CRISPR screens are great at telling you what a gene is doing inside your cells. But what if you're interested in what's happening to its neighbors?
Today, I'm excited to share match-seq, a new method that deciphers cell-cell interactions using barcoded RNA transfer.
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Thanks to @MCBassik and @Satpathology for being the perfect mentors for a project that bridges CRISPR, tumor immunology, and single-cell genomics. Read more about match-seq here https://t.co/rNm12rR3l8
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Finally, using the Perturb-match dataset, we were able to predict the immune cell type that was responsible for sensitization from each perturbation.
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