Seongyeol Park

MD-PhD | genomics, cancer evolution, somatic mutations, lineage tracing | postdoc at Stanford Medicine, Curtis lab.

[Inigo Martincorena @imartincorena]

Excited to share our latest work. Applying advanced single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune lymphocytes. [1/n] https://t.co/8kQZ0NWl7X

[Young Seok Ju @GenomeDoctor]

I am pleased to share our work on Cavendish bananas, a clonally propagated crop. Using somatic mutations from >100 bananas collected worldwide, we reconstructed their global dissemination history and genetic microevolution under large-scale cultivation.
https://t.co/O7eYrmG41Y

[Seongyeol Park @psy700]

@jakelee0711 Huge congratulations! Fantastic data and interpretations showing the detailed evolution of somatic copy numbers!

[Jake June-Koo Lee @jakelee0711]

1/n Have you ever wondered whether an amplified oncogene in a patient’s tumor (HER2/EGFR/CCND1/…) is carried on extrachromosomal DNA (ecDNA) vs embedded within a chromosome? Bulk WGS + genome graph can hint, but in practice it’s often hard to resolve. Here is our new preprint.

[Noah F. Greenwald @NoahGreenwald]

So excited to see our work profiling the tumor microenvironment in triple negative breast cancer out @NatureCancer! Please give it a read, super proud of this one :)
For a full description of what we found, see below for a detailed tweetorial. https://t.co/GPj6nK4b18

[Seongyeol Park @psy700]

I am honored to be part of this fellowship and look forward to engaging with experts.

[Cancer Research Institute @CancerResearch]

🎉 CRI is proud to announce our Fall 2024 class of CRI Irvington Postdoctoral Fellows and Immuno-Informatics Fellows! Meet the exceptional researchers who are investigating novel therapeutic strategies to harness the immune system against cancer: https://t.co/lLlajLLJZt

[Noah F. Greenwald @NoahGreenwald]

I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) https://t.co/5bajDEQ2rP

[Jolene Ranek @JoleneRanek]

Super excited to introduce QUICHE (Quantitative InterCellular Niche Enrichment) - a statistical method that can be used to discover local cellular niches differentially enriched in spatial regions, longitudinal samples, or clinical patient groups :) (1/10) https://t.co/wVcOrwL6A1

[Mangiante @LiseMangiante]

The Curtis Lab’s latest study on the genomic architecture of breast cancer from the pre-invasive to metastatic setting is now out in Nature! https://t.co/XHUeNAqoeA

[Shadi Basyuni @shadibasyuni]

🧬Excited to share highlights from our latest publication demonstrating preservation of clinical utility with whole genome sequencing (WGS) data generated from routine FFPE cancer biopsies! 🧵#CancerGenomics @SerenaNikZainal @EarlyCancerCam @MedGen_UOC

https://t.co/wOwsjEa665

[Inigo Martincorena @imartincorena]

Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]

[Seongyeol Park @psy700]

It was fantastic scientific event. I gained valuable insights into cancer research and connected with peers for discussions. Many thanks to @NCICancerBio and the organizing committee. #NCI_JI_2024

[Young Seok Ju @GenomeDoctor]

I am delighted that my company (@inocras) shows the utility of whole-genome sequencing in real-world oncology! A prospective study with Ajou Univ. Hospital.
https://t.co/iUUkMYeJzV

[Young Seok Ju @GenomeDoctor]

We are pleased that our analyses on somatic mitochondrial DNA mutations (mosaicism) in normal human cells are published! Great work @JisongAn. https://t.co/4txm4AoZ8x

[Andrea Sottoriva @AndreaSottoriva]

Does cancer #evolution & intra-tumour heterogeneity predict long-term relapse? We tested the evolutionary paradigm in prostate cancer clinical trials with long follow-up, combining genomics with digital histopathology: https://t.co/76aiiba2eP

[Seongyeol Park @psy700]

@jakelee0711 @BWFUND Congratulations on the amazing news!

[Andrea Sottoriva @AndreaSottoriva]

Open #PhD position in my lab @humantechnopole in Milan together with @polimi. #DataScience for cancer evolution. Use #MachineLearning methods to analyse and interpret cancer single cell data and understand how to design better treatments. Join us!

[Noah F. Greenwald @NoahGreenwald]

I'm super excited to share Nimbus, our algorithm for automatic classification of cellular marker expression in multiplexed image data! Nimbus is a pretrained deep learning model that works out of the box across panels with any combination of markers (1/x) https://t.co/F7qk9P5oXx

[Seongyeol Park @psy700]

@jakelee0711 @game_of_chroms @peter_j_park @elledge_stephen @SpecifiCancer @CancerGrand @TheMarkFdn Great work! Congratulation.

[Denis Wirtz @deniswirtz]

We have just updated our database of (496!) funding opportunities for early-career researchers/faculty.

For each entry, we provide link, $ amount, deadline, eligibility criteria.

Download this database for free here: https://t.co/RGXGrdpAjN