Poncho El Boxer

Jusqu'ici tout va bien... Jusqu'ici tout va bien... Mais l'important c'est pas la chute. C'est l'atterrissage.

[MV Chandrakanth @ChandrakanthMv]

HELEN-006 and neoCARHP asked the same question:

Do we still need carboplatin in HER2+ early breast cancer?

Two phase III trials.
Two different designs.
One consistent signal.

✓ HELEN-006: Carboplatin-free THP improved pCR versus TCHP

✓ neoCARHP: Carboplatin-free THP preserved pCR versus TCbHP with lower toxicity

Together, these studies suggest that the contribution of carboplatin may be smaller than previously assumed in the era of dual HER2 blockade.

#BreastCancer #HER2Positive #HELEN006 #neoCARHP #Oncology #MedTwitter

[Paolo Tarantino @PTarantinoMD]

A challenge is that we have no ideal neoadj regimen:
-carbo in TCHP may not improve pCR
-no mature EFS with THP alone
-T-DXd-THP highly active but not powered on EFS

My recommended approach is depicted in this figure.

More nuance in our upcoming podcast: https://t.co/Hps4BarFFD

[Yakup Ergün @dr_yakupergun]

#ASCO26

Which treatments should continue with RT, and which should be held?

From the Great presentation by Dr. Corey W. Speers

[Yakup Ergün @dr_yakupergun]

#ASCO26

First-Line Therapy: Choosing the Endocrine Backbone for CDK4/6i

Alexandru E. Eniu, MD

[Yakup Ergün @dr_yakupergun]

Current approved treatment options for HR+, HER2− mBC

ESMO Guidelines: Real World Cases Webinar: Metastatic Breast Cancer 2026 presentation

https://t.co/H3S9DZXsK2

[Paolo Tarantino @PTarantinoMD]

The approval of T-DXd for the (neo)adjuvant treatment of HER2+ breast cancer will add an invaluable tool to our arsenal. Yet, in this era of right-sizing, not all patients require T-DXd treatment to be cured. Some thoughts in my recent JCO editorial. https://t.co/tKCgzzbdiq

[Orlando RPN @OrlandoRPN]

🚨 ALERTA 🚨 uno de los Antihipertensivos más comunes, la Hidroclorotiazida, acaba de ser catalogada de Riesgo Clase 1 para Cáncer de Piel y Labios… si tu lo usas o tus pacientes, la mejor opción es cambiarlo por otro medicamento

lo mismo con el Voriconazol y el Tacrolimus…

[Buitengebieden @buitengebieden]

There’s always one.. 😂

[Paul McCartney @PaulMcCartney]

Los Mexicanos son los mejores! What a night! 🇲🇽 #PaulMcCartneyGotBack

[Poncho El Boxer @rodbox44]

Les comparto nuestra publicación. Una contribución al conocimiento de la farmacogenética y el tratamiento para el cáncer de mama. https://t.co/e8ZFaK0FSL

[SIAC @SIAC_cardio]

Queremos invitarlos este Martes 18 a las 22 hs (ARG) a participar del "Programa de casos clínicos en CARDIO-ONCOLOGÍA" a cargo de los Drs. Nilda Espinola, Enrique Solórzano, Sandy Ruiz, Rodrigo Espinosa y Pedro López Velarde.
Evento online y gratuito: https://t.co/93CKvcPQVV

[Omar Peña Curiel @OmarOnco]

Vayan a @school_latin para ver esta plática de OVNIS 👽 🛸
.
.
@mivan_eduardo @anelcabrera @Dr_Zamudio @DrHectorDiaz @AChargy @DrDAGP_OM @rodbox44

[Trench @AcousticTrench]

It is with a very heavy heart to write this, Maple passed away last night. Maple has been my best friend over these past 12+ years and the bond we shared is indescribable. I feel so very lucky to have had her In my life. My heart aches. I love you Maple ❤️

[Poncho El Boxer @rodbox44]

@Aeromexico

[Ramírez Sandoval Juan C @jc25wing]

Ayer, mi querida amiga @Dra_CVillarreal publicó en Lancet el retraso en la atención de mujeres con cáncer de mama, debido al COVID y el cambio estructural en el modelo de atención. Un espejo de como múltiples padecimientos crónicos se dejaron de atender. https://t.co/NSAyA8EkSJ

[Juanjo Lara @JuanjoLara01]

Si dejas una cámara fija apuntando a la Vía Láctea, puedes apreciar perfectamente la rotación de la Tierra.

Y por mucho que lo sepas, es fascinante verlo.

[Mark Lewis, MD, FASCO @marklewismd]

If you fear mRNA I have very bad news for you about protein

[FlyByWire Simulations @FlyByWireSim]

Please ensure you keep engine/wing anti-ice on when flying through visual moisture with TAT below 10 degrees celsius.

[Cynthia Villarreal-Garza, MD DSc @Dra_CVillarreal]

Genomic signatures provide comparable prognostic information in young women with breast cancer and their older counterparts. These tests serve as important tools to refine the treatment decision-making process.

[Poncho El Boxer @rodbox44]

@OmarOnco @BrizioMoreno @Dr_Ivanoncologo @Dra_Cynthia_V @anelcabrera @DrAntonioBahena We still do not have direct comparissons between CDK4/6i+F500 and CDK4/6+AI in randomized controlled trials. The results from this meta-analysis are very informative however I would also wait for the SONIA trial to draw conclusions.