Philipp Rescheneder

Bioinformatician at @nanopore | views are my own

[Keith Robison @OmicsOmicsBlog]

Human phased T2T (20 T2T chromosomes + 9 further scaffolds) assembly from standard ligation library + 10X PoreC on a single PromethION flowcell (the unreleased high output chemistry)

#Nanoporeconf

[Rosemary Sinclair Dokos @RosemaryDokos]

@nanopore ‘s Phil James presenting on multiomic investigations and chromatin accessibility at #ASHG24

[Ailsa MacCalman @ailsamaccalman1]

Incredible few days at the Nanopore Community Meeting. Thank you to @nanopore for inviting me to talk about our work looking into base-pair level chromatin accessibility @nickdlowens #nanoporeconf

[Marcus Stoiber @Stoibs11]

Applications group presenting breadth of data available from a single @nanopore flowcell. #nanoporeconf

[Chris Seymour @iiSeymour]

Dorado v0.8.0 #ncm24 release!

- v5.0 DNA transformer model performance improved for A100/H100 via kernel fusing, quantisation and leveraging i8 tensor cores.

- v5.1 RNA models with updated mod calling for m6A, pseU, and brand new calling of Inosine and m5C.

- Improved dorado correct performance, stability and flexibility.

- Introduces per-barcode configuration for poly(A) estimation with interrupted tails.

#nanoporeconf

https://t.co/13RCK9UI4d

[Marcus Stoiber @Stoibs11]

Incredible presentation from Noah Bryan (a high school student!!!) on the detection of contaminated drinking water. And a clever rhyming title too! #nanoporeconf

[Matthew Parker @bioinfomatt]

👀 @nanopore #EPI2ME is really everywhere! Now even on your @Apple iPad.

https://t.co/TSQdtDE1RZ

[Jeff Nivala @jeffnivala]

Published today in @Nature, we describe an approach for single-molecule protein reading on @nanopore arrays. By utilizing ClpX unfoldase to ratchet proteins through a CsgG nanopore, we achieved single-amino-acid sensitivity. https://t.co/ZTFNZkwpcj

[Mile Sikic @msikic]

Edlib sequence aligner, https://t.co/MjKazNVExU, has more than 500 starts now. Kudus to @MartinSosic, who did this for his master's thesis and has continued to improve it over the years!

[Rosemary Sinclair Dokos @RosemaryDokos]

A fantastic opportunity to keep breaking barriers on RNA biology

[Philipp Rescheneder @philres1]

@colindaven @AW_NGS @krannich479 @keygene @nanopore @msikic Great! Let us know how it went!

[Philipp Rescheneder @philres1]

@colindaven @AW_NGS @krannich479 @keygene @nanopore @msikic So far we also tried haploid honeybee and tetraploid coffee each using a single flowcell worth of data. Standard read length not ultra-long and no pore-c / parental data.

[Philipp Rescheneder @philres1]

@colindaven @AW_NGS @krannich479 @keygene @nanopore @msikic Hi Colin, if you are interested we have HG002 data (2 ULK flowcells) available here: https://t.co/SsRioOr2w2 including instructions on how we ran error correction and subsequence T2T assembly.

[Philipp Rescheneder @philres1]

@lh3lh3 @AlbertVilella @msikic @Dorylophile 's data after dark talk (which should be available on demand soon) has some more result for non-human and LSK assemblies.

[Philipp Rescheneder @philres1]

@lh3lh3 @AlbertVilella @msikic HG002 data for testing is available here: https://t.co/SsRioOquGu

[Chris Seymour @iiSeymour]

Open data set release for highly accurate @nanopore only telomere-to-telomere (T2T) assemblies #nanoporeconf

https://t.co/z8kdDsEB2T

[Daniel Fordham @fordham_dan]

Welcome to London ! At #nanoporeconf this year we will be live sequencing 10 Endangered and Critically Endangered Species to coincide with 10 years of London Calling. All supported through our https://t.co/YAahK2Wz2a programme. Please come speak to us about it @nanopore

[Daniel Fordham @fordham_dan]

Median qscore 26.36, read n50 91 kb. Please have a look and let us know how you get on

[Matthew Parker @bioinfomatt]

Check out the data from this experimental extremely high-accuracy, ultra-long sequencing kit here https://t.co/egZVnPmD5S

The numbers from this tech update are incredible.