Just wrapped up an amazing experience at #AHA24 in Chicago! ๐ซ๐ฌ It was an honor to present my cardiovascular research! ๐ฅณ
A huge thanks to Denisa Wagner, @DDuerschmied and @LukasHegerMD for their support! Excited for future conversations! ๐๐ป #Cardiology#Innovation#Research
๐ Exciting News: our latest paper from Denisa Wagner's lab (@BostonChildrens@harvardmed) is out now. My first first-author paper, shared with @LukasHegerMD !
Neutrophil NLRP3 inflammasome aggravates myocardial infarction. Huge thanks to all coauthors!
https://t.co/j9TWkiXS0m
Extremely happy to share that our first paper with Denisa Wagnerโs lab (@BostonChildrens & @harvardmed) is now published! ๐ฅณ Spearheaded by @LukasHegerMD we found that selective inhibition of PAD4 prevents inflammation-mediated HF.
Thanks to our contributors!
Check it out! โฌ๏ธ
Immunotherapy for cardiovascular disease: Selective inhibition of Protein Arginine Deiminase 4 (PAD4) an enzyme comprehensively involved in neutrophil activation and NET release with an orally available inhibitor (JBI-589) prevents the development of heart failure in murine inflammatory arthritis with reduced neutrophil infiltration, NET deposition and biomarkers of thromboinflammation in the myocardium. @LukasHegerMD
https://t.co/HrCeBbleqr