Renue by Science

💪🏻 Live better, longer
🔬High-absorption NAD+ & anti-aging formulas for real cellular health

[Renue by Science @renuebyscience]

A new Alzheimer's mouse study found that aerobic exercise plus resveratrol and fisetin produced the strongest increase in brain-supporting genes. BDNF rose nearly 5-fold, exceeding the effects of exercise or supplementation alone. Human studies are still needed.

https://t.co/iGKwb397Zv

[Renue by Science @renuebyscience]

A new clinical study found that 2 mg prolonged-release melatonin improved insomnia and depressive symptoms in adults with epilepsy without worsening seizure control. The findings suggest melatonin may offer a safe way to support both sleep and mood in this population.

https://t.co/VQjvP4x7JN

[Renue by Science @renuebyscience]

@SBakerMD Not bad!
3 meters more for a world record for 60-64 year olds.

[Renue by Science @renuebyscience]

A clinical trial found that 500 mg/day of trans-resveratrol improved cognitive performance, quality of life, and menopause-related symptoms in postmenopausal women. Participants also experienced lower diastolic blood pressure, higher magnesium levels, and reported greater energy with less fatigue after 3 months.

https://t.co/ICdKlfFMZf

[Renue by Science @renuebyscience]

A human clinical trial found that Urolithin A improved muscle strength, while 1,000 mg/day also increased aerobic fitness, walking distance, and exercise endurance. Benefits occurred without increases in muscle mass, suggesting improved muscle quality through effects on mitochondrial function, mitophagy, and inflammation.

https://t.co/lF5o3Y4GbM

[joely @joely]

@CharlesMBrenner In 2017, following a cardiac catheterization, I had sudden onset–debilitating–brain-fog. in 2021, increasingly desperate, I began taking 600 mg per day of Renue's Liposomal NR. In about a week it quelled the brain fog. When I told Dr. Ron Davis about this he nodded and smiled. 🙏

[Renue by Science @renuebyscience]

A small placebo-controlled trial found 250 mg/day NMN helped preserve retinal thickness in older men with type 2 diabetes, while placebo participants showed retinal thinning in the same region. Vision stayed stable in both groups.

https://t.co/6EEgniwUyg

[Renue by Science @renuebyscience]

New human data suggests the classic “NAD+ universally declines with age” model may be oversimplified. Blood NAD+ often stays stable, while tissue NAD+ (muscle, skin, brain) appears more tied to biological dysfunction, activity level, and health status.

https://t.co/KItaEOqPHW

[Renue by Science @renuebyscience]

A 2026 Friedreich’s ataxia trial found NR + exercise increased VO₂ ~12.7%, outperforming exercise alone (~9.5%). NR also increased whole-blood NAD+ levels, suggesting metabolic support may enhance exercise adaptation.

https://t.co/gxz0NdcDMT

[Renue by Science @renuebyscience]

A human trial found 10 mg melatonin nightly for 4 weeks improved eczema severity, itching, sleep quality, and quality of life in adults with atopic dermatitis, with no reported adverse effects.

https://t.co/KuuFnCWiH3

[Renue by Science @renuebyscience]

An RCT in men 40–70 found ashwagandha increased testosterone ~14.7% and DHEA-S ~18% over 8 weeks, with effects declining after stopping. Modest, but relevant for age-related hormone support.

https://t.co/CtkxjOFoWv

[Renue by Science @renuebyscience]

A meta-analysis of 10 RCTs (n=349) found NMN (250–1500 mg/day) reduced diastolic blood pressure by ~2.1 mmHg, with stronger systolic effects (~3.9 mmHg) in adults 60+. Modest but potentially meaningful for long-term cardiovascular risk.

https://t.co/NILXz2rehI

[Renue by Science @renuebyscience]

Big News: A human study found NMN and NR (1,200 mg/day) increased NAD+ in blood within ~2 weeks and in the brain by ~40% after 4 weeks, with levels declining gradually after stopping. Effects were consistent across healthy and Parkinson’s participants.

https://t.co/fhgdOwuzRH

[Renue by Science @renuebyscience]

A mouse study found NMN improved memory, reduced brain inflammation, restored gut barrier function, and activated Sirt1 pathways, reversing multiple markers of brain aging.

https://t.co/d7MtI5xc46

[Renue by Science @renuebyscience]

A 4-week human study found 700 mg GABA + 200 mg L-theanine improved sleep quality (−3 PSQI points), reduced nighttime heart rate, and lowered stress markers, with 84% of participants improving.

https://t.co/HEHYlqtAiI

[Renue by Science @renuebyscience]

Renue gets a shout-out from Andrew Huberman and Rhonda Patrick

"I take sublingual NMN. No relationship to any company that sells NMN. The one I take is from ... Renue by Science..."

https://t.co/Fjy2iRkmVT

[Andrew D. Huberman, Ph.D. @hubermanlab]

The new Huberman Lab episode is out: The Best Vitality & Health Protocols | Dr. Rhonda Patrick (@foundmyfitness)

