Cancer immunology lab at Dana Farber Cancer Institute applying synthetic biology tools to develop novel immunotherapies. #Immunotherapy#NK#CARs#BacterialEng
We engineered a new class of immunotherapy by surface displaying cytokines (il15/18 and 21) on a gut bacteria. Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses | Nature Biotechnology https://t.co/8SzWe081V5
Please check out our recent “In a Nutshell” article for brief updates on CAR-NK cell therapy for cancer. Lots of new exciting frontiers in the field! @lab_rezvani @MDAndersonNews @BrJHaem #CARNK#NK#Cell therapy. https://t.co/ikT5f7nrYU
@geneNclimate @romeerizwan Thanks! Yes we think this approach can be easily adapted to deliver other biologics and not just for the cancer immunotherapy
Bacteria engineered to target cancer. Bacteria expressing an anti-tumor signaling protein can be a potent cancer immunotherapy on Vimeo https://t.co/uTu8OqDDUB
Researchers from @DanaFarber, have engineered E. coli to function as a "tumor GPS," guiding cancer-fighting therapies directly to tumors. Published in @NatureBiotech, this innovation could transform solid tumor treatment. (1/3)