Proof Diagnostics

We’re harnessing CRISPR technology to unlock powerful molecular diagnostics for all, starting with COVID-19 testing. #moleculardiagnostics #covid19testing

[CRISPR Therapeutics @CRISPRTX]

Today, we announced our first quarter earnings results. Read more about our recent highlights and outlook: https://t.co/TlSyopci8x

[Proof Diagnostics @Proof_Dx]

Programmable delivery https://t.co/7YOoNkUTGR combined with programmable nucleases makes for a bright future for patients.

[Fyodor Urnov @UrnovFyodor]

Genomic therapies - ASO, AAV, CRISPR - for all?
👏👏👏 @CarolineSeydel for a nuanced, comprehensive piece on how the rapidly growing field of N=1 therapies aims to be the rising tide that lifts all boats. @timyu @oligogirl @stopbatten @eperlste
https://t.co/yRCrk7q6t4

[CRISPR Therapeutics @CRISPRTX]

We are pleased to share that we have entered into a new non-exclusive licensing agreement with Vertex for the use of @CRISPRTX's gene editing technology to accelerate development of Vertex’s hypoimmune cell therapies for type-1 diabetes (T1D). Read more: https://t.co/UDUTMRE0IU

[Proof Diagnostics @Proof_Dx]

UCLA-led study uses base editing to correct mutation that causes rare immune deficiency https://t.co/y8QoOD34Kb

[Helen O'Neill @DrHelenONeill]

Eric Olson showing 90% editing efficiency in human cardiac cells using adenine base editing.
Im going to say that again, 90% editing efficiency! Wish we could take a moment for just that. The astronomical increase in editing efficiencies is an achievement in itself. #HGESummit

[Intellia Therapeutics @intelliatx]

Listen to a replay of today’s fireside chat with Intellia CEO John Leonard, M.D., at the 43rd Annual @TDCowen Health Care Conference: https://t.co/Xq3WX850a5

[Helen O'Neill @DrHelenONeill]

Prime time! David Liu gives a breathtaking talk on the current practices of base editing. There have been over 200 patients to date that have been treated in clinical trials with therapies enabled by Crispr nucleases @davidrliu #HGESummit

[Proof Diagnostics @Proof_Dx]

Wish we could be there but following along closely this week.

[Colin Baker @airlockben]

@royalsociety @TheCrick #HumanGenomeEditingSummit begins. New therapies, #precisionmedicine, #CRISPR, #germline editing will all be on the agenda. It will be fascinating. @UrnovFyodor and @MelissaSCreary in this quick review of what's already being done: https://t.co/Vabm4c00nS

[Proof Diagnostics @Proof_Dx]

Congratulations to all involved. Groundbreaking for patients.

[Intellia Therapeutics @intelliatx]

#HAE News: @US_FDA cleared Intellia’s IND application to enroll patients in the U.S. in its Phase 2 study of NTLA-2002 for the treatment of #hereditaryangioedema: https://t.co/5q3ztpZjgp

[David R. Liu @davidrliu]

Today we report in @NatureMedicine a study led by Christine & Jonathan Seidman’s lab in which we used adenine base editing in vivo to correct a common mutation that causes hypertrophic cardiomyopathy (HCM), a disease that occurs in ~1 in 500 people (1/8)

[Proof Diagnostics @Proof_Dx]

Should be an excellent symposium.

[Fyodor Urnov @UrnovFyodor]

Grateful to @intelliatx and @VerveTx for advancing RNA-based #CRISPR therapeutics to clinical trials - with superb results to date.
Also grateful for the opportunity to speak about expanding the impact of this approach to areas of dire unmet medical need. #healthjustice @igisci

[Paras Sharma @paras_biotech]

Gene Thx Public/Pvt competitive landscape

[Mammoth Biosciences @mammothbiosci]

Today at 4:00PM PT, Mammoth CEO @martintrevor_ will be presenting at the 41st Annual J.P. Morgan Healthcare Conference. Trevor will discuss key milestones around our technology platform and clinical initiatives.

#JPM23 #Biotech #CRISPR #Healthcare

[Proof Diagnostics @Proof_Dx]

Beautiful work. We are just beginning our understanding of these enzymes. Exciting times ahead for both Dx and Tx.

[The New York Times @nytimes]

A life-size statue of Henrietta Lacks, the Black woman whose cancer cells were taken without her consent and were used for medical research, will be placed in a plaza previously named after the Confederate general Robert E. Lee in Roanoke, Virginia.
https://t.co/QaYbC60Std

[Proof Diagnostics @Proof_Dx]

Ever more important to ensure access to diverse human genome sequence data...Human Genetic Diversity Could Alter Off-Target Gene Editing Effects https://t.co/6muUMaCuUT via @clinicalomics

[Eric Topol @EricTopol]

The deaths from Covid in the first 2 years of the pandemic were nearly 3-fold reported—~15 million globally—by @WHO excess death calculations
https://t.co/YwZHD4ufC1
@Nature

[Rob Stein @robsteinnews]

CRISPR gene-editing improves cancer immunotherapy

https://t.co/AAarStrFbp

[Proof Diagnostics @Proof_Dx]

U.K. Invests Over $215M in Genomic Screening Research for Newborns and Cancer Patients https://t.co/x1BYU1IEpa via @clinicalomics