Yet another study showing high discontinuation rate of both semaglutide and tirzepatide up to 50% at 1 year in the real world.
Top discontinuation reasons included:
• Side effects (36%)
• Logistical challenges (24%)
• Cost (23%)
• Shortages (11%)
• Inadequate weight loss (7%)
Excellent talk by Dr. Satya Dash at #ENDO2025
@metabolic_knife@ZaherToumi@rvcohen@babudayyeh agree. In my case series, I have few cases of Sleeve, precisely because I provide a lot of information about what Bariatric Surgery is and its long-term goals. My previous question was about the increase in cases of intestinal diversions associated with Sleeve.
[From the perspective of a simple obesity medicine physician]
🚨Metabolic surgery remains the most effective treatment for obesity.‼️
👉🏻Greater efficacy and durability, better comorbidity management, higher comorbidity remission rates, only treatment with reliable data for ⬇️ in adiposity-related MACE, cirrhosis, ESRD, cancer, and mortality.
What’s more? It’s more cost-effective than newer medical therapies.
Simply, surgery is grossly underutilized. If you know the literature on obesity, this is the only conclusion you can make.