Roxana TEODOR

Views are my own.

[Roxana TEODOR @roxana_teodor]

Everyone who made this happen shows us that we are LIVING the impossible. How beautiful! Today’s heroes ride the horse of courage and carry the capes of competence. Humbling. Chapeau! As we stand in awe, let us gain a little courage ourselves and focus on increasing our own competence - whatever it may be that we need to deliver, even if it seems impossible, let us remember how we are living the impossible: not only are we in “the age of QWAIRo” (quantum, web2/3, AI, robotics), but also of space travel, to become a multi-planetary species. If none of these inspire awe, then play with a baby (or just pet a cat/dog/horse etc - whatever reminds us that it is all to serve life).

[Chris Hadfield @Cmdr_Hadfield]

We need heat shields to protect us, since we use the air to slow us down as we return to Earth.
From orbital speed, it gets to 1650°C / 3000°F. From the Moon: 2750°C / 5000°F.
For yesterday's Starship suborbital test flight, peak was 1450°C / 2600°F. Great to see the @SpaceX progress over the last 3 flights. Making them truly reusable is complex and necessary for permanent, cheap space access.
image compilation: @niccruzpatane

[Roxana TEODOR @roxana_teodor]

This is what wisdom is. Know it, recognise it, appreciate it…

[Clive G. Brown @The__Taybor]

You know, the only thing I ever feared at Oxford Nanopore, wasn’t failure, wasn’t risk, wasn’t running out of money, wasn’t personal criticism, wasn’t the technical challenges……. It was customer/ investor indifference.

[Roxana TEODOR @roxana_teodor]

Moving
Deeply moving (provided it is seen by a non-zombified human)…
Beautiful
As is everything that leaves one in awe at something greater than the self…

[Clive G. Brown @The__Taybor]

Can anyone out there lend Seth a P2S ?

[Roxana TEODOR @roxana_teodor]

@NorbertDragan @tonyszko Yes!
And now, imagine you could do sequencing at home (not only for the cyp1A2, but for your entire genome). Sounds like “tin foil hat” or “StarTrek” material? Look up “BBC sequencing in space”: the tech has been around for over 20 years and it’s been on the ISS since 2016.

[@BioAI_Neuro @BioAI_Pharma]

Many people from computing or software backgrounds assume biology works like computer code — something clean, modular, and easily programmable. But biology is fundamentally different: it is highly complex, nonlinear, dynamic, and multidimensional, shaped by evolution, stochasticity, context, and emergent interactions across scales. Living systems don’t behave like deterministic software; they adapt, compensate, and evolve in ways that often defy simple engineering assumptions.

[Roxana TEODOR @roxana_teodor]

One of the most impactful challenges ahead of us will be to appropriately manage the balance between centralisation (what stays “web2”)vs decentralisation (“web3”, or even altogether off-grid)… This is not neatly separated from the other major disrupting technologies - together, I call them “the age of QWAIRo” (quantum, web2/3, AI, Robotics) and our biggest challenge will be staying Life-Centric in the age of QWAIRo…
One key fact to watch for in emerging innovations will be “enabling choice” (not the regulation-induced box-ticking type, but the typical e built in by design). Just as a portable sequencer enables decentralisation and allows a user to deploy that technology offline, ZKP (and other cryptographic protocols) enables layers of privacy (with post-quantum cryptography becoming the tool enabling choice).
Exciting times ahead!!!

[Clive G. Brown @The__Taybor]

Following on from Kitchen table genomes/liquid biopsy. There are two forces at work, a centralization one and a decentralization one. Large companies are trying to trap everything in central data centers with proprietary data streams, giving them a moat and control, others are pushing to run AI and other things locally empowering individual users. Same is happening to bio/medical data including sequencing.

[Roxana TEODOR @roxana_teodor]

Whatever your views maybe about data privacy, the key word is still CHOICE.
Enabling genomic sequencing at home may be seen by some as unnecessary as computers and mobile phones were seen at one point.
The future of Care though is 3Ps: Precision, Personalisarion, Prevention (ideally, with participation and privacy by design). The good news is, the technology is already here…

[Seth Howes @SethSHowes]

I’ve wanted to do this for a decade.

But I never did - I refuse to give any company my DNA.

It is me.

So this week I sequenced my genome entirely at home. Literally on my kitchen table.

I never exposed my DNA sequence to the internet. Not at any point.

I used a MinION to do the sequencing (it’s smaller + weighs less than an iPhone).

I used open-source DNA models for the analysis (Evo2 and AlphaGenome) running locally on a DGX Spark and Mac Studio.

I traced mechanisms behind my family’s multigenerational autoimmune conditions that no clinician has been able to understand.

When I set out to do this I didn’t know if it would actually work. It does.

Your genome is the most private data you will ever have. You probably shouldn’t let it leave your house.

