Important for the prevention and management of mineral and bone disorders from chronic electrolyte imbalance👇
https://t.co/EAHqteuyEL
Robert A. Fenton @rofe6065 & team show that a diet low in potassium causes bone loss in mice, effects that are attributable to altered calcium absorption by the kidney.
The figure shows deep learning instance segmentation model to identify kidney tubules and indicates low dietary K+ intake alters the abundance of the calcium-sensing receptor.
#BoneHealth
🫀 Today is #WorldHeartDay
🧩 The ISN presents: CKM Syndrome = Cardio–Kidney–Metabolic Syndrome
🔗 A new paradigm reframing diabetes, CKD & CVD as one interconnected web, not isolated diseases
📜 Here begins a 17-tweet deep dive
🧵Curated by @DrPSVali
#WorldHeartDay2025
Our mini-review highlights how basic science insights are relevant for developing approaches to treat water balance disorders and how long-term cell volume adaptation may contribute to cognitive impairment, bone loss and vascular calcification.
https://t.co/OiZ9hxgh64
If you are interested in a 2 year fully funded fellowship in Aarhus - check this out: https://t.co/nBcK3xlQWr
I would be happy to help you write a competitive proposal of mutual interest.
Check out this in @Kidney_Int. We show that NHE3 is important for Ca handling, but that the distal tubule compensates when NHE3 is inhibited by eg #sglt2 inhibitors. A team effort >9 years @RiegTimo@h_dimke @Adri_in_Aarhus @fenton_lab and others 👏🥂���
Genetic deletion of the #kidney sodium/proton exchanger-3 (#NHE3) does not alter calcium and phosphate balance due to compensatory responses
https://t.co/LsIQPujSSx
#OpenAccess@AarhusUni_int@USFHealth
Check out this issue for some excellent AQP articles. All originating in some form from the hugely succesful AQPS2022 meeting in Copenhagen sponsored by the Benzon Foundation
Our latest issue is out now! This issue is our "Aquaporins in health and disease" #SpecialIssue!
The featured cover image comes from Mack et al., which shows the transition from ependyma to choroid plexus in the human brain!
📖https://t.co/dJvrjLhQuX
22 years ago I published paper 2 of my research career in @AJPRenal, now it is paper 202, and happens to be AJPRenal. Support Society Journals!
Regulation of the water channel aquaporin-2 by cullin E3 ubiquitin ligases | American Journal of Physiology https://t.co/e1kYqABpBa