Fernandez-Saiz Lab 👨‍🔬👩‍🔬

#Ubiquitin-driven molecular mechanisms in disease.

[Yogesh Kulathu @YKulathu]

Registration now open: 2026 #EMBO #Ubiquitin Workshop set in stunning Monopoli, Puglia 🇮🇹
Cutting edge science, great speakers, short talk opportunities, travel awards
Limited spaces. Dont miss out - register early!
Registration & more info: https://t.co/O29ToXHgoR

[Kotaro Fujii @KotaroFujii1]

Protein synthesis is not equally accurate across organs.

Excited to share our new preprint:
https://t.co/SKoTVsPspZ

We developed a new mouse model to quantitatively monitor translation errors and uncovered the spatiotemporal dynamics of the “quality” of protein synthesis.

[Mark A. Nakasone @Mark_A_Nakasone]

@DrSamuelBHume The proteasome inhibitors are amazing $ONXX was acquired for their second generation. A lot of people disagreed with the whole concept, but fast tracked in the end

[Samuel Hume @DrSamuelBHume]

How outcomes in relapsed/refractory multiple myeloma changed, from 1986 to 2026

[Peter Ottsjö @peterottsjo]

Nature Biotechnology has published a perspective mapping agentic AI systems in biomedical research. 163 cited works spanning drug discovery agents, autonomous experiment planning, and clinical reasoning.

The authors' recommendation is not full autonomy but "adaptive autonomy" - systems that know when to ask a human.

When a top journal publishes a taxonomy of a field, it usually means the field has grown faster than researchers can track. (And the problem my free newsletter BAIO solves! 😉)

[Judith Agudo @JudithAgudo1]

Metastasis kills most cancer patients and grows from invisible seeds. How do these seeds escape from attack by immune cells? These seeds harness stress hormones!🤯
⁦thanks to ⁦@nyscf⁩ ⁦@parkerici⁩ for their support. Today at ⁦@Nature⁩ https://t.co/rMKnHEqQwb

[Público @publico_es]

Adiós a Claus Knapp, el pediatra que descubrió que la #talidomida provocaba deformaciones a los bebés

✍️ Por Henrique Mariño (@solucionsalina)

https://t.co/LPD0KRn50S

[Jose Davia Herranz @HerranzDavia]

Fallece Claus Knapp el radiólogo infantil que descubrió que la #talidomida provocaba deformaciones en los bebés y evitó miles de nuevos casos en todo el mundo.
#medicina #Ciencia #Salud

[Molecular Cell @MolecularCell]

Online Now: Global profiling of nascent chain interactors reveals TRIM25 as a co-translational E3 ubiquitin ligase https://t.co/lD1qQqqnQW

[Keystone Symposia @KeystoneSymp]

The joint Keystone Symposium on The Ubiquitin Family in Biology & Disease / Proximity Based Biology & Therapeutics is now available on demand!

https://t.co/yxcY9Ju6xy
https://t.co/Tf0yNzuhGT

#KSUbiquitin26 #KSProximity26

[Yunha Hwang @Micro_Yunha]

Protein–protein interactions (PPIs) are key to discovering and interpreting new biological functions.

We’re excited to introduce 𝑭𝒍𝒂𝒔𝒉𝑷𝑷𝑰: a new application of gLM2 that uses genomic language modeling to predict proteome-wide PPIs in microbial genomes in minutes.

[Vienna BioCenter @viennabiocenter]

SAVE THE DATE: Ubiquitin & Friends Symposium 2026 on April 29-30 or even better, sign up now: https://t.co/ptLuR3oTcQ
It takes place at Van Swieten Hall, 1090 Vienna & is organized by the SFB Targeted Protein Degradation (incl. numerous research groups at Vienna BioCenter)

[@BioAI_Neuro @BioAI_Pharma]

AlphaFold is running out of data — so drug firms are building their own version
https://t.co/zGxAsj5uFM
#AlphaFold #BioAI #Proteinstructure

[Cell Chemical Biology @CellChemBiol]

Decoding E1-E2 specificity: How UBA6 prioritizes BIRC6 for ubiquitin conjugation https://t.co/nq5C6fE49D

[nature @Nature]

“It’s a major advance, on the scale of an AlphaFold4. The problem, of course, is that we know nothing of the details.”

Isomorphic Lab’s proprietary drug-discovery model is a major advance
https://t.co/AhhVEDOhP2

[Fernandez-Saiz Lab 👨‍🔬👩‍🔬 @UbiquitinLab]

Apply! 👇

[Oliver Hahn @Oliver__Hahn]

🚨 Postdoc position in my lab @calico is live!
I'm looking for someone deeply curious about the aging brain🧠⌛️, who wants to build novel scientific projects from scratch and carry them to publication and, ideally, into their own lab🥼🧪. No neuroscience background needed.

[Cell Chemical Biology @CellChemBiol]

Online now! Lysosome-targeting chimeras enable targeted protein degradation https://t.co/SimuXdMGTS #chembiol

[Rahul Samant @SamantLab]

We're #hiring a #postdoc--get in touch! Someone with expertise in 3D models (organoids/ALIs) and advanced imaging, and a passion to drive a project on how cellular #senescence and #proteostasis dysregulation contribute to tissue #ageing. Apply by 25th Feb https://t.co/8iZ7pv4ryX

[Cell Chemical Biology @CellChemBiol]

Online now! Advances in degradomics technologies to assess proteolytic cleavage events https://t.co/qn1EM7kfxQ #chembiol

[Kexin Huang @KexinHuang5]

Today we’re launching Phylo, a research lab studying agentic biology, backed by a $13.5M seed round co-led by @a16z and @MenloVentures / Anthology Fund @AnthropicAI.

We’re also introducing a research preview of Biomni Lab, the first Integrated Biology Environment (IBE), where we’re imagining a new way biologists work.

Biomni Lab uses agents to orchestrate hundreds of biological databases, software tools, molecular AI models, expert workflows, and even external research services in one workspace, supporting research end-to-end from question to experiment to result.

Agents handle the mechanics, while you define the question, then review, steer, and decide. Scientists end up spending more time on science: asking questions, understanding mechanisms, and eliminating diseases.

Phylo (@phylo_bio) is a spin-out of @ProjectBiomni, where we will maintain the open-source community and push open-science research. I’m grateful to continue building with my co-founders @YuanhaoQ @jure @lecong and the dream founding team @serena2z @TianweiShe @huangzixin20151 @gm2123 @margaretwhua @malayhgandhi.

We’re also fortunate to be advised by leading scientists @zhangf, Carolyn Bertozzi, and @fabian_theis, and supported by an amazing group of investors including @JorgeCondeBio @zakdoric Matt Kraning @ZettaVentures @dreidco @conviction @saranormous @svangel @valkyrie_vc and others.

Biomni Lab is available for free today: https://t.co/zYcXEjvIbb
Learn more in our launch post: https://t.co/O09cnwYeNg

We are also hosting launch events - join us at
South San Francisco: https://t.co/4Xm9DFf4cY
Virtual: https://t.co/Wf7ksnWkRy

We’re also hiring! https://t.co/PABaLLwmRx