Very pleased to share our latest work on substrate identification of deubiquitylases, led by @VRossio, in collaboration with @PauloLabMS@GygiLab, available @CellChemBiol. Link below is active until July 17. https://t.co/Y4Q2cHHRN8
Want to know more about what defines DUB substrate specificity? Check out new work from the master of in vitro cell biology herself @VRossio, @rwkhms, and @GygiLab! Congrats to all authors on this beautiful characterisation of DUB substrates.
https://t.co/BYAjQnbxXf
Can scientists be taught how to choose good projects?
I took a fantastic class taught by @mfgrp last quarter where the foundational hypothesis is: Yes, they can!
And I continually come back to these core insights as I think about project choice and direction in my 2nd year of PhD:
So, so cool. TEs to the rescue in naked mole rats. Precancerous cells proliferate to quickly for DNA methyltransferase to keep up, resulting in expression of retrotransposons, which triggers interferon response and cell death.
https://t.co/a61QP4Ib3Q
This is your semi-annual reminder that these frigid polar vortex bomb cyclones happen BECAUSE of global warming! Hot N Pacific water pushes the arctic circle air down onto the US, let’s take action. #ClimateAction#ClimateCrisis
Lack of funding for the next generation COVID vaccines, including nasal spray boosters, will slow our progress in providing immunity where it’s needed - at the point of viral entry👃🏼
Thank you @VinGuptaMD@nbcnews for this news coverage!
#mucosalvaccine
https://t.co/fBFBFxnkyj
Science educators searching for a compelling way to teach the importance of understanding how small molecules, macromolecules, and macromolecular assemblies differ: your quest is at an end.
Impactful words by @CarolynBertozzi today on how diversity in her trainees enabled creativity, not playing by the rules, and ultimately the work that built the field of bioorthogonal chemistry. Diverse science leads to better science!
🚨I wrote about ME/CFS (chronic fatigue syndrome). The US has millions of people with it & maybe two dozen docs who specialize in it.
This medical crisis needs urgent attention, esp. now COVID has hugely increased the number of long-haulers. 1/
https://t.co/TxURal8wCK
Very excited to see our new Science paper by my student Sam Wattrus. Macrophages interact with stem cells and determine which clones to selectively amplify or to destroy, providing a quality assurance mechanism for determining which stem cells contribute to adult blood.
There are very few people I’d do this for. But it seems I’m on the train to London to join a very long overnight queue with my dear old Mum.
Here comes a rolling thread about #TheQueue