Rapid and sustained antidepressant effects of vaporized N,N-dimethyltryptamine (DMT)...
Small, non-blinded, study but impressive results nonetheless...
All 14 clinically depressed subjects received DMT (>96% pure isolated from Mimosa hostilis root bark -- none of this fancy expensive $7,000/gram pharma-grade nonsense), vaporised in two dose sessions 90 min apart:
A 15mg "safety" dose followed by a 60mg therapeutic dose while listening to music for 15 min, followed by 7 min of silence, and finally a 30 min integration session with a psychiatrist.
And that's it. One session on one day...
By the 1st day after dosing, subjects achieved a clinical response rate of 79% and a remission rate of 71%...
At day 7, the response rate peaked at 86%. In the 3rd month, there still was a significant reduction, with 57% of patients remaining in the response range and 36% in the remission range...
For comparison, "the SYNAPSE study with esketamine (plus oral antidepressants) achieved a 32% remission rate after 74 days of multiple dosages, whereas our study reached 35% remission after 84 days with a single-day intervention."
Suicidal ideation (SI) scores also dropped dramatically and in a sustained manner...
DMT is magic...
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