Roy Choudhury Lab

Assistant Professor, Arkansas Children's Research Institute, University of Arkansas for Medical Sciences

[Roy Choudhury Lab @SamratRoyChoud6]

We are presenting in AACR 2026.
Abstract 3496: Epigenetic repurposing by CBFA2T3-GLIS2 reveals a druggable DNA methylation axis in high-risk pediatric AML vulnerability in pediatric AML https://t.co/iirLoyPPsF

[Roy Choudhury Lab @SamratRoyChoud6]

New article from lab "DNMT3B Controls Enhancer-Linked Chromatin and Cell Cycle Networks in Acute Myeloid Leukemia" https://t.co/lpfRrvWkvG #mdpicancers via @Cancers_MDPI

[AACR @AACR]

Stephen Mack, Eleni Tomazou, Brian Rubin, Gabriel Boyle, and Samrat Roychowdhury discussed "Gene Regulatory Mechanisms of Oncoproteins" in a plenary session at the AACR Special Conference on Fusion-Positive Cancer. #AACRfusion26 @TomazouLab @SamratRoyChoud6

[Roy Choudhury Lab @SamratRoyChoud6]

New in Genes & Diseases!
Enhancer methylation in CBFA2T3-GLIS2 AML drives oncogenic transcription & reveals epigenetic vulnerabilities.
https://t.co/CRveRYwllf
#Epigenetics #Leukemia #AML #PediatricCancer

[Roy Choudhury Lab @SamratRoyChoud6]

Our recent findings uncover a noncanonical role of DNA methylation in driving MED12 overexpression in AML—showing that TSS-proximal hypermethylation can support, not silence, oncogenic transcription. https://t.co/ulXJVM9pU3

[Roy Choudhury Lab @SamratRoyChoud6]

I'm delighted to share my short piece of fiction, The Forsaken Thread, published in UAMS's online magazine Medicine and Meaning. https://t.co/yAag9wbwef

[Roy Choudhury Lab @SamratRoyChoud6]

Honored to receive an honorable mention for the Mehta Award for Creative Writing for my short fiction, The Forsaken Thread https://t.co/z7020tB0wt

[Roy Choudhury Lab @SamratRoyChoud6]

As this busy summer unfolds, we're delighted to mark an important transition: Pritam, our lab's inaugural postdoctoral fellow, is graduating to his next role. We extend our warmest congratulations and best wishes for his future success.

[Roy Choudhury Lab @SamratRoyChoud6]

Great tool indeed! https://t.co/VIu8QcsVE6

[Roy Choudhury Lab @SamratRoyChoud6]

A great talk by Dr. Samantha Kendrick on " the role of DNA G-quadruplexes in facilitating mutations in lymphoma" at the ACRI Monthly Research Seminar Series. @uamscancer @archildrens @UAMS_Biochem

[Roy Choudhury Lab @SamratRoyChoud6]

An eventful summer for the lab with students from postdoc to elementary school level.

[Roy Choudhury Lab @SamratRoyChoud6]

@varshneylab @qinwei007007 @NatureComms @OMRF Congratulations!

[Elizabeth McKenna @ElizSMcKenna]

Now online in @CD_AACR: A Functional Survey of the Regulatory Landscape of Estrogen Receptor-Positive #BreastCancer Evolution - Iros Barozzi, Giorgio Galli, @MagnaniLab_ICR and colleagues @MedUni_Wien @Novartis @ICR_London https://t.co/CAsVD7fsNh

[Roy Choudhury Lab @SamratRoyChoud6]

Our new study reports the unique DNA methylation landscape in SET-NUP214 positive leukemia
https://t.co/FhZR3E8PX8
@uamscancer @archildrens #CancerResearch

[Roy Choudhury Lab @SamratRoyChoud6]

Excited to share that my rare cancer research received a "Concept Award"! Motivated to contribute to fighting the deadliest pediatric leukemia and thankful for the support. https://t.co/cu4j6SvBMw
@CDMRP @uamshealth @uamscancer @archildrens

[National Cancer Institute @theNCI]

Announcing the Childhood Cancer Clinical Data Commons (C3DC), a new tool for #ChildhoodCancer researchers. This web app includes harmonized childhood cancer demographics and phenotypic clinical data. Check it out today! https://t.co/8wXp8NNlnX #Data4ChildhoodCancer

[Roy Choudhury Lab @SamratRoyChoud6]

Our lab will be presented at the AACR Annual Meeting 2024.
Abstract 1733: SET-NUP214 rearranges the DNA-methylation landscape to upregulate the HOX-gene cluster in acute myeloid leukemia https://t.co/RmeMN9jmkt
@uamscancer @archildrens

[Roy Choudhury Lab @SamratRoyChoud6]

A great collaborative work with Dr. Sarah Blossom is now out!!
Trichloroethylene metabolite modulates DNA methylation-dependent gene expression in Th1 polarized CD4+ T cells from autoimmune-prone mice https://t.co/crUeRpcezN
@Dr_sarahblossom, Stephanie Byrum

[Roy Choudhury Lab @SamratRoyChoud6]

Abstract P16: CBFA2T3-GLIS2 fusion leads to a distinct DNA methylation enhancer landscape in pediatric acute myeloid leukemia https://t.co/Wmlcc5V5Ze
@uamscancer @archildrens

[Itai Yanai @ItaiYanai]

I want to tell you a story about a recent discovery that we made in the lab, because we often argue here whether it’s the data or the hypothesis that comes first. In the case of this discovery, it was definitely the data that showed us something that we completely didn't expect.