Rachel O Dea

PostDoc in the Kulathu lab
Ubiquitin and friends enthusiast

[Rachel O Dea @RaRodea16]

SAVE THE DATE! The @EMBO workshop "Ubiquitin and Ubiquitin-like proteins in Health and Disease" will be on September 2026. Exciting line up of talks and an amazing location!
Organized by @YKulathu @polosimona1 Yifat Merbl and Claudio Joazeiro
#ubiquitin #UBL #Conference

[Rachel O Dea @RaRodea16]

@gallant_kai Congrats Everyone!

[Malte Gersch @MalteGersch]

Interested in Ubiquitin, Parkinson’s disease therapy, mitochondria or DUB inhibitors? This preprint may be for you:
We show how the deubiquitinase USP30 can specifically be inhibited & introduce a framework for DUB ligandability.

https://t.co/hD9nkeMrYj

Thread👇 – with movie!!

[Rachel O Dea @RaRodea16]

Delighted to say I have been awarded a MSCA/UKRI funded postdoctoral fellowship to investigate UFMylation at specific sites with
@YKulathu
. Looking forward to having a new favourite UBL.
@MSCActions
@UKRI_News @mrcppu

[Rachel O Dea @RaRodea16]

@jnpruneda @ohsummi Congrats Jonathan!

[Rachel O Dea @RaRodea16]

@DuccioConti @JPLab_ Great one to dust off the paper reading cobwebs with! Congrats again 😄

[Rachel O Dea @RaRodea16]

Great body of work defining the intricacies of how PLK1 regulates CENP-A deposition at centromeres. Congratulations on the pre-print @DuccioConti and everyone involved!

[MPI Dortmund @mpimoph]

New paper by the @maltegersch group in @angew_chem : N-Cyanopiperazines as Specific Covalent Inhibitors of theDeubiquitinating Enzyme UCHL1 #chemicalbiology #drugdiscovery

https://t.co/XYdhp5ppnV

[Rachel O Dea @RaRodea16]

@ActingTheGom @gallant_kai it has never been normal

[Rachel O Dea @RaRodea16]

@DublinTaxiDave There are a lot more cases of Irish Nationals murdering their partners than non-irish cases so our EU status for "making Ireland safe again" is pretty irrelevant. https://t.co/MQPqhFnYx3

[Danny Boy @Care2much18]

I find it sad the Irish far-right hijacked the suffering of Ashling's family to advance their own hatred, bigotry and racism.

It also deflects from an overarching problem.

This thread won't be easy to read but if anyone gets to the end of it, that problem will be self-evident.

[Rachel O Dea @RaRodea16]

@LOCthedreamer2 https://t.co/MQPqhFnYx3

[Danny Boy @Care2much18]

I find it sad the Irish far-right hijacked the suffering of Ashling's family to advance their own hatred, bigotry and racism.

It also deflects from an overarching problem.

This thread won't be easy to read but if anyone gets to the end of it, that problem will be self-evident.

[Rachel O Dea @RaRodea16]

Fantastic work led by Zhou in our group, see below his facile semisynthetic method for fluorescent tools which paved the way for an in-depth understanding of SUMO specificity and revealed some more secrets about my favourite DUBs (USP36 and USP16). @MalteGersch @mpimoph @J_A_C_S

[Top Science @isciverse]

Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases

@J_A_C_S @isciverse #Chemistry #chemed #scicomm #news #Technology #Tech #NewsBreak #research #science #AcademicTwitter

https://t.co/HlOL2bFufT

[Satpal Virdee @SatpalVirdee]

#ubiquitin
#E3ligases

[Rachel O Dea @RaRodea16]

Interested in the secret lives of DUBs (Or what made us so happy)? See below how we characterised surprising activity of 2 DUBs with a toolkit for the Ubl protein Fubi and found a new aspect of a ribosome protein maturation.https://t.co/5vWE8ixYLk @nature @mpimoph @MalteGersch

[MPI Dortmund @mpimoph]

Versatile enzymes: Mechanism of Fubi cross-reactive deubiquitinases for ribosomal protein maturation - published by the @MalteGersch Group in @Nature Chemical Biology #ubiquitin #chemicalbiology

https://t.co/OYbsyyGWJy

[Rachel O Dea @RaRodea16]

Travel has started. Great to be returning to the fantastic Edinburgh DUB focused conference. Looking forward to the stories! @BiochemSoc #biochemevent

[MPI Dortmund @mpimoph]

Great #Campuslauf @TU_Dortmund ! We had lots of fun! And congrats to @AliciaPeschel @intein lab who ranked 5th in the women's category! #running

[SFB Targeted Protein Degradation @SFB_TPDvienna]

Big thanks to the organizing committee and CONGRATULATIONS to all the awardees of the Ubiquitin & Friends Symposium 2023 👏👏👏 #ubfriends2023

[Rachel O Dea @RaRodea16]

Thanks so much to the organisers and attendees for the great conference! It was a fun couple of days with inspiring science and people 😊

[SFB Targeted Protein Degradation @SFB_TPDvienna]

2 days filled with excellent talks, great posters, exciting science, and lively discussions. It's been such a pleasure and honor to host this amazing crowd of people at our #ubfriends2023 Ubiquitin & Friends Symposium 2023!

[PWO Galway @pwo_ug]

HAPPENING TOMORROW! PhD Researchers and Supporters will be demonstrating outside the library at 11am.

Why should you come? A thread:

#PGRsDeserveBetter
#phdlife
#CostOfLivingCrisis
@PWO_Ireland
@DeptofFHed
@uniofgalway

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[Rachel O Dea @RaRodea16]

@PantiBliss Are the t-shirts still available? 😀