RichTothill

Cancer genomics to make a difference for patients with rare and orphan diseases.

[RichTothill @rtothill]

A big team effort of @GenCancerCentre @PeterMacCC @LindaMileshkin SUPER study collaborators and patients. See our recently published Nature Comms paper https://t.co/MIK5hC8Pdj employing clinical whole genome sequencing for diagnostically challenging #cancer of unknown primary

[RichTothill @rtothill]

Great satisfaction to finally publish this seven years in the making @A5_Adrenal SDHB study involving multi-omic analysis of #pheo #para to understand the molecular basis of metastatic progression and treatment resistance. @PheoPara https://t.co/OXKoVEriky

[RichTothill @rtothill]

Exciting new job opportunity for a talented research assistant to join our team at @UMCCR @UMCCR_RADIO_Lab developing novel cancer diagnostics using cell free DNA. Apply now! https://t.co/wF18cvJh5L

[RichTothill @rtothill]

@AliciaMConway @PeterMacCC @UMCCR @UMCCR_RADIO_Lab @CupAwareness @CUP_Jo @OfficialUoM @UoM_DCS @LindaMileshkin @oncocook Absolute pleasure hosting you here in Melbourne @AliciaMConway. Visit us any time!

[RichTothill @rtothill]

@jorisvandehaar This is really nice work, congratulations! We also found a high number of Vd1/3 gdT cells in a subset of Merkel cell carcinomas with prognostic significance - a rare skin cancer that responds to immune checkpoint inhibitors. https://t.co/on7n507khs

[RichTothill @rtothill]

Today is #NETCancerDay @netcancerday raising awareness for #NeuroendocrineCancer patients around the world. Big shout out to NET and #pheo patient advocacy groups @NECancerAus @PheoPara @CureNETs. Thanks for supporting our research @UMCCR_RADIO_Lab

[RichTothill @rtothill]

@tGaoTeng @UMCCR @KollingINST @PeterMacRes @10xGenomics @NECancerAus @PheoPara We are working on putting together an non-identifying version of the snRNA-seq count matrices for easy sharing. Also the merged bulk tissue data. Should have this very soon!

[RichTothill @rtothill]

Massive team effort to publish our single cell (nuclei) RNA-seq study on #pheochromocytoma and #paraganglioma https://t.co/LPP0KGJHXX. Thanks to all who contributed! @UMCCR @KollingINST @PeterMacRes @10xGenomics @NECancerAus @PheoPara

[RichTothill @rtothill]

Special mention and congratulations to PhD student Atara Posner as first author of the paper!

[RichTothill @rtothill]

Big collaborative effort from our national SUPER CUP program @PeterMacCC @LindaMileshkin and @UMCCR @UMCCR_RADIO_Lab to show how DNA and RNA tests can help resolve a #cancerofunknownprimary diagnosis. https://t.co/seaqicxPhy

[RichTothill @rtothill]

If you are a motivated early career bioinformatics post-doc wanting to explore whole genome sequencing of cfDNA and are interested in translational cancer research this might be the right project for you!

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

JOB OPPORTUNITY: #WholeGenome sequencing of cfDNA in cancer patient blood samples—the project's ultimate aim is to develop a rapid and accessible diagnostic tool for cancers of unknown primary. @UMCCR_RADIO_Lab @rtothill
https://t.co/YyRLUYlw8W

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

JOB OPPORTUNITY: Want to join a team improving outcomes for people with cancer of unknown primary? The @UMCCR_RADIO_Lab Clinical Genomics Project Coordinator is a key role to ensure the successful delivery of this life-changing study. #genomics @rtothill

https://t.co/G6EZaRnRMt

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Just published! Our Pursuit article as a companion to our SUPER-NEXT CUP study launch this week. Thanks to all who made this a great success @kymm_sheehan @LindaMileshkin @UMCCR @PeterMacCC @DrClareFedele Unmasking cancers with hidden identity https://t.co/yOV2vHe44X

[RichTothill @rtothill]

Huge thanks to co-first authors Nick Gherardin, Kelly Waldeck and Alex Caneborg and many others who generously collaborated on this study. γδ T cells in Merkel cell carcinomas have a proinflammatory profile prognostic of patient survival https://t.co/M9sX15MNP4

[Journal for ImmunoTherapy of Cancer @jitcancer]

New #JITC article: Clinical, FDG-PET and molecular markers of immune checkpoint inhibitor response in patients with metastatic Merkel cell carcinoma @Shahneen3 https://t.co/nswsNMtmu5

[Linda Mileshkin @LindaMileshkin]

Excited to have the opportunity to receive MRFF funding to study a new type of PET scan to help improve diagnosis and treatment for patients with Cancer of Unknown Primary (CUP) together with fantastic team incl @UMCCR @rtothill @BowtellLab

[RichTothill @rtothill]

So proud to be working with such talented people on this project and to be receiving this important research funding for #unknownprimary

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

The SUPER-NEXT study to genetically sequence patients w/ cancers of unmet need—providing clearer diagnosis & targeted, personalised treatment options—has received almost $5m MRFF funding, led by @rtothill in collab w/ @LindaMileshkin @PeterMacCC >> https://t.co/hMqpnBz8rU

[RichTothill @rtothill]

@UMCCR @LindaMileshkin @PeterMacCC @VicCompCancerCr @seangrimmond @UniMelbMDHS @UMCCR_RADIO_Lab @GregHuntMP This is a big day for our dedicated SUPER CUP team @UMCCR and @PeterMacCC as we continue to apply innovative genomic methods for CUP patient care in Australia. I’m really blessed to be working with such talented group of clinicians and scientists.

[RichTothill @rtothill]

Nice news article in today’s Age with commentary from our Aussie scientists describing why COVID-19 became so virulent in humans..https://t.co/E5DxvndQ7v

[𝙶𝚛𝚊𝚑𝚊𝚖 𝚃𝚊𝚢𝚕𝚘𝚛 @LordGenome]

Principle of the Abbot #COVID-19 test. “the method is able to amplify RNA without a separate reverse transcription step.“ https://t.co/psAWzuWCZR