Just shared at @KeystoneSymp a new @ArcInstitute discovery of the bridge RNA recombinase mechanism: a new class of natural RNA-guided systems that retains the key property of programmability from RNAi and CRISPR while enabling large-scale genome design beyond RNA and DNA cuts
I’m excited to share our work developing an antibody-directed strategy for delivering genome engineering tools to specific cell types, both outside and inside the body 🎯
Our paper using ProteinMPNN redesign for improved properties is up on JACS! Huge thanks to Reyes, @ikalvet, Sam, and many others for their work. Shout out to @JustasDauparas for developing such a groundbreaking (and versatile!) tool. @UWproteindesign
https://t.co/bLm0jFuOvF
Today we report in @NatureBiotech an engineered virus-like particle system for in vivo delivery of prime editor protein-RNA complexes. This PE-eVLP platform can support therapeutic prime editing in animal models of genetic disease.
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https://t.co/Z3bIKF0Cyg
At @nf_castle, four NFT experts (@KavitaGupta19, Oliver Halsman Rosenberg, @gmoneyNFT, + @MPtherealmvp) discuss:
*why NFTs, like EtherRocks, are valuable
*whether Solana Punks are like fake Chanel bags
*the challenges of linking off-chain assets to NFTs
https://t.co/0JqlPc2l1v
1/ The infrastructure bill is heading for a vote in the House.
Yes, the crypto provisions are just as bad as they were months ago. Yes, the impact of Section 6050I has been underexplored.
No, you don't need to call your reps. The political reality is: it's out of our hands now.
The infrastructure bill passed by the Senate and now pending in the House contains an overlooked “digital assets” provision that would be a disaster if it becomes law.
If infra bill passes: a short story
Any American business: we received your payment of 0.243 bitcoin, thanks for your business! One last thing: give us your SSN, address, DOB, occupation, copy of passport or DL, and this other info Treasury Sec’y Yellen wants from you...
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If you didn’t get the chance to attend Non-Fungible Castle in Prague, now you can enjoy a livestream recording of the entire conference! Thank you again to all of our moderators and speakers for such thought-provoking discussions! https://t.co/ErJDXNYFwq