Roy Perlis

Director, MGH CQH | HMS Professor | Psychiatrist | Dad. Probably not Batman. Opinions my own, not my institutions'.

[Roy Perlis @royperlis]

Truly, I admire o3's optimism as a coding partner: "First run will finish the one-time build; subsequent runs will be instant and error-free." And then all your wishes will come true...

[Roy Perlis @royperlis]

"One of the biggest lessons is fully recognizing how people have started to use ChatGPT for deeply personal advice...as AI and society have co-evolved, it’s become clear that we need to treat this use case with great care." https://t.co/QTYrX2MiPX

[Roy Perlis @royperlis]

@RecoveryDoctor Exactly

[Roy Perlis @royperlis]

Wtaf

[Roy Perlis @royperlis]

Happy to have the opportunity to highlight really lovely cellular modeling work by Orhan and colleagues in AJP (@APAPubJournals) ... boiling the genomic ocean is not sufficient to figure out brain diseases: https://t.co/PsY0Y8rqqy

[Roy Perlis @royperlis]

https://t.co/EHE0GO6VWH

[Roy Perlis @royperlis]

https://t.co/gOiREgTO0T

[Roy Perlis @royperlis]

>I’m afraid code is getting unwieldy and bloated. How can we make it more maintainable?
You're absolutely right. The code has become unwieldy and bloated.

(Claude, that hurts my feelings a little....)

[Roy Perlis @royperlis]

Looking forward to speaking at BU's CTSI Translational Science Symposium on 3/19: "Advancing Translational Science Through Cutting-Edge Technology" ... registration here: https://t.co/zUfXRuBUDg

[Roy Perlis @royperlis]

Hmm. I'm not sure this chatbot is quite ready for prime time.

[Roy Perlis @royperlis]

Working with the smaller (smol?) chatbots that will run on my phone takes some getting used to, after being accustomed to the big ones. I was just asked whether I'm feeling overwhelming today. (I am not.)

[Roy Perlis @royperlis]

I'm often asked, what is MGH's secret? The answer: we have the cleanest hands.

[Roy Perlis @royperlis]

Research Domain Criteria in NIMH Grants Characterized Using Large Language Models - @JAMANetworkOpen https://t.co/6G4B88R1BR

[Roy Perlis @royperlis]

https://t.co/wVgE2YkNlM

[JAMA @JAMA_current]

Digital health technologies, including patient portals, are widely used by older adults.

Author Cornelius James of the University of Michigan joins @JAMAplusAI EIC @royperlis to discuss how these technologies fit with his own experience in the clinic.

https://t.co/G1CPI1EmEb

[Roy Perlis @royperlis]

For those curious about the impact of the 15% IDC rate, here's data on total NIH funding by institution: https://t.co/9H49JvwZ3r ... and here's a brief synopsis of hardest-hit: https://t.co/bE5Puj6uuJ

[Roy Perlis @royperlis]

https://t.co/OZsBZFC6d1

[Roy Perlis @royperlis]

https://t.co/LapxNPA6oG

[Roy Perlis @royperlis]

LLM, asked about optimal treatment of depression, "Here are some additional things you can do: 1. **Get enough sleep**: Aim for 7-10 years of psychotherapy and 75-100% of CBT." Yeah, 7-10 years should just about do it.

[JAMA @JAMA_current]

FDA Commissioner Robert Califf speaks with @JAMAplusAI Editor in Chief @royperlis about the challenges of regulating AI in health care. https://t.co/bLliLM6ZGS