Rare Disease Oncogenomics (RADIO) Lab

Working to improve outcomes for patients with rare cancers by discovery, development of diagnostic tests and the application of precision medicine

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

JOB OPPORTUNITY: Want to join a team improving outcomes for people with cancer of unknown primary? The @UMCCR_RADIO_Lab Clinical Genomics Project Coordinator is a key role to ensure the successful delivery of this life-changing study. #genomics @rtothill

https://t.co/G6EZaRnRMt

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Just published! Our Pursuit article as a companion to our SUPER-NEXT CUP study launch this week. Thanks to all who made this a great success @kymm_sheehan @LindaMileshkin @UMCCR @PeterMacCC @DrClareFedele Unmasking cancers with hidden identity https://t.co/yOV2vHe44X

[RichTothill @rtothill]

Huge thanks to co-first authors Nick Gherardin, Kelly Waldeck and Alex Caneborg and many others who generously collaborated on this study. γδ T cells in Merkel cell carcinomas have a proinflammatory profile prognostic of patient survival https://t.co/M9sX15MNP4

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

World Cancer Day 2021: Six weeks with my biopsy - A story of cancer and ... https://t.co/W9PX7bo1RB via @YouTube..hear our very own @rtothill give an overview on clinical genomics data generation and curation and hear him answer some very interesting questions.

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Great to contribute to this important work

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

Research has identified predictors of immune checkpoint inhibitor response in Metastatic Merkel cell carcinoma, and confirmed efficacy and safety in clinical trials—a collaboration between Dr @rtothill @BigDataPatto @UMCCR_RADIO_Lab & @g_auyeung @PrachiBhave6 @PeterMacCC

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

#UMCCRSeminar: Join Prof Sarah-Jane Dawson @TheDawsonLab—of @PeterMacCC & UMCCR—for an overview of her work on liquid biopsy alternatives to tissue biopsies for monitoring cancer changes over time. REGISTER >> https://t.co/VNSkJHHTgP

[IdoAmitLab @IdoAmitLab]

We are in the dark on how the #COVID2019 spreads. Cannot stress more on how critical it is to test, test, test!!! We are working with @Elinav_Lab @EranElinav @WeizmannScience to develop a new technology for MASSIVE testing of #COVID2019. More info here:
https://t.co/KSeWgMsabj

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

RADIO lab head Richard discussing non-conventional gamma-delta T cells in Merkel Cell Carcinoma.
#RareDisease #Cancer @UMCCR

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

#UMCCRSeminar: The @UMCCR_RADIO_Lab’s research has evolved to explore unconventional T-cells—particularly Gamma delta T cells—and has collaborated with @LGMartelotto to undertake #singlecell sequencing to better understand gene expression.

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

#UMCCRSeminar: Dr @rtothill’s @UMCCR_RADIO_Lab is dedicated to translational research of rare and less common cancers. Merkel cell carcinoma is a rare but aggressive cancer with low 5-year survival, and Australia has the highest incidence worldwide. https://t.co/COXRpwI2ES

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

Dr @rtothill's @UMCCR_RADIO_Lab is working to improve outcomes in rare and less common cancers through development of better diagnostic and prognostic clinical tests, targeted treatments, ad predictive markers of therapeutic response. #LorneCancer https://t.co/COXRpwI2ES

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

#LorneCancer: Catch Dr @rtothill and Dr @RosselloFJ in the auditorium 11:10am today, presenting work in single-nuclei RNA-sequencing on rare neuroendocrine tumours & decoding #pancreaticcancer using #singlecell sequencing https://t.co/grEB8EhfbH @LorneCancer

[Collaborative Centre for Genomic Cancer Medicine @GenCancerCentre]

At @LorneCancer? Check out posters from our own Andrew Patterson (@BigDataPatto), @AtaraPosner and Jacek Marzek (@jacol_m) on the A5 Study, cancer of unknown primary, and using RNA-seq data to complement genome-based findings. #LorneCancer #lornecancer2020

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Alex Caneborg explaining how gamma delta T cells are important in Merkel Cell Carcinoma. #lornecancer @UMCCR

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Finding #FACETS really useful for getting copy number from #WGS from the #ratgenome @sloan_kettering
https://t.co/6lNFRJI6hB

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

⁦@BigDataPatto⁩ demonstrating using mutational signatures in RNA-seq as a cancer diagnostic.. proud RADIOlab moment😀

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Also come see Alex Caneborg's poster 'Establishing the Gene Signature of Gamma Delta T Cells in Merkel Cell Carcinoma with Single Cell RNA Sequencing'. He is the alpha of gamma-delta T cells. #AGTA19 @UMCCR 🔥🔥🔥

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Get ready for a pimpin Posner Poster @AtaraPosner at #AGTA19! Atara will be showing off some great work in #CUP at the #UMCCR. You could say it's her signature work 😉🆒🆒🆒 #MutationalSignatures

[Mark Dawson @MAF_Dawson]

Really excited to share our latest manuscript published today describing how chromatin modifiers regulate immune surveillance in cancer - hope you enjoy it!

https://t.co/pIvoNntSJm

[Rare Disease Oncogenomics (RADIO) Lab @UMCCR_RADIO_Lab]

Fantastic meeting today with our consumer group for cancers of unknown primary as part of our SUPER study here at @VCCC @PeterMacCC @UMCCR An inspiration to hear their personal stories and ideas on how we can improve care of CUP patients.