We present a robust HDX-MS workflow for extracting amino-acid–level KD values from ligand titrations.
Shows excellent agreement with orthogonal biophysics + works on dynamic/tractable targets.
Thanks to co-authors.
🔗 Link to the preprint:
https://t.co/iOzEuqTWHz
🧪 Don't miss out on the action at the 5th UK Workshop on Membrane Proteins! Join us at Aston University, Birmingham, on 22-24 April for stimulating lectures, workshops, and hands-on lab sessions. Secure your spot today: https://t.co/YmjsCiXkNn
Exciting news for the molecular dynamics community! 🧬 The Molecular Dynamics Data Bank aka MDDB is going to launch. 🚀 Here's what you need to know about this new European repository for molecular dynamics simulations data👇
#structuralbiology#moleculardynaimcs#drugdesign
PhD opening in my lab at the University of Dundee open to UK-based students. Details in link below - reach out if you have any questions!
https://t.co/F88iXSAJ1X
We are recruiting a Molecular Interactions Research Associate!
If you are interested in Drug Discovery and you are experienced in Molecular Biology/Biochemistry/Biophysics please get in touch
👇
https://t.co/RFysgPtNJV
We are recruiting a Molecular Interactions Research Associate!
If you are interested in Drug Discovery and you are experienced in Molecular Biology/Biochemistry/Biophysics please get in touch
👇
https://t.co/RFysgPtNJV
We are delighted to announce Dr Mattie Pawlowic @goldenpipette as the first recipient of our 2024 Early Career Research Awards! Mattie’s lab studies cryptosporidium biochemistry and drug discovery.
Despite heavy snow, we have managed to spend a day at Diamond last week to do some experiments. Thank You Andrew Quigley, Harish and Monika and @instructhub . Fantastic day!
The @DDU_Dundee has 5 cadidate drugs in clinical developement. Experienced #medicinalchemist ? This is your chance to join us to translate biology research into novel medicines for unmet medical need. Apply to be our next Head of Chemistry, https://t.co/yFF5sOQBxH #drugdiscovery
Excited to share our latest work describing MN714 – first-in-class covalent inhibitor of SOCS2, a substrate adaptor of Cul5 E3 ligase. A >5-years long journey in the making full of twists and surprises. Please Retweet! Thread below 1/13 https://t.co/eJrupngRy6
Thank you @KTN_Agrifood for inviting me to present our work @postis_v in the webinar today on "Innovating and Collaborating to Reduce & Reuse African Fresh Produce Waste Webinar". @araoyinbo_ayo and @BrigitaSim supported by @CBMNet_NIBB@ResearchTeamLBU