[Clive G. Brown @The__Taybor]

We looked at hospital air systems as an application, someone may have done it. During the pandemic i was advocating sequencing the air filter from aircraft, coz everything everyone breathes (or farts) ends up on it, also skin cells. They ended up sequencing the aircraft septic tank which, whilst OK, seemed a bit odd as not everyone goes to the loo on a flight but everyone is breathing.

[Roxana TEODOR @roxana_teodor]

Actually, the data IS there, we just need to know where to look. For example, in the UK, genomic testing (pharmacogenomics) has the potential to prevent a significant portion of adverse drug reactions (ADRs), which account for 1 in 16 hospital admissions and cost the NHS over £2 billion annually. A March 2025 study found that testing for just three genes could help prevent three-quarters (75%) of avoidable, severe side effects related to commonly prescribed medications. ALL the technology to make the 3Ps of Care (precision, personalisarion, prevention) a reality ARE already here - yet, soare the blockers. And the blockers collapse into 3 categories: knowledge, cost and behaviour modifications (with regulatory compliance being part of the latter). That’s actually GOOD news: it means we CAN overcome the obstacles!
Thank you for sharing this particular example of Milton Friedman’s works - we need his insights more than ever and they are more valid than ever…

[Roxana TEODOR @roxana_teodor]

Life is short and then we die, so when we notice something amusing or endearing, it’s like “petting a cat”: best to be enjoyed.
Enjoy:

[Roxana TEODOR @roxana_teodor]

What’s the word I’m looking for? Roflalm (rofl and fecepalm)? 😂🤣😂🤦‍♀️🤦‍♀️🤦‍♀️
It’s not too surprising that he may have been (most likely) quite unreasonable, but that every single negotiation failed is just utterly ridiculous… That no one said “just get him what he wants and shut up” seems like systemic silliness (quite pathetically so). Makes me agree with Rory Sutherland (on putting comedians in charge), but it boggles the mind that no one managed to find “the access key” for that inventor, with all the brilliant minds in the fields that could have benefitted from the innovation…
Roflalm…

[Roxana TEODOR @roxana_teodor]

PQ is not a “nice to have”, it becomes a must…

[nicolas, 30 ans @nic_carter]

read it the day it came out, it's a solid report but I disagree with their characterization of the urgency BTC devs are treating this problem with.

fact: there is no active PQ proposal being considered by BTC devs

fact: the most touted PQ proposal, BIP360, contains no post-quantum elements whatsoever. it just closes an issue with taproot

fact: by my count, only 1/12 of the most influential bitcoin devs have a proactive stance on quantum (source: https://t.co/n4Izb11dW1)

there is no post-quantum roadmap for Bitcoin. there is no post-quantum BIP. no major dev has endorsed any post-quantum BIP. these are all verifiable facts.

meanwhile, Ethereum declared it its top strategic priority (https://t.co/6qxFuZvJls)

[Roxana TEODOR @roxana_teodor]

@nic_carter @doodlestein Which is why perhaps Milton Friedman was right, that an actual UBI might be less objectionable than all the friction, parasitism, fraud, etc… What was it he used to say? Was it “Show me the incentives, I will show you the results”?

[Roxana TEODOR @roxana_teodor]

“The record of history is absolutely crystal clear”. We’d be very well served to remember history…

[Johnny Midnight ⚡️ @its_The_Dr]

One of the best explanations of Greed and How Capitalism is our only real escape from Poverty! Milton was Brilliant! Phil Donahue was more Philosophical, but when facts meet Philosophy Facts always win.

[Documenting Saylor @saylordocs]

Charlie Munger’s 1998 Harvard speech is the ultimate cheat code for life.

He compressed 74 years of billionaire wisdom into just 30 minutes.

Most people spend 4 years in college and learn less than what’s in this video.

Save this video, you will come back to this.

[Roxana TEODOR @roxana_teodor]

Think of it this way now for Care.

[Nic Cruz Patane @niccruzpatane]

Just a reminder why electric vehicles are better than gas cars:

[Roxana TEODOR @roxana_teodor]

@keystotheinner @CryptoJelleNL If they did include that, their shameless scam would be exposed to the entire population for exactly what it is and they wouldn’t be able to get away with it. As it is, they mask it as “tax the rich” and call it a victory for “compassion for the poor”. 🤦‍♀️ Ideologically possessed.

[Roxana TEODOR @roxana_teodor]

Experience BECOMING…

[Katyayani Shukla @aibytekat]

He literally explained why practicing art grows your soul—not your status.

[Roxana TEODOR @roxana_teodor]

“You ARE paying for it”

[Milton Friedman Quotes @MiltonFriedmanW]

Milton Friedman: “Keep your eye on one thing and one thing only: how much government is spending, because that’s the true tax.”

“If you’re not paying for it in the form of explicit taxes, you’re paying for it indirectly in the form of inflation or borrowing.”