@fly91_IN Request for rescheduling of my flight
PNR: M22ALX
Flight Number: IC3306
Current Travel Date: 19 June
VGA TO HYD
Current Timing: 17:40 hrs – 18:50 hrs
I would like to change my booking to the FLY91 flight operating on 20 June on the same time 17.40-18.50 on 20th june
🩻Contrast-induced AKI:
one of the biggest myths still shaping clinical decisions
For decades we were taught:
👉 “Contrast damages the kidneys”
👉 “Avoid CT with contrast in CKD”
👉 “Hydrate, protect, delay imaging if needed”
But what if… most of this is wrong?🤔
->The uncomfortable reality
Modern evidence shows:
👉 Low-osmolar contrast rarely causes true nephrotoxicity
👉 Even in CKD, AKI, and ICU patients
👉 The risk is often overestimated—or nonexistent
So where did the fear come from?
📍 1950s high-osmolar contrast (actually toxic)
📍 Poorly controlled observational studies
📍 “Creatinine rise = contrast injury” assumption
👉 Correlation became causation
👉 And the dogma stayed
⚠️What recent data tells us
✔ No difference in AKI rates with vs without contrast
✔ No benefit from bicarbonate, NAC, or aggressive hydration
✔ Even ICU and AKI patients show no worsening outcomes
->Translation to real life
👉 The patient was going to develop AKI anyway...Not because of contrast!!
->The real problem: “Renalism”
👉 Avoiding necessary imaging
👉 Delaying diagnosis
👉 Choosing inferior tests
And that leads to:
❌ Missed PE
❌ Delayed sepsis source control
❌ Worse outcomes
->Clinical mindset shift
Instead of asking:
👉 “Will contrast harm the kidneys?”
We should ask:
👉 “Will NOT doing the scan harm the patient?”
->Who still deserves caution?
✔ eGFR <30
✔ Severe hemodynamic instability
✔ Multiple nephrotoxins
Even then:
👉 Optimize volume
👉 Minimize dose
👉 Don’t delay critical imaging
🤓Bottom line
✔ Contrast nephrotoxicity exists… but is rare
✔ The fear is bigger than the risk
✔ The harm of NOT imaging is often greater
In critical care
👉 We don’t treat creatinine
👉 We treat patients
And sometimes…
👉 The most dangerous thing is NOT the contrast
👉 It’s hesitation.
📃Reference
Florens N, Demiselle J.
Kidney360 7: 445–449, 2026. doi: https://t.co/CWzi7WC9Wx
💥 #CriticalCare Nephrology Myths vs Reality🫘
📸A brilliant snapshot busting 10 persistent false beliefs in #AKI & #RRT —and what the evidence actually tells us
Essential read for every ICU & nephro clinician
🔗https://t.co/WAlObLYu6B
#NephroTwitter#ICU#RRT#MedEd
Zigakibart is a humanised monoclonal antibody for treatment of IgA nephropathy.
Dr Jonathan Barratt discussed the phase 1/2 trial results of Zigakibart at #isnwcn
Eagerly waiting for the phase 3 BEYOND trial results.
TTS Education Committee in collaboration with the Indian Society of Nephrology presents a Webinar on - Urinary Tract Infections after Transplantation.
#nephtwitter
Friday, Aug 23, 2024 - 09:00 AM (Montreal Time), 6.30 PM IST.
Link to Register 👉 https://t.co/Y5j6kSVo7u