Dr. Rami Burstein

Professor of Anesthesia and Neuroscience at Harvard Medical School
Vice Chair of Neuroscience at Beth Israel Deaconess Medical Center

[Paolo Martelletti @P_Martelletti]

It is now time to redirect the flow of #training in #headache research starting with onsite clinical #education in areas lacking a solid background. #OneHealthForHeadaches https://t.co/KDqCpbhQV0

[Sait Ashina @SaitAshina]

Our study in @JCephalalgia shows presence/absence of non-ictal #allodynia can be used to identify #galcanezumab responders with close to 80% accuracy and galcanezumab non-responders with close to 85% accuracy #migraine #headache #CGRP @ahsheadache
👉 https://t.co/EkjJmhGDCy

[European Headache Federation @EHF_Official]

Predicting response to anti-CGRP mABs.

This study found that older age, fewer prior treatment failures and no past history of immuno-rheumatologic disease may be associated with a better response to aforementioned therapy.

https://t.co/jRdWN7ByDJ

#migraine #headache

[Sait Ashina @SaitAshina]

Even a mild decrease in #migraine frequency by CGRP monoclonal antibody, #galcanezumab, is sufficient to partially reverse the excitability and responsivity of #neurons involved in generation of certain #triggers and potentially #premonitory symptoms 👉 https://t.co/wp6jDveVbq

[BIDMC Headache Center @bidmcheadache]

A CGRP monoclonal antibody, #galcanezumab, reduced incidence of #headache after occurrence of common premonitory symptoms and triggers in those patients in which it reduced migraine frequency by>30,>50 and>70%, but not by<30% @NeuroPsychBMC #migraine 👇
https://t.co/TTBJMAhRMy

[Cephalalgia @JCephalalgia]

"Non-ictal cephalic allodynia can be used to predict galcanezumab responders with nearly 80% accuracy and galcanezumab non-responders with nearly 85% accuracy". Find out more at: https://t.co/2NPSO8EiX4
#migraine #headache #ichd3matters

[Sait Ashina @SaitAshina]

Proposed explanation for why and how non-ictal #allodynia interferes with ability of CGRP monoclonal antibody, #galcanezumab, to prevent initiation of next headache. This may have clinical implications. #migraine #CGRP @JCephalalgia In our latest study👉https://t.co/YRhT5daXVb

[Dr. Rami Burstein @ramiburstein]

@SaitAshina Very informative.

[Sait Ashina @SaitAshina]

Headache diary is an important tool that can assist the #diagnosis of medication overuse #headache, help to monitor frequency of headache and track the medication use #migraine #diagnostic

[BIDMC Headache Center @bidmcheadache]

@LisaGfrerer and colleagues including @bidmcheadache @ramiburstein demonstrated that in responders, onabotA reduces proinflammatory gene expression and immune cell density mainly in calvarial periosteum and less so in neck muscles and fascia #migraine #Inflammation #painrelief

[Cephalalgia @JCephalalgia]

.@JCephalalgia @ihs_official @arne_may - Open Access for @JCephalalgia read the editorial - https://t.co/YAxxnMuJMe

[Sait Ashina @SaitAshina]

Our data shows that narrow band #green light reduces migrainous headache, #photophobia, #anxiety and improves sleep in majorly of patients with #migraine #AANAM 2022 @ramiburstein

[Brain @Brain1878]

Gfrerer et al. shed new light on how onabotulinumtoxinA helps prevent occipital headache and neck pain. https://t.co/0PTOoeVLcZ

[Dr. Rami Burstein @ramiburstein]

@DiseasePrimers Difficult to treat with so little understanding of pathophysiogy. Very well written. Kudos .

[Nature Reviews Disease Primers @DiseasePrimers]

Position number 6: we find our PrimeView on Tension-type #headache.

#BestOf2021
https://t.co/FOjBo38bQM

[Nature Reviews Disease Primers @DiseasePrimers]

Chronification of tension-type #headache involves sensitization of #spinal and supraspinal #neurons, and decreased antinociceptive activity from the brain https://t.co/rhNJXPBYYN

[Dr. Rami Burstein @ramiburstein]

@DiseasePrimers Great review

[Dr. Rami Burstein @ramiburstein]

@SaitAshina @DiseasePrimers Great review. Congrats.

[Sait Ashina @SaitAshina]

Our latest extensive review on tension-type headache #headache #tensiontypeheadache @DiseasePrimers 👇

[Dr. Rami Burstein @ramiburstein]

@ihs_official Great paper. Important topic. Waiting fir a breakthrough in understanding and treatment