Hello, pharmacist here. JK is right on the key issue. Every human produces both estrogen and testosterone. Men and women who do not produce enough require exogenous replacement of what the body is failing to produce and this is what HRT is used for. Cross sex hormones are not HRT because they are not “replacing” anything. The reason a trans person is not producing enough estrogen or testosterone is not a physiological phenomenon; it is purely psychological because their sex doesn’t match the gender in their mind. Calling them hormone disruptors would be more accurate because the intent is to thwart the hormones naturally produced in their body to aid their goal of making their physiological self match their psychological self.