Roc Farriol-Duran

Computational Immunologist to be at @eapm_bsc @bsc_cns @carrerasIJC @uclcancer Stirring the pan at @eltallaret @embassat @cecitrics - he/him

[Roc Farriol-Duran @RocFarriol]

@O_VidalAparicio @jbadia16 @CarodRoviraJLl @dianacoromines @pauetvidal @VidalTranslates @mariusserra @juliaojedacaba @bibiloni @Joanlluislluis @EnricGoma PEC > PTA per tot arreu

[Roc Farriol-Duran @RocFarriol]

A first as lecturer for LIVE Vaccinology Masters #VaxInLive @UABBarcelona

Intro to AI in biomedicine and computational vaccine design.

Last tweet. NO longer XXX
See u in bluesky @rocfd

[Roc Farriol-Duran @RocFarriol]

@mdancho84 Thanks Matt. How are these or other options compatible with MS Power Point? Always found them interesting but never got to a straightfwd way to include them.

[Anna Appios @annappios]

So excited to share that our paper on the ever-elusive Langerhans cell is out now! Using a combo of in vivo models and RNAseq we have been able to identify some of the intrinsic and extrinsic signals that drive LC identity. Check it out! @BennettlabUCL

[Roc Farriol-Duran @RocFarriol]

@KaneFos @jamimmunology Big time Kane!

[Roc Farriol-Duran @RocFarriol]

📍Cancer Genomics, Multiomics & CompBio 🙌 @EACRnews

🔎#NIMBLE: early lung cancer detection clinical trial @uclcancer

🖥️#BREWPITOPES: we designed a surface-accessible epitope panel to capture early LUAD antibody signatures.

@kevlitchfield @eportacangen @EAPM_BSC @BSC_CNS

[Roc Farriol-Duran @RocFarriol]

6 months in London at @kevlitchfield lab @uclcancer @ucl have been highly stimulating. Came with 1 project, left with 5 😂 and learned loads in the process.

Now, happily back to @BSC_CNS @EAPM_BSC
Thanks @EACRnews for the fellowship!

Cheers to all 4th floorers!
See u soon 🙌

[Roc Farriol-Duran @RocFarriol]

Big shout to @mijr12 and @AlissaHummer for the organization 🔥

[Roc Farriol-Duran @RocFarriol]

Oxford📍
To present our structural work on TCRpHLA preds. Despite low # of crystal data, structures are informative and protein modelling tools are getting closer.

Such a day of struct bio & immuninformatic talks🙌🏽

@airr_community @BSC_CNS @Alfons_Valencia #miguel @EAPM_BSC

[Roc Farriol-Duran @RocFarriol]

Happy to chalk the whiteboard at London Quantitative Immunology day (my first ever) !!

We shared our implementation of #Brewpitopes (@BSC_CNS @EAPM_BSC @eportacangen ) on an early lung cancer detection study here at @UCL @kevlitchfield

Thanks @andimscience @YutaNotUtah 🙌🙌

[Roc Farriol-Duran @RocFarriol]

@drchristhorpe See you in a bit 🙌🏽🙌🏽

[Roc Farriol-Duran @RocFarriol]

@Raladid @FrontImmunol Likewise Ruben !

[Roc Farriol-Duran @RocFarriol]

😊 to introduce Brewpitopes at @FrontImmunol

A 🖥️ pipeline to refine (bioinformatic) B-cell epitope predictions into actionable candidates for therapeutic antibody & vaccine development.

#epitopes #antibody #vaccines #bioinformatics #docker #git

👇👇👇
https://t.co/BTLj2VeTQ7

[Roc Farriol-Duran @RocFarriol]

@carlotarp_ @FrontImmunol Thanks Carlota ! Good to hear from you :)
Hope is all well at the MD side of things.

[Ruben Lopez Aladid @Raladid]

@RocFarriol @FrontImmunol It has been a pleasure working with @RocFarriol; their knowledge and passion for science have made it possible for this manuscript to contribute to the understanding of epitope predictions. In the next chapter, we look forward to sharing the application to the wet lab!!!

[Eduard Porta @eportacangen]

Congrats Roc! Happy to have helped you in developing this very nice tool :)

[Roc Farriol-Duran @RocFarriol]

Go from an unmapped protein to a prioritized list of epitope regions.

Any target protein is at hand using Brewpitopes !

Docker & Git #openscience
https://t.co/IbHRq39xhM

Cheers to all the co-authors for support and advice!
@eportacangen @RespiratoryRSCH @EAPM_BSC @BSC_CNS

[Roc Farriol-Duran @RocFarriol]

How👷‍♀️👷?
- Epixtractor parses outputs > epitope seqs
- Epimerger harmonizes predictions
- Epitopology prioritizes extracellular regions
- Epiglycan filters out N- & O-glycosylations
- Epiaccess removes buried epitopes
- Epiconsensus integrates predictions > epitope regions

[Roc Farriol-Duran @RocFarriol]

@Kalary28 Glòria al Montseny! Ganes de tornar al Buxaus Michael!