Yannick Frey

PostDoc @ Medical University Innsbruck | Interested in membrane trafficking, signal transduction | space flight enthusiast

[OlayioyeLab @OlayioyeL]

Our new review on the DLC family of RhoGAP proteins is published! https://t.co/8G2a0kDCAs

[Yannick Frey @realYannickFrey]

Exciting research: Local plasma membrane curvature induces formation of PM-ER conctact sites #ER_literature
https://t.co/7FMtxXW3TG

[Yannick Frey @realYannickFrey]

Interesting new study: Apical vs. basolateral sorting at the Golgi might depend on size of cytoplasmic domain https://t.co/6Tjr7xsvX9

[Hesso Farhan @Hesso_F_Sci]

Happy to share our new paper out today in @embojournal. We identify SNRPB as a new regulator of ER proteostasis. We show that SNRPB is induced by the UPR and regulates the splicing of ERES proteins (e.g. Sec16A), thus controlling ER export of collagen-I. https://t.co/Z7OLwL4K9E

[Yannick Frey @realYannickFrey]

Interesting tool to monitor Sar1 activity in living cells:

https://t.co/fypT9t0QlR

[Yannick Frey @realYannickFrey]

Cool preprint out today!

https://t.co/pS3xIEAhPV

[Yannick Frey @realYannickFrey]

@AnnesoFio @FankhauserCh @ImagerieGif mStayGold maturation time appears to be ~15 min (in E.coli lysates, see Fig. S8). Maybe @SPOREMOHAN/@Allister_Crow have more info?

[Yannick Frey @realYannickFrey]

The membrane curvature inducing REEP1 proteins generate a novel ER-derived vesicular compartment
https://t.co/VZ8ZFDB1LD

#ERliterature

[Yannick Frey @realYannickFrey]

Interesting new study: GOT1A, GOT1B show opposing roles in attenuating FLI-06 mediated ER-export inhibition - Yet the direct mechanism of FLI-06 remains a puzzle #ER_Literature

https://t.co/72CGYSBjEr

[Yannick Frey @realYannickFrey]

Specific clearance of ER membrane proteins via PI3P-dependent transport to lysosome. Cool stuff!

https://t.co/pI7K5lL2Vy

[Yannick Frey @realYannickFrey]

Very cool!
https://t.co/lwKkoUXEa2

[BfR | German Federal Institute for Risk Assessment @bfren]

The @Bf3R_centre seminar with Professor Georgia Mason (@uofg) will take place on 24 July, 2023. The Bf3R seminars address issues related to the use of #AnimalExperiments and alternative methods in basic research and toxicology, as well as the 3Rs.

Info: https://t.co/4d0eGOD46r

[Yannick Frey @realYannickFrey]

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
https://t.co/FzupQUjOUs

[Hesso Farhan @Hesso_F_Sci]

7 PhD/Postdoc positions available in Innsbruck. Positions are part of two consortia projects (funded by @FWF_at) focusing on:
- Organelle Proteostasis in Cellular Growth & Quiescence
- Beating Blood Cancer- BCL2 Network Adaptations in B Cell Transformation
https://t.co/C9n8k4ksVx

[Angelika Hausser @AngelikaHausse7]

Molecular mechanism how phosphorylation induces PKD activation uncovered! Great interdiscliplinary collaboration with Ronja Reinhardt and Thomas Leonard from the @MaxPerutzlabs published now in PNAS. Check it out! https://t.co/jGxzywqCND

[Yannick Frey @realYannickFrey]

@tim_stasevich @SaraZaccara @NingInScience Awesome, so no reason why it shouldn't work😀 I might give it a try then!

[OlayioyeLab @OlayioyeL]

Two PhD student positions - Modeling and treating human cancer in a dish: ex vivo and de novo tissue systems - Apply now! https://t.co/lRCUwEjuSl

[Yannick Frey @realYannickFrey]

Hey @dow_lab, do you have BlasGo but with a red fluorescent protein reporter readily available (basically ScarGo but with an additional empty sgRNA scaffold)? Would save us some cloning time and money 😀

[Yannick Frey @realYannickFrey]

@joachimgoedhart Thanks! We got all the latest Rho FRET sensors, we're currently thinking about engineering GAP/GEF sensors. But nothing tangible yet :)