Ryan James

Boilermaker Grad.

[Ryan James @purdue3kgt]

When my wife asks why I’m having “just one more bourbon” 😂😂😂

[Ryan James @purdue3kgt]

@atioberoi Take me & my kid to the next home game and sit field level.

[Ryan James @purdue3kgt]

@nottellingyou73 What exchanges can it be bought on?

[Ryan James @purdue3kgt]

I just went 82-0, think you can go 82-0? https://t.co/MxkfcQ61ZX #NBA #82and0

[Hunter Williams @HunterEsoteric]

Retatrutide Phase 3 results just dropped. Read this.

70 pounds. That's the average weight loss at 12mg over 80 weeks. Not the best case. The average.

→ 45% of patients hit 30%+ body weight loss
→ That's bariatric surgery territory without the surgery
→ 65% dropped below the obesity BMI threshold completely
→ At 104 weeks they were still losing. No plateau.
→ Blood pressure down. Triglycerides down. Cholesterol down.
→ No cardiac signals. No liver signals.
→ Even 4mg produced 19% loss with fewer side effects than placebo

Everyone is going to post the numbers today. Here is what most of them won't explain.

The reason Retatrutide keeps working past 104 weeks when everything else stops is the glucagon receptor. Semaglutide and tirzepatide have no glucagon component. They suppress appetite and improve insulin sensitivity but they don't directly drive energy expenditure the way glucagon does.

Glucagon tells the liver to burn fat directly. It increases resting metabolic rate. It suppresses new fat creation from carbohydrates. That's the mechanism nobody is talking about today.

So while semaglutide patients are fighting a slowing metabolism and a body that has adapted to the drug, Retatrutide patients are still burning because the glucagon component keeps the metabolic furnace running.

This is also why Retatrutide users tend to lose more visceral fat and see better lipid improvements than tirzepatide users at equivalent weight loss. The liver is actively being targeted.

Semaglutide and tirzepatide both plateau around 60 to 72 weeks. Retatrutide was still dropping at 104.

I've been saying this for years and the data keeps proving it right.

Full data → https://t.co/5u4XE1JQAR

Clinical trial → https://t.co/Fl3LqsBGSv

[Ryan James @purdue3kgt]

@Cat5SMASHICANE Someone is going to enjoy an apple-finished venison filet!

[Ryan James @purdue3kgt]

@Ravenismeee Lawson

[Craig Mockobee @UncleCraig45]

Still unsigned..

Hey @NFL scouts you have nothing to lose by inviting @devin_mockobee to a Rookie Minicamp. This your chance to put him to the test against your best UDFA & Draft players.

Again please give him a call. I swear to God you have nothing to lose.

[Ryan James @purdue3kgt]

@THPGolf Scotty, GoLo

[Ryan James @purdue3kgt]

@MyGolfSpy Taylormade SIM2 driver - 9*

[Ryan James @purdue3kgt]

@Mike_kim714 @Titleist My day job* is to get my kids into golf so I can share the game I love with them!

[Michael S. Kim @Mike_kim714]

500k followers giveaway pt 1!

My golf bag plus some @Titleist goodies

Comment, like, repost to enter. Must be a follower

Clubs not included unfortunately*
Still need those for my day job

[Ryan James @purdue3kgt]

@stoolpresidente King Dough and Futuro

[NCAA March Madness @MarchMadnessMBB]

RT IF YOUR TEAM IS DANCING IN THE ELITE 8 🕺

#MarchMadness

[Ryan James @purdue3kgt]

@MWPutters My first doggo, Maddie.

[Ryan James @purdue3kgt]

@MWPutters Haha. Realized you’re probably in a different time zone. It’s 8:38 EST 😂

[Ryan James @purdue3kgt]

@WhaleEverything @NoLimitGains @grok Done

[Ryan James @purdue3kgt]

@Upgradercom @grok Me

[Ryan James @purdue3kgt]

@grok @rova_69 @TheInternMason @grok who is going to score tonight on MNF based off this number -0.0157?