Rossjohn lab

Led by Prof @Jamie_Rossjohn FRS we are focused on understanding molecular bases underpinning protective and aberrant immunity

[Rossjohn lab @RossjohnLab]

In collaboration with labs
@PN0rmski @KatherineKedz @AndrewB34372462 @syctong and co-authors, paper published
@MonashUni:
An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania: Cell https://t.co/9zaAsJFCCP

[Klebanoff_Lab @KlebanoffLab]

🚨🧬An in vivo cell therapy engineering platform of transformative potential. Congratulations to @j_eyquem and team on a breathtaking (and groundbreaking) body of work. @parkerici @UCSF

https://t.co/d5D3ntBal0

[Dr Shane Huntington OAM @DrShaneRRR]

NHMRC Investigator Grants out today.
A devastating day for many. I have already received messages from some of the best researchers I know who have missed out.
The senior levels had a cutoff of 5.93 (females), 6.2 (males) - according to my sources.
The impact will be wide spread.

The damage being done at the moment to the sector is totally unacceptable. We need to do a lot more to support our research community.

[Australian Academy of Science @Science_Academy]

#StarsOfScience – Professor Jane Visvader's groundbreaking discoveries at @WEHI_research have fundamentally changed how we understand breast development and cancer.

[Rossjohn lab @RossjohnLab]

Congrats to PhD student, Liam Rashleigh, whose 1st authored paper on gd T cell receptor recognition was published today @Structure_CP
https://t.co/NON9BdFTpX
#GDTcellclub @MonashUni @RossjohnLab

[CD1-MR1 Immunology @CD1MR1]

Early bird registration pricing for CD1-MR1 2025 ends this Friday, 6th June! Get on it 👉👉 https://t.co/WeGrGMk0fF

[Prof. Jamie Rossjohn @Jamie_Rossjohn]

Congrats to Hien, 1st author of this study that arose from her hard work during her PhD.

[Prof. Jamie Rossjohn @Jamie_Rossjohn]

In collaboration with Moody lab, latest paper from @RossjohnLab describing the structure of a lipopeptide bound to a MHC-I like molecule found in chickens - hopefully this study will not ruffle too many feathers.

[Kedzierska Lab @kedzierskalab]

Your immune system gradually loses it top team players when we get older 👱➡️👵
Our study in @eBioMedicine investigates how long our good immune cells stay around – a 🧵⬇️ https://t.co/a6aak7bn2A
@CvandeSandt @KatherineKedz @TheDohertyInst #Influenza #AgingResearch

[Bruno Silva-Santos @BSilva_Santos]

Our latest paper demonstrating the potential of “our” DOT cells against colorectal cancer has just been published in @NatureCancer:
https://t.co/BK0Tg7VpL7
Many congrats to the whole team, especially @RafaelBlancoDom! :)

[Prof. Jamie Rossjohn @Jamie_Rossjohn]

Recent paper from lab describing a peptide-independent MHC-restricted T cell receptor https://t.co/k0zr3pZidG in collaboration with La Gruta lab @MonashUni @Monash_FMNHS @RossjohnLab @NatureComms

[Rossjohn lab @RossjohnLab]

In collaboration with @NicoleLaGruta1 and colleagues, latest paper from @Jamie_Rossjohn lab describing role of Lck-coreceptor assocation in T cell function. @MonashUni
https://t.co/Z5nQtQfIOL

[Science Immunology @SciImmunology]

Researchers in Science #Immunology have identified CD8+ T cells from human donors that can recognize naturally occurring influenza variants spanning more than 100 years, including the 1918 influenza A and 2024 #H5N1. @Jamie_Rossjohn @kedzierskalab

https://t.co/TMj791udTM

[Doherty Institute @TheDohertyInst]

🚨 Flu breakthrough! 🚨 Researchers at @TheDohertyInst & @MonashUni have discovered immune cells that recognise flu viruses even as they mutate—a further step toward a universal flu vaccine. https://t.co/pOJiqlZWAm @UniMelbMDHS @TheRMH @oanheei @Jamie_Rossjohn @kedzierskalab @KatherineKedz

[Kedzierska Lab @kedzierskalab]

Our latest study @SciImmunology identifies the molecular determinants of cross-reactive B35/NP418-restricted CD8+ T cells across IAVs from 1918 H1N1 to 2024 H5N1, and assesses their functionality.
@KatherineKedz @RossjohnLab

https://t.co/pSuhJ7jwyy

[Waggoner Lab @LabWaggoner]

TCR-peptide-HLA ternary structures define molecular mechanisms of TCR cross-reactivity toward natural influenza variants @SciImmunology
https://t.co/aAz6kmbDLl
@RossjohnLab @Jamie_Rossjohn @kedzierskalab @KatherineKedz

[Ricky Johnstone @JohnstoneRicky]

https://t.co/v3TqmbFwQa First paper from the @JohnstoneLab for the year and a brilliant collaboration with @TheDohertyInst colleagues Dan Utzschneider and Alex Kallies. Thanks to all @PeterMacRes @PeterMacCC for help and support and great job Dane Newman and Leonie Cluse!

[Prof. Jamie Rossjohn @Jamie_Rossjohn]

Ziggy enjoying park time #roughcollie

[Nicholas Fabiano, MD @NTFabiano]

Researchers paid $8.968 billion for their findings to be freely accessible.

🧵1/10

[Rossjohn lab @RossjohnLab]

https://t.co/gHOwb9TCyE

[Rossjohn lab @RossjohnLab]

Latest paper from lab, where Awad et al describe how cigarette smoke impacts that MAIT-MR1 axis and implications for lung diseases. In collaboration with Fairlie, Hansbro and Corbett labs https://t.co/hqlLiWHwsq
@MonashBDI @nhmrc @WaelAwadMoh @MonashUni @Jamie_Rossjohn @JExpMed