Marcelo Stark

🩺📉🧬Por una Ciencia sin ideologías ni desinformación. Anónimo, evito exposición mediática y duelo de prestigios: Afirmaciones c/ evidencia valen por sí mismas

[Marcelo Stark @polindromes]

Bueno y, estamos realmente en endemia gracias a vacunas + seroprevalencia?

Técnicamente sí, p/ falta:

🔹Que disminuya aún más nivel medio positividad (y posiblemente, severidad)

🔹Que olas sean más estacionales y previsibles, probablemente, sumandose a olas de otros coronas🙂

[Neil Stone @DrNeilStone]

A systematic review of 511 studies showed that COVID-19, RSV, and flu vaccines are safe and effective

[Neil Stone @DrNeilStone]

After 8 billion doses (yes 8 BILLION, not a typo) Covid vaccines are at this point one of the most tested medical interventions in history and one of the safest ever

[Marcelo Stark @polindromes]

@elvillegaschile Casi. No es exactamente lo que diría Villegas. Léeselo.

[Marcelo Stark @polindromes]

@Jou_Kaiser Eso es falso hombre, no tiene sustento en la realidad evidenciable.

Es sólo el bla-bla de un político antivacunas, similar a ti. Es todo.

Te timaron de nuevo.

Si sigues siendo crédulo y retuiteando falsedades de charlatanes que lucran mintiendo, no te van a tomar en serio.

[NBC News @NBCNews]

No child deaths have been definitively linked to Covid vaccines, according to a report from the FDA that was quietly made public. https://t.co/N99uOgFTQ9

[Leandro von Werra @lvwerra]

We are releasing Carbon: a crazy fast DNA model

Carbon is 275x faster than the next best model. So fast you can process the whole human genome on a single GPU in <2 days.

Here are the tricks we used:

When modelling DNA sequences a lot of the performance comes down to tokenizing the sequences in a smart way. BPE tokenizer struggle because there are no whitespaces and character (called base in DNA) level tokenizers waste a lot of compute on too many tokens.

Carbon is built with a unique tokenizer: we split sequences in chunks of 6 bases, but during both training and inference we can work with single base resolution. That's similar to having word tokens but resolving them at the character level. All possible thanks to the DNA tokens unique structure.

The architecture combined with the tokenizer makes the model 275x faster than the previous SoTA (Evo2) at this size.

We built an interactive demo so you can explore how the model can generate DNA sequences, investigate the structure of genes, predict the effect of mutations, generate and fold proteins and even reconstruct parts of the tree of life.

https://t.co/OWEUoxAFjG

[Marcelo Stark @polindromes]

@elvillegaschile @latercera Claro campeón! la satisfacción con la vida y felicidad, también se correlaciona con el consumo de café nacional y el número de bandas de rock del país, entre otras relaciones espureas chistosas

[Stanford Medicine @StanfordMed]

Stanford Medicine researchers and their colleagues invented a new vaccine that shows potential to protect against respiratory viruses, bacteria and allergens — the closest yet to a universal vaccine.
https://t.co/ypukWUmJKv

[Marcelo Stark @polindromes]

@Danizamira @uchile Claro, lo bueno del papel impreso es que es casi indestructible, casi no ocupa espacio y se pueden hacer miles de copias y distribuirlas por el mundo en un instante

[Marcelo Stark @polindromes]

@Rebecca21951651 @angie_rasmussen @MichaelWorobey @jepekar @ScienceMagazine It's just a matter of time. For the next pandemic, there will almost certainly be some, ahem, “prominent scientists” claiming it was lab leak, even if the evidence points to the contrary.

[Marcelo Stark @polindromes]

@BenjaminMorenob Es el mismo que en tiempos de la pandemia decía que el gobieno de Piñera falseaba cifras y estaba matando gente y que había que encerrar más a la gente

https://t.co/j3XTR7CIPA

[Neil Stone @DrNeilStone]

Vaccine Anti vaccine
research research

[Balázs Szigeti @psybalazs]

I know its repetitive and boring, but one more time to drive home the point: another #psilocybin trial on major #depression, another missing #placebo response.

This time the placebo response is merely ~2.4 points, which is less than ~1/3 of antidepressant trials. This lack of a placebo response drives the large between-arm effect (~7.3), while the patient improvement after psilocybin is a respectable, but not great, ~10 MADRS units - its about ~12 after antidepressants.

If you are in San Francisco for the @APA conference, come and see my talk this topic on Sunday from 15:45 in room 206!

[Tyler Black, MD @tylerblack32]

https://t.co/1SSN2k91K1

[Jesus Ramirez-Bermudez @JRBneuropsiq]

🙏

[Marcelo Stark @polindromes]

@juancarlossaid Pero Said hombre, 2 dedos de frente.

Ella es una economista cercana a la izquierda y a Boric, de quien fue asesora y a favor de quien escribió varios artículos alabándolo... qué querías que dijera ahora, que le gusta la reforma de Kast?

Siempre me haces reír hombre

[Roger Seheult, MD @RogerSeheult]

It’s Friday the 8th and so far there is no evidence for any hantavirus infections in anyone who was not on the ship but had contact with someone on the ship anywhere in the world.

We have weeks to go before the incubation period is up.

This is why contact tracing is so important

But there are no confirmed cases outside of the ship.

[Francesco Branda @fbranda94]

🧬 Andes Virus Explorer

An interactive SEIR simulator for hantavirus ANDV — based on Martínez et al., NEJM 2020.

Adjust R₀, population size, isolation timing, and see how outbreaks evolve.

📘 Educational tool, not predictive.

🔗 https://t.co/7OuHjrxx9N

#Hantavirus

[Marcelo Stark @polindromes]

@Nesca3 @Farmaenfurecida Todos los que sean de riesgo y quieran evitar síndrome cardiopulmonar (HPS) o fiebre hemorrágica/síndrome renal (HFRS), UCI, ECMO y muerte, que es casi la mitad de los infectados y varios miles cada año.

[Marcelo Stark @polindromes]

@Farmaenfurecida En 3 meses más será historia, y el ciudadano común ni se acordará del hantavirus.

No habrá pandemia ni es eso remotamente posible por las características del virus.