Robson F. de Souza

Biologist/bioinformatician working on sequence analysis at the University of São Paulo

[Robson F. de Souza @robfsouza]

Rejeite a Proposta de Redução do Orçamento da FAPESP! - Assine a petição! https://t.co/3hYyc22pRJ via @change_br

[Amar Deep @iamamardeeep]

In this bioRxiv preprint, we (@_KevinCorbett ) present the architecture and activation mechanism of the PARIS antiviral defense system. Thanks to our co-authors, @Lisa_Liang13, @EnustunEray, and @PoglianoJoe, for their support in shedding light on this Anti-anti-defense system.🧵

[Christoph Bleidorn @C_Blei]

Very happy to see our genome skimming tool Patchwork finally published with @GenomeBiolEvol! The software has been developed by @fethalen and Clara Koehne performed the benchmarking 1/2 https://t.co/e975ECd6iu

[Robson F. de Souza @robfsouza]

@DapengZhang5 I'm fine! Aravind told me you got tenure: much delayed congratulations! I was very happy to hear that! How about we chat on Friday, 18th? Is there a time in the afternoon you have available? Otherwise we can postpone it for the following week! Best wishes!

[Jean-Marie Volland @JeanVolland]

Very excited to share our preprint on "A centimeter-long bacterium with DNA compartmentalized in membrane-bound organelles"
#microbiology #chemosynthesis #CellBiology #bacteria
https://t.co/OPYIrkqz8S

[Jason Chin @infoecho]

I am sure bioinformatics wizards, especially experts in C programming, like @lh3lh3, will like this https://t.co/ptCEgbyLCs

[Thiago M. Venancio @tmvenancio]

Very proud of my former postdoc mentor, L. Aravind (@jivarahasya), elected fellow of the American Academy of Microbiology (2022)🔬🦠🧬.
One of the most brilliant scientist I've met. Well deserved! 🥂

[Robson F. de Souza @robfsouza]

@jivarahasya @ProteinVerse @ASMicrobiology Congratulations! Long overdue recognition!

[Atila Iamarino - atila.bsky.social @oatila]

https://t.co/5nRlv2klvV

[Kirill Medvedev @KirillEMedvedev]

We have finished a huge project studying all Rossmann-like proteins, which comprise 20% of all known 3D proteins structures. We figured out why they are so ubiquitous in nature. All data, papers and more details can be found here: https://t.co/gI8pQhLE5Y

[Aravind group @jivarahasya]

This prediction has now been tested and confirmed by just published work from Sandra Wolin's lab: https://t.co/2NfTQaq6EZ

[Aravind group @jivarahasya]

Everyone knows of nucleic acid double helices. But many peptide double helices are also made in nature: 2 of the famous ones are shown here. Quiz: What are these, which are some organisms producing them & how are they made?

[Aravind group @jivarahasya]

3 core components of these systems: 1) a rapidly-evolving TPR module likely recognizing invading elements fused to a histidine kinase. 2) A solo Receiver domain 3) A 2nd Rec domain fused to diverse effector domains including peptidases, nucleoside phosphorylases, &nucleases. 2/n

[Aravind group @jivarahasya]

While the generation of NAD+-derivatives as second messengers in these systems was proposed by us previously, here we identify a novel sensor for this signal: a specialized 7-TPR repeat domain with highly-conserved polar and aromatic residues.

[Marcio Vinicius Dias @MarcioDiasgroup]

our work about the first hexameric epoxide hydrolase from Streptomyces sp with @LuBruGonzaga

[Guilherme Lui @calisteninja]

"Por que vocês não falam dos RECUPERADOS?"

Ouviu ou falou isso? Segue o fio ilustrado pra entender se esse argumento faz sentido ou não

Se curtir, rola aquele RT pra ajudar? ❤️

[Diorge Souza @diorge_souza]

Happy to share our preprint on the structure of Vipp1 and why we believe Vipp1/PspA/Im30 proteins are ESCRT-III homologues, based on primary, secondary, tertiary and quaternary structural similarities. And my first scientific thread! https://t.co/krQX1xyOQq

[Aravind group @jivarahasya]

Here we report the discovery of two novel domains likely involved in adhesive interactions found in apicomplexans of the piroplasm lineage: the piroplasm β-strand (PiβS) domain and the Babesia α-helical cell surface (BAHCS) domain. https://t.co/rQCIWfQxRI