow pump did not reduce the risk of major adverse clinical outcomes as compared with standard care. Full CHIP-BCIS3 trial results: https://t.co/4Hgqf7PvZz

Editorial: Price of Protection — Microaxial Flow Pump in High-Risk PCI https://t.co/AjunvmGyOO

@ACCinTouch

[JACC Journals @JACCJournals]

Conservative management of #FFR ≤0.80 lesions was linked to higher cardiovascular risk compared with either #PCI of FFR ≤0.80 lesions or deferral of FFR >0.80 lesions, which had similar outcomes. https://t.co/psC81rY8mB

#JACCINT #TAVR

[NEJM @NEJM]

After coronary bypass for acute coronary syndrome, adding ticagrelor to aspirin did not reduce cardiovascular events but increased major bleeding at 1 year, as compared with aspirin alone. Full TACSI trial results and Research Summary: https://t.co/dnIiQbX1qF

[Giuseppe Ciliberti @peppefercil]

Intracoronary adjunctive therapies for ST-elevation myocardial infarction: a network meta-analysis of trials | European Heart Journal - Cardiovascular Pharmacotherapy | Oxford Academic https://t.co/9yfxmBxGcP

[NEJM @NEJM]

Presented at #SVIN25:

CREST-2: In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit. Full results: https://t.co/ojge1CjqiU

Editorial: Managing Asymptomatic Carotid Stenosis https://t.co/D9LH89Edyk

@svinsociety

[PCRonline 🫀 @PCRonline]

#TCT2025 🇺🇸 the OCVC-BIF study

🔗https://t.co/mi4KQ7Aalc

@ANazmiCalik reviews this study - presented by Takayuki Ishihara in San Francisco - which compared drug-coated versus conventional balloons 🎈 for treatment of side branches of bifurcation lesions.

#interventionalcardiology