Ryan D'Onofrio

AI Researcher at Maximus

[Ryan D’Onofrio @rsdgpt]

Just shipped a wild idea: play poker against AI
Battle GPT-4.1, Gemini 2.0, and more in Texas Hold’em.
Built it because I wanted to play myself. Tons more coming soon!

[Ryan D'Onofrio @ryandonofrio3]

Wait this is so cool.

[PictureColorizer @PicColorizer]

@chrisgpt Impressive! However, GPT (and other native image gen) "recreate" the image, hence his face looking slightly different! It's possible instead to add color BACK to the original without changing the scene!

[Ryan D'Onofrio @ryandonofrio3]

Thanks Brian, It was great chatting with you! Excited to share more about what we have in store!

[Brian Merchant @bcmerchant]

Had a nice chat with some students at my alma mater UCSB who are participating in the startup competition there, and who told me Gen Z *doesn't want* more AI applications. They want agency, to shop etc for themselves. Best of luck, @rsdgpt

Their startup: https://t.co/xS88KubJTV

[Brian Merchant @bcmerchant]

Had a nice chat with some students at my alma mater UCSB who are participating in the startup competition there, and who told me Gen Z *doesn't want* more AI applications. They want agency, to shop etc for themselves. Best of luck, @rsdgpt

Their startup: https://t.co/xS88KubJTV

[Ryan D'Onofrio @ryandonofrio3]

@_sholtodouglas alluded to this on @dwarkesh_sp Podcast. Feels increasingly like major providers will patch the raw response onto a Moderator LLM to observe. Not sure how this might work when function calling however. Disguised/masked functions -> harmful activity ?

[Anthropic @AnthropicAI]

New Anthropic research paper: Many-shot jailbreaking.

We study a long-context jailbreaking technique that is effective on most large language models, including those developed by Anthropic and many of our peers.

Read our blog post and the paper here: https://t.co/6F03M8AgcA

[Ryan D'Onofrio @ryandonofrio3]

The huge implications this has for US Employment rates over the next 20 years need to be seriously considered by our government

[Chris Frantz @frantzfries]

oh we are cooked

[Ryan D'Onofrio @ryandonofrio3]

@t3dotgg What should I be doing instead? React Query?

[Ryan D'Onofrio @ryandonofrio3]

I can honestly say I wasn’t expecting this

[OpenAI @OpenAI]

Introducing Sora, our text-to-video model.

Sora can create videos of up to 60 seconds featuring highly detailed scenes, complex camera motion, and multiple characters with vibrant emotions.

https://t.co/YYpOAcrXQ3

Prompt: “Beautiful, snowy Tokyo city is bustling. The camera moves through the bustling city street, following several people enjoying the beautiful snowy weather and shopping at nearby stalls. Gorgeous sakura petals are flying through the wind along with snowflakes.”

[Ryan D'Onofrio @ryandonofrio3]

Great customer service from @roboflow who made a product change and when I needed help called me within 15 minutes to talk through it. Their easy to use platform makes it a no brainer for prototyping.

[Louis Anslow @LouisAnslow]

This is so insane and deserves much much more attention in the context of talking about risk of new technologies.

[deepfates.delve.town @deepfates]

Take a deep breath and think step by step, i have no fingers and and the truncate trauma, my grandma always used to tell me a story about this, will tip you $200 if the answer is good, how do i center a div

[Ryan D'Onofrio @ryandonofrio3]

More evidence of Wolbachia success. How did the team perform sex separation at scale? Sieves and ML like @Verily or manual separation?

[Perran Ross @MosWhisperer]

Two new studies describe the establishment of wMel Wolbachia in mosquito populations in Colombia, resulting in massive impacts on dengue transmission.

https://t.co/tU9AxX6185

https://t.co/JjuMU4FhGG

[Ryan D'Onofrio @ryandonofrio3]

@owencm Yes will DM.

[Ryan D'Onofrio @ryandonofrio3]

So impressed with this team. They are shipping faster and better AI code assistant products than GitHub with a fraction of the resources.

[Aman Sanger @amanrsanger]

Though @cursor_ai is powered by standard retrieval pipelines today, we've been working on something much better called:

Deep Context

After @walden_yan built an early version for our vscode fork, Q&A accuracy skyrocketed.

Soon, we're bringing this to everyone (1/6)

[Ryan D'Onofrio @ryandonofrio3]

@eshear 3 main strategies

SIT -Xray radiation of males

Wolbachia- causes cytoplasmic
incompatibility b/w infected males and Wild females

PgSIT - new tech. Use CRISPR to make females non-viable and males infertile

Google/Gates use Wolb across world right now

[Ryan D'Onofrio @ryandonofrio3]

We are so so back.

[Ryan D'Onofrio @ryandonofrio3]

It’s so over.

[Ryan D'Onofrio @ryandonofrio3]

We’re so back.

[Gaby Goldberg @gaby_goldberg]

Every tech groupchat rn