My great honor to be admitted to @GordonConf “mechanism of membrane transport” session! Catching up with our beloved scientists and meeting new friends, listening to cutting-edge research at a picturesque site. It’s invaluable opportunity for communication and inspiration.
Great advancement in scientists' capability of studying the dynamics of neuronal circuits in behaviors. Congratulations to Don and the team and collaborators!
ATLAS, a rationally designed transsynaptic tracer is out today! Plasmids will soon be available on @Addgene addgene https://t.co/HjAKxof6eo
Many thanks to first authors Jackie Rivera and Haoyang Huang, and to collaborators, @blsabatini@Kanoski_Lab@vincentw_weng@beherring
Very cool. Bitter sensation and airway protective reflexes are actually mediated by cell types that despite different tissue distribution, share developmental trajectory (pou2f3) and sensory signaling pathway (T2R-TRPM5-Calhm).
✨New paper from my lab out now in @CellCellPress !
We identified pathways for airway protective reflexes—swallowing and coughing—in mice, driven by rare throat chemosensory cells that signal vagal nerves via channel synapses.
https://t.co/MeIl4Tbi5E
SGP congratulates Dr. Huanghe Yang on receiving the 2025 Paul F. Cranefield Award for his outstanding paper, “Niclosamide potentiates TMEM16A and induces vasoconstriction” https://t.co/Z21VWvCk0B
Alignment between heat activation and agonist activation of an ion channel!! (This study represents one step further in understanding the structural basis for TRP channels’ temperature regulation, from the previous one done with TRPM4, published a year ago also by Juan/Wei labs)!
It's my great honor to contribute a group of data to the work!
It is always exciting to see the long-sought-after findings that perfectly explain the phenomenon as we hypothesized, but then find something novel that points to the hidden unknown about the new channel.
Epitope tagging with genome editing in mice reveals that the proton channel OTOP1 is apically localized and not restricted to Type III “sour” taste receptor cells https://t.co/aHJwWIBsSK
The @CIRMnews has awarded over $28M to Stuart Lipton and @xinjin for studies on pollution’s role in autism & psychiatric risk genes. Using S-nitrosylation pathways & advanced genomic screens, the projects seek new insights into neuropsychiatric disorders. https://t.co/y0lejpxOSx
After all the transphobia, witch-hunting, and the despicable and unsportsmanlike disrespect shown by a handful of athletes - let THIS image be the one that stays with you:
After Imane Khelif won her gold medal bout her opponent, Yang Liu of China, embraced her with a smile.
I remembered as a kid reading about Jesse Owens, who won the gold medal in track-and-field at 1936 Olympics, crushing Hitler's propaganda of “Aryan supremacy”.
Now 2024 Paris witnessed Pan make history too!
Pan Zhanle: "Before the 4x100 relay on the first day, I greeted Chalmers [Australian swimmer] and he simply ignored me. Alexy of the US team, when we were training, splashed water on my coach; it just felt like they looked down on us."
This man let the hate flow through him.
Visited Acadia National Park after Gordon conference, as I did 8 years ago. The same view at different time and in different weathers (2024 vs 2016) is like the same protein structure of different conformations: You see the dynamics! :P sorry for my nerdy joke…
As an ion channel person, I've found myself learn a lot during this GRC, which is focused on transporters! The conference covers many disciplines in the membrane protein field, engages a variety of new technologies, bridges academia and industry. Thanks Prof Ryan for your hosting
@xinjin@liye_tsri Exploring mountains, trying new food, growing peaches and doing biological science are several ways of deeply understanding nature and must have some correlation. @liye_tsri is an expertise in all!