0:00 Rhonda Patrick
2:40 Competition, Jumping Rope, Rope Flow
6:49 Rhonda's Exercise Routine, Cardiovascular & Resistance Training
12:30 Cognitive & Physical Benefits of Exercise, Serotonin & Impulse Control
14:40 Sponsors: Our Place & Lingo
17:03 Phones While Training?
18:45 Rhonda's Strength Training, Low-Reps, Modifications, Mental Resilience
27:00 Daily Protein Intake, Intermittent Fasting, Processed Carbohydrates
33:32 Lipopolysaccharide (LPS); Gut Permeability, Gluten; Cardiovascular Health
42:58 Sponsor: AG1
44:21 Tight Junctions, Gut, Neuroinflammation
47:26 L-glutamine, Immune System, Cancer Risk
54:55 N-acetylcysteine (NAC), Vitamin E; Antioxidant Balance, Reductive Stress
1:00:08 Starch, Tool: Bedtime Fast & Cardiovascular Health
1:03:36 Cortisol, Intermittent Fasting Benefits
1:08:09 Cortisol, Train Fasted?; Hormones, Visceral Fat
1:13:35 Visceral Fat, Perimenopause/Menopause, Insulin Resistance in Brain & Body
1:21:13 Sponsor: LMNT
1:22:33 Cortisol & Sleep
1:25:42 Intermittent Fasting, Metabolic Switch, Ketones, Muscle Loss?
1:36:47 Tools: Logic-Based Habits; Daily Metabolic Switch; Exercise, Autophagy
1:45:06 Exercise After Poor Sleep?; Training Breaks
1:52:47 Tool: "Exercise Snacks"; Sedentary Lifestyle & Cardiorespiratory Fitness
2:03:31 Sponsor: Function
2:05:16 Creatine, Dose, Resistance Training, Cognitive Function
2:17:43 Biology; Creatine; Supplement Safety
2:25:18 Omega-3s, Inflammation, Cancer Risk, Vitamin D; Trans Fat
2:36:52 Magnesium Threonate vs Bisglycinate, Sleep, Cognitive Benefit; Vitamin D
2:45:46 Supplement Types, Multivitamin, Coenzyme Q10, Urolithin A, Sulforaphane
2:55:10 Microplastics
2:57:26 Sponsor: Mateina
2:58:28 BPC-157, NMN, NR, Tool: Evaluating Supplements, Safety, Sources
3:06:28 L-Carnitine, Alpha-GPC, Nicotine, GABA & Ketogenic Diet
3:15:20 Nattokinase; Microplastics, Water Bottles; Seed Oils
3:22:21 Sauna, Creatine for Kids?, Bananas, Tool: Evaluating Studies
3:28:37 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Includes paid partnerships.

[Andrew D. Huberman, Ph.D. @hubermanlab]

The new Huberman Lab episode is out: The Best Vitality & Health Protocols | Dr. Rhonda Patrick (@foundmyfitness)

0:00 Rhonda Patrick
2:40 Competition, Jumping Rope, Rope Flow
6:49 Rhonda's Exercise Routine, Cardiovascular & Resistance Training
12:30 Cognitive & Physical Benefits of Exercise, Serotonin & Impulse Control
14:40 Sponsors: Our Place & Lingo
17:03 Phones While Training?
18:45 Rhonda's Strength Training, Low-Reps, Modifications, Mental Resilience
27:00 Daily Protein Intake, Intermittent Fasting, Processed Carbohydrates
33:32 Lipopolysaccharide (LPS); Gut Permeability, Gluten; Cardiovascular Health
42:58 Sponsor: AG1
44:21 Tight Junctions, Gut, Neuroinflammation
47:26 L-glutamine, Immune System, Cancer Risk
54:55 N-acetylcysteine (NAC), Vitamin E; Antioxidant Balance, Reductive Stress
1:00:08 Starch, Tool: Bedtime Fast & Cardiovascular Health
1:03:36 Cortisol, Intermittent Fasting Benefits
1:08:09 Cortisol, Train Fasted?; Hormones, Visceral Fat
1:13:35 Visceral Fat, Perimenopause/Menopause, Insulin Resistance in Brain & Body
1:21:13 Sponsor: LMNT
1:22:33 Cortisol & Sleep
1:25:42 Intermittent Fasting, Metabolic Switch, Ketones, Muscle Loss?
1:36:47 Tools: Logic-Based Habits; Daily Metabolic Switch; Exercise, Autophagy
1:45:06 Exercise After Poor Sleep?; Training Breaks
1:52:47 Tool: "Exercise Snacks"; Sedentary Lifestyle & Cardiorespiratory Fitness
2:03:31 Sponsor: Function
2:05:16 Creatine, Dose, Resistance Training, Cognitive Function
2:17:43 Biology; Creatine; Supplement Safety
2:25:18 Omega-3s, Inflammation, Cancer Risk, Vitamin D; Trans Fat
2:36:52 Magnesium Threonate vs Bisglycinate, Sleep, Cognitive Benefit; Vitamin D
2:45:46 Supplement Types, Multivitamin, Coenzyme Q10, Urolithin A, Sulforaphane
2:55:10 Microplastics
2:57:26 Sponsor: Mateina
2:58:28 BPC-157, NMN, NR, Tool: Evaluating Supplements, Safety, Sources
3:06:28 L-Carnitine, Alpha-GPC, Nicotine, GABA & Ketogenic Diet
3:15:20 Nattokinase; Microplastics, Water Bottles; Seed Oils
3:22:21 Sauna, Creatine for Kids?, Bananas, Tool: Evaluating Studies
3:28:37 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Includes paid partnerships.

[Renue by Science @renuebyscience]

A human RCT found 20 mg PQQ improved “body listening” (interoceptive awareness) after exhaustive exercise, while a single 300 mg NMN dose showed no acute effect.

https://t.co/bTCca7AxuT

[Renue by Science @renuebyscience]

A 24-week human study found a topical mix of NAM, NR, NAD⁺, and EGCG increased hair density while boosting cellular ATP (132.6%) and mitochondrial activity in dermal cells.

https://t.co/zqZVeTg9Ks