Szu-Hsien Sam Wu

CRISPR, Organoids, genetics, imaging, cancer.
Endurance runs. 🏃‍♂️

[Andreas E. Moor @AndreasMoor]

My lab at ETH has an opening for a Scientist in Antibody & Nanobody Drug Discovery (workspace in Basel, Switzerland): https://t.co/mfm7PpHJEj Please apply if suitable or RT, thanks!

[Jens Puschhof @JensPuschhof]

Do you want to take a leading role in shaping a research group on functional cancer microbiome work, including coordination of an @ERC_Research grant and national consortium? Join our @EMIL_DKFZ team in Heidelberg as Staff Scientist! Details: https://t.co/8YEoxtUrAM
Pls Retweet😀

[Szu-Hsien Sam Wu @samwu202]

@ChongLi_cl @Knoblich_lab @IMBA_Vienna This is so great! Congratulations, Chong! 🥳

[Andreas E. Moor @AndreasMoor]

How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. https://t.co/oWFn3Hfj8M 🧵

[Szu-Hsien Sam Wu @samwu202]

@joonsunlee Thank you Joonsun 😀

[Szu-Hsien Sam Wu @samwu202]

Two personal announcements:
1. My PhD work was just published in Nat Comm (https://t.co/RSyGXGLCxT): a mosaic knockout tool with multicolor reporter readout. Big thanks to all the authors and colleagues at the VBC who contributed to the work & gave advice.

[Szu-Hsien Sam Wu @samwu202]

@arnese_renato Thank you Renato!!

[Szu-Hsien Sam Wu @samwu202]

@JY_Park102 Thank you so much Jin Young!

[Szu-Hsien Sam Wu @samwu202]

@chandrrrika Thanks a lot Chandrika!

[Szu-Hsien Sam Wu @samwu202]

@JensPuschhof Thank you so much Jens!

[Szu-Hsien Sam Wu @samwu202]

Many thanks to my family, friends and colleagues who supported me along the way. I look forward to all the discoveries in and outside of the lab 😊

[Szu-Hsien Sam Wu @samwu202]

2. I started my postdoc in the Moor lab (@moorlab) at D-BSSE, Basel (after spending a year being home & in the Taiwanese army). I am very excited to work on multidisciplinary projects with everyone here - including genetic screens, single cells & spatial-omics.

[Catarina Martins Costa @catarinacsmc]

We're at the cover of Cell Stem Cell.
We're at the cover of Cell Stem Cell.
We're a-
(I can barely believe it. 🤯)

We found out why some people are born without the main interhemispheric bridge. 🧠

👏 to @PhDexheimer for this beautiful illustration of the corpus callosum.

[Erik Vrij @E_Vrij]

We are really excited to share our findings on monochorionic twinning in human blastoid embryo models https://t.co/6VUCshmitj, shedding light, finally, on the formation of identical twins. @MERLN_UM @Dorian_Luijkx https://t.co/x9jzpYjhci

[Catarina Martins Costa @catarinacsmc]

Happy #Oct4 with some beautiful stem cells 💙🧡
Can you spot the dividing ones? 👀🦋

[Szu-Hsien Sam Wu @samwu202]

@catarinacsmc Congratulations Catarina, very well deserved!! 🥳

[Will Ratcliff @wc_ratcliff]

I’m delighted that our paper on the Multicellularity Long Term Evolution Experiment (MuLTEE) has, at long last, been published. This paper establishes the foundations of what I’d like to work on for the rest of my career. 1/25

Free, full access link: https://t.co/lWh33eHQrf

[Catarina Martins Costa @catarinacsmc]

😶‍🌫️🤩 It's out!
So happy to share a big piece of my PhD work with the world. 🧩

Using human neural #organoids, we investigated corpus callosum agenesis, a disconnection between the two #brain hemispheres. 🧠

What we found was surprising and exciting... Curious? 📃 👇

[The Knoblich Lab @Knoblich_lab]

📣 Preprint alert!
Check out our latest story, led by @catarinacsmc.

The corpus callosum safeguards interhemispheric communication in the human brain.

𝘈𝘙𝘐𝘋1𝘉 mutations cause agenesis/absence of the CC.
We wanted to know why. 🤓

🧵1/9
https://t.co/RwkEOBpf31

[Szu-Hsien Sam Wu @samwu202]

We are always thrilled when an idea comes into reality. Hopefully we can share this new technology soon. #ICON

[The Koo Lab @koo_lab]

Sam and I introduced the SCON method for easy conditional KO. He made a new conditional intron system, named ICON. When targeted to Leptin, we saw the ob/ob phenotype. ICON works in the opposite way of SCON, so initially KO that can be reverted to WT upon Cre activation.
#Koo_lab