Wende Lab

Research lab at @UABHeersink studying epigenetics, metabolism and heart disease

[Wende Lab @TheWendeLab]

@MahimaReddy11 wins at the 13th Annual CCVC Symposium!
@TheWendeLab Graduate student @MahimaReddy11 won 1st place for her poster presentation at the 13th Annual UAB Comprehensive Cardiovascular Center Symposium held October 1-2, 2026.

[John Chatham @JohnCChatham]

The latest collaboration with @AdamWende @TheWendeLab identifying “O‐GlcNAc memory” as a component of metabolic memory in the heart including @SamuelFChang & @CardioMyocyteHa plus many others. @UABPathology @UABHeersink @AHAScience @NIH #NHLBI #GlcNAc
https://t.co/UjxEVayRfk

[UAB Comprehensive Diabetes Center @UABDiabetes]

Meet Mahima Reddy, a Ph.D. candidate in the @AdamWende Lab in @UABPathology. Her research focuses on O-GlcNAc-driven cardiac remodeling, which is similar to the cardiac pathology seen in diabetes-related heart failure.

Read more: https://t.co/LHIdFLMzdB

[Adam R. Wende, PhD, FAHA @AdamWende]

Happy to report we have published a new study on "O-GlcNAc Memory". We hope that the findings will provide insight into the mechanism behind increased susceptibility to heart failure in patients with diabetes.
https://t.co/LhSgU7u3GH

[Wende Lab @TheWendeLab]

@MahimaReddy11 was also invited by the GRS to serve as the Discussion Leader for the early‑career researcher session, “Utilizing Omics and Large Data to Understand Cardiac Physiological and Pathological Mechanisms.”

[Wende Lab @TheWendeLab]

@MahimaReddy11 represents @TheWendeLab at 2026 Cardiac Regulatory Mechanisms Gordon Research Conference & Seminar

[Wende Lab @TheWendeLab]

@MahimaReddy11, a rising GS-3 in the @TheWendeLab presented posters on the lab's latest O-GlcNAc work at the 2026 Cardiac Regulatory Mechanisms Gordon Research Conference (GRC) and Seminar (GRS) in New London, New Hampshire.

[UAB Comprehensive Diabetes Center @UABDiabetes]

This month we get to know Md Saimoon Rahman, a 3rd year graduate student in the laboratory of Adam R. Wende, Ph.D. in @UABPathology.

Read more about Rahman here: https://t.co/0pXW5qGxV6

@TheWendeLab @AdamWende @Saimoon_Rahman

[Adam R. Wende, PhD, FAHA @AdamWende]

Excited about our new publication in Epigenetics defining a model to test glycemic memory and the potential role of glucose as a signaling molecule to lead to sustained susceptibility to exacerbated remodeling in response to subsequent pressure overload. https://t.co/slBEpSJ1EE

[European Society of Cardiology Journals @ESC_Journals]

Cardiac ageing & #HFpEF⏳

Explore cellular, structural & functional changes with #cardiac ageing & #heartfailure with preserved ejection fraction in this #CardiovascularResearch Spotlight Review
https://t.co/2IM6W7LACv

@CVR_TomaszGuzik @glenpyle @DrMikeDrozd @Sarah_KBrown #CVD

[UAB Cardiovascular Disease @UABCardiology]

🚨 Save the Date! UAB Cardiology presents the 12th Annual CCVC Symposium:"Revolutionizing Cardiovascular Medicine: Innovations in Human Disease Modeling & Therapeutics"
📅 October 9–10, 2025
🔗 Register Here: https://t.co/D2syhEPM5s

[JAHA @JAHA_AHA]

From 1970 to 2022 in the U.S. mortality for myocardial infarction⬇️89%, ischemic heart disease⬇️81%, while other heart disease, including heart failure,⬆️81%. #AHAJournals https://t.co/dBJgBWGACS

[John Chatham @JohnCChatham]

Latest collaboration between Martin Young's @JohnCChatham and @AdamWende lab focused on role of cardiomyocyte O-GlcNAc on circadian clock regulation. Full text coming soon!
https://t.co/6uiDgtDuZM

[Wende Lab @TheWendeLab]

We’re excited to share that Samuel F. Chang successfully defended his PhD on June 2, 2025! His dissertation explored how cardiac O-GlcNAcylation links diabetes to heart disease. Congrats, Dr. Chang on this remarkable achievement! @UABPathology @TheWendeLab @UAB_GBS

[Samuel Chang @SamuelFChang]

PhD✅
MD …loading…
6 years after starting my physician scientist journey, reached the big milestone of finishing my PhD!! 🎉Couldn’t have done it without the endless support of @AdamWende @TheWendeLab @UABMSTP @UABExerciseMed @UABPathology 🔬🩺

[UAB Pathology @UABPathology]

🎉 @AdamWende, Ph.D., associate professor in the Department of Pathology’s Division of Molecular and Cellular Pathology, has been awarded the senior faculty 2025 @UABHeersink Dean’s Excellence Award in Mentorship. Congratulations, Dr. Wende! Read more: https://t.co/xkBILhA6Xg

[Wende Lab @TheWendeLab]

@UABDiabetes highlights @TheWendeLab trainees @MahimaReddy11 & @Saimoon_Rahman presentations at 16th Annual Boshell Research Day.
-UCDC researchers present at 16th Annual Boshell Research Day
https://t.co/XNJJL49vG0

[Wende Lab @TheWendeLab]

@AdamWende presented his research at the @UABMicrobiology Department Seminar on “Nutrient driven epigenetic mechanisms of heart failure.”