Our research is online! We show that while young HSCs are fairly uniform, old HSCs harbor both “old” and “younger” subsets. Reducing the “old” subset alleviates aging phenotypes in old mice! https://t.co/77pEptoskZ
New study find that the elimination of defective immune stem cells (HSCs) alleviates aging in mice & transplantation of healthy HSCs into old animals extends their lifespan. Breakdown & implications below...🧵😯
Transplanting young Hematopoietic Stem Cells (or CD150 low) into old mice rejuvenates their blood's epigenetic age and boosts physical performance, 🩸 Improved muscle strength and even cognitive function.
Yuting Wang, Yi Zhang (2025): Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice. https://t.co/q6tW0lOkAK
Transplanting young Hematopoietic Stem Cells (or CD150 low) into old mice rejuvenates their blood's epigenetic age and boosts physical performance, 🩸 Improved muscle strength and even cognitive function.
Yuting Wang, Yi Zhang (2025): Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice. https://t.co/q6tW0lOkAK
(2/2)🌟 Reducing functionally defective old HSCs alleviates aging-related phenotypes in aged recipients.
These findings shed light on the potential of targeted HSC interventions to combat aging effects.
🔗 Explore our results here:
https://t.co/lgOOQVH9Uv
(1/2)Our latest research reveals groundbreaking insights into hematopoietic stem cell (HSC) rejuvenation:
🌟 Transplantation of young HSCs rejuvenates aged recipients.
🌟 Even in older mice, youthful HSC subpopulations persist.
https://t.co/lgOOQVH9Uv
@desipoika Hello, sir, pyglmnet is really a master piece, but I am just wondering how to get coefficients (beta values) when I use it. Thanks so much !