Ray Gould

[Kelly Mulfaul @KellyMulfaul]

Thank you to the Knights Templar Eye Foundation for visiting to award a Career-Starter research grant to study mechanisms leading to vision loss in Batten disease retinal organoids.

[BioSpherix, LLC @BioSpherix]

It's here! GCCP 2.0 provides guidance on reproducible practices for in vitro cell culture in the modern age.

Read more (open access): https://t.co/FLsB0hN6bq

#cellculture #invitro #research

[BioSpherix, LLC @BioSpherix]

#1: Klein et al.'s 'A prevalent neglect of environmental control in mammalian cell culture calls for best practices' https://t.co/dpAcKcBn90

Congratulations @SteckbauerA @Shannon_grace_ @Samhan182 @SilviaArossa @Mo_Li_KAUST, and please pass our thanks on to your fellow authors!

[BioSpherix, LLC @BioSpherix]

The list is out! We picked our Top 9 Cytocentric Publications of 2021 https://t.co/KYxER3hMh2

#cellculture #cytocentric

[BioSpherix, LLC @BioSpherix]

We're still working on our holiday decorations... it's an exact science.

[The Hospital Research Foundation Group @hosp_research]

Adelaide will be the leading centre of excellence in the southern hemisphere for the treatment of chronic #pancreatitis with a purpose-built facility officially opened today!
A #BiospherixChamber has been purchased thanks to a $1.4M grant from THRF Group!
https://t.co/6s0DidX9Ca

[BioSpherix, LLC @BioSpherix]

Turning your oxygen studies up to eleven? Before you start, check out our tips and tricks: https://t.co/ONOvkmteb9

#Hypoxia #Physioxia #Anoxia #Oxygen #Cytocentric #Cellculture #Biology

[Sergiu P. Pasca @Sergiu_P_Pasca]

Delighted to share the latest paper in Cell @CellPressNews today— a comprehensive overview of human brain organogenesis in vivo, ex vivo & in vitro, including work using #assembloids, #organoids & disease models. Effort led by the amazing @kevinwkelley!
https://t.co/eeoVqIjI4a

[BioSpherix, LLC @BioSpherix]

Cytocentric cell culture: Zhidkova et al. disect the crosstalk that leads to enhanced pro-regeneration activity of MSCs co-cultured with ECs at physioxia.

Read more (open access): https://t.co/scYNC23Piv

#MSC #CellTherapy #Hypoxia #Physioxia #CoCulture #Cytocentric

[BioSpherix, LLC @BioSpherix]

Review: University College Dublin's Malkov et al. review the direct impact of cytokines on HIF signaling, and the multi-level crosstalk that shapes hypoxic inflammation.

Read more (open access): https://t.co/AiTE5vyGay

#hypoxia #inflammation #HIF #cytokines #InVitro #oxygen

[BioSpherix, LLC @BioSpherix]

HIF doesn't have to be life or death for your research.

Control oxygen in every step of cell culture: https://t.co/EpxFEwrTXL

#cellculture #invitro #invotroreproducibility #cytocentric #physioxia #hypoxia

[BioSpherix, LLC @BioSpherix]

Why keep incubator CO2 at 5%? How does cell handling temperature affect acidity?

Answers to these questions, and more, can be found on the Cytocentric Blog: https://t.co/UbTHNyZdcj

#Cellculture #InVitroReproducibility #Bioengineering #Biochemistry

[Jane Philpott @janephilpott]

Thoroughly enjoyed another visit to see the inspiring researchers at @queensutime & @QueensuCPU and to celebrate a $1 million gift from the W.J. Henderson Foundation & the @QueensuDOM faculty physicians to support translational research.

[BioSpherix Medical @BioSpherixMD]

Cell loss begins the moment you take your cells out of the incubator.

Learn more about full-time optimization: https://t.co/WDeu0OWEfG

#Cellculture #invitro #research #celltherapy #cytocentric

[BioSpherix Medical @BioSpherixMD]

Breakthrough Science: 2019 Nobel Laureate Gregg Semenza's review of the connections between oxygen sensing, HIF inhibition, and erythrocytosis. #Cytocentric #HIF #Hypoxia #Nobel #Blood

Read more: https://t.co/qjcf30QXgO

[BioSpherix Medical @BioSpherixMD]

Customer Publications: Bodkin and colleagues demonstrate that antioxidants mitigate IH-induced injury to the gut. Read more (open access): https://t.co/grLrYMcL9z
#InVitroReproducibility #Cytocentric #IntermittentHypoxia #antioxidants

[BioSpherix Medical @BioSpherixMD]

Customer Publications: Monaco et al use oxygen tension to tailor MSC differentiation in vitro.

Control oxygen in your own studies: https://t.co/wu74etPYSu

Read more (open access): https://t.co/sNPjr6ZUOy

#MSC #Hypoxia #Cytocentric #InVitroReproducibility

[Ray Gould @raygould10]

Why are CO2 Incubators Wrong for Cell Studies? | CO2 Incubators lack O2 control and modification of cell function by excessive O2 levels in room-air (21%) versus actual tissue values (<5%) contributes ROS artifact that limits in vitro translatability | https://t.co/YQEa6FQeNa

[Ray Gould @raygould10]

Why are typical #CellCulture Incubators Deficient? | 1. Microbial risk in status-quo incubators necessitates routine use of cell-toxic antibiotics and antimycotics which alter cell function in vitro | Interested in a bibliography? | Cells need #Cytocentric Incubation #InVitro

[Ray Gould @raygould10]

https://t.co/juKSrBD47P