Ryan Donnelly

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[Rapid Response 47 @RapidResponse47]

.@SecKennedy NUKES @DanaBashCNN:

"I'm not debating this with you."

"Of course you won't. All you know how to do is repeat things that people told you and say, 'Trust the experts!' That's what you did during Covid. Now we know that Anthony Fauci, who was the 'expert,' was lying about everything... now, you're rolling out the 'experts' again to talk about something that you have no personal knowledge of."

[STRIKE @Strike]

"The central bank must be trusted not to debase the currency, but the history of fiat currencies is full of breaches of that trust."

- Satoshi, 2009

[NotKennyRogers @NotKennyRogers]

Just a quick reminder that they arrested this guy for paddleboarding alone in the ocean during Covid while Anthony Fauci had dinner with Jake Tapper and his wife in DC and Gavin Newsome hosted a party with friends in California.

[NPR @NPR]

A new poll finds 40% of respondents believe in a baseless conspiracy theory that the coronavirus was created in a lab in China.

There is zero evidence for this. Scientists say the virus was transmitted to humans from another species.
https://t.co/GDTo2geUng

[Ryan Donnelly @ryandonn28]

Keep going

[Ryan Donnelly @ryandonn28]

@GregFinberg I have wagered on the over

[ol’ stocky ⛳️ @oldstocky]

Ian Fleming’s typical day at his estate in Jamaica where he wrote all his James Bond stories, need to emulate this

[Tom Elliott @tomselliott]

Anthony Fauci, writing in his diary in March 2020, clearly loving life:

"Big front page article abut me appeared in the Washington Post. Very flattering. The situation with my national and international fame is explosive and really unimaginable. It is not hyoperbole [sic] to say that today I am the most famous and talked about person in the country and one of the most recognizable peson [sic] in the world.

"Countless profiles on me in multiple media. I cannot even read all the things that are written abuyt me since I am so busy….seriously. POTUS seems to be enamored of me even though I am taking the spotlight away from him. We are developing a very unique and interesting relationship. The entire secret service corps is coming over to me and chatting. They let me into the first gate without even checking ID."

[Elon Musk @elonmusk]

Next month, every line of code touching the 𝕏 system will be open source and third-party audited.

Only total transparency deserves trust.

[Financial Physics @FinancialPhys]

You need to earn $7320 per week

to equal the same spending power a full time gas station attendant had at minimum wage in July 1971

[Ryan Donnelly @ryandonn28]

@KevG163 Incredible

[Muskonomy @muskonomy]

NEWS: Elon Musk rejects the far right label in an exchange with The Economist

"I support the normal people. What you call the far right, falsely."

He challenged the interviewer to say what is extreme about 3 positions.

"Here are the principles and tell me which of these sound terrible. That we should have secure borders, that we should have safe cities, that we should have sensible spending. Which of those three are far right fringe?"

Elon then turned on the framing itself.

"I would like to just admonish you and the media for the absurd characterization of the far right. It is false and misleading and nonsense."

He asked that the exchange survive the edit. "Please keep this part in."

Elon said the same speeches get judged by who delivered them, describing a habit of reading Obama and Clinton speeches to people and telling them Trump said it. He named Rupert Lowe as an example of who he means by normal people.

(Source: The Economist, July 2026)

[Ryan Donnelly @ryandonn28]

@ESPNNFL No

[Josh Chambers @JoshChambers]

Sean McVay on what has become non-negotiable when evaluating players:

“There are certain things that have to be non-negotiables. What’s your football character like? I think that more than anything, especially because of some of the things I’ve gone through where I look back and say, ‘Man, I did not like the kind of leader or the caliber of person I was. I was fragile. I wasn’t resilient. The game honors toughness, but I think life and the game honor toughness, both mentally and physically. How many different ways can we measure that mental resilience?"

"What have they been through, and how did that shape who they’ve become in the midst of the journey?”

“When you go through each guy and have a personal message of appreciation and gratitude for him, the consistent theme is that everybody who has had any sort of success has experienced some adversity. Maybe when you’re in it, you don’t see the light at the end of the tunnel, but if it shapes you and callouses you the right way, growth demands that discomfort.”

“You don’t punish people who haven’t been through adversity, but I also think it’s important for guys to know, ‘We’re in this shit with you, too. Let’s build a relationship.’”

“Chris Petersen always used to say to me, ‘It’s really important that all our players know they’ll never meet the enemy on the sideline.’ I’d like to think the connection, the camaraderie and the enjoyment of each other’s success are what you see when you watch our group play. That’s the type of people we’re trying to identify.”

[David Sacks @DavidSacks]

Cernovich is right that AI + Big Tech could easily turn into Big Brother. But what’s the alternative to living off the grid or in the Panopticon? The third option is to run your own AI on your own hardware, retaining data sovereignty. That’s why open source matters. It’s software freedom.

[The All-In Podcast @theallinpod]

Friedberg: New study shows enzyme reverses skin age from 70+ years to 31

Chamath: That’s a $2T market.

Did Scientists Just Discover How to Reverse Skin Aging!?

“CML is kind of the predominant molecule that gets formed in this extracellular matrix that's driving aging, and nothing breaks it down.

So these scientists set out to try and create an enzyme, an enzyme is a protein that breaks something down, that can break down CML.

And so these guys kind of went out and they took the target, which is CML, and tried to figure out, ‘Okay, how do we actually degrade CML, clear that extracellular matrix, and reverse aging?’

They started to test it on the proteins that we would find in our body, casein, collagen, retinal proteins, which are in your eye, hemoglobin, and they were able to get rid of 52 to 97% of the CML, just degrade it away.

And then they found several sites where they were able to degrade over 90%.

And then they took actual human skin from elderly patients that had donated their skin, and they put this enzyme onto that skin, and they were able to eliminate 55% of the CML on the skin, basically reverse the skin's age down to the age of a 31-year-old, this is from greater than 70-year-old patients, just by putting this enzyme on the skin.

And so it's kind of a groundbreaking demonstration of combination of AlphaFold, what's called directed evolution, where you change the order of the DNA that changes the structure of the protein to test different proteins, do high throughput screening, and ultimately make a novel protein that doesn't exist in nature today that can do something pretty profound for human health.”

Chamath:

“It will be a trillion-dollar market. If you can create a cream…”

Friedberg:

“I mean, dude, if you could put this enzyme literally on your skin and have it absorb in…”

Chamath:

“Game over. That alone is $2 trillion.”

[Ryan Donnelly @ryandonn28]

@TheHoopCentral My point guard

[Jeremy @jeremyct]

My wife and I got into it last night about the grocery bill.

I pulled up an old Target order from February 2020.

28 items. $64.50.

Added every single one back to the cart just to see.

$158.30.
Same 28 items. Same store. Same cart.
$93.80 more.

In five years.
We didn’t buy more.
Didn’t upgrade anything.
Didn’t add a single extra item.

Just needed the same things we always needed.

They told us inflation was transitory. They told us it was under control. They told us the economy was strong.

Our cart didn’t get any of those memos.
145% increase in five years.

Not one member of Congress has looked at a grocery receipt in decades.

And it shows.

[Ryan Donnelly @ryandonn28]

@cobie @blknoiz06 @heart_ 🫡