Seth Ari Sim-Son Hoffman

Infectious disease doc/researcher @Stanford • Research to benefit the under-served • 🇺🇸=🇺🇦x🇲🇾

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

I am thrilled/humbled to announce I received an @NIH/@NIAIDNews K23 to use serologic/genomic/modeling methods to evaluate an RCT of #climate-sensitive comprehensive WASH interventions on typhoidal Salmonella transmission - 1 month into being a new parent too! 🤩#IDtwitter ...🧵/1

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

@StanfordCIGH @Stanford @Stanford_ID @Stanford_Med_ID @StanfordMed @StanfordDeptMed @CEPIvaccines @Blueprintbio @StanfordPath @ASMicrobiology https://t.co/dkPv7cXGd5

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

Really pleased to finally get this one out there! Happy Holidays and Happy 2026!

[Abraar Karan @AbraarKaran]

Our latest article in ASM Clinical Microbiology Reviews: “One Confirmed and One Potential Human Case of Influenza A(H5N1) Detected Through an Expanded Subtyping Protocol”.

In this work, we show how an expanded influenza subtyping protocol identified a confirmed and a potential human #H5N1 case that may otherwise have been missed under conventional approaches.

https://t.co/LxxOgKQXLP

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

@StanfordCIGH @Stanford @Stanford_ID @Stanford_Med_ID @StanfordMed @StanfordDeptMed @CEPIvaccines @Blueprintbio @StanfordPath @ASMicrobiology

[Abraar Karan @AbraarKaran]

Our latest article in ASM Clinical Microbiology Reviews: “One Confirmed and One Potential Human Case of Influenza A(H5N1) Detected Through an Expanded Subtyping Protocol”.

In this work, we show how an expanded influenza subtyping protocol identified a confirmed and a potential human #H5N1 case that may otherwise have been missed under conventional approaches.

https://t.co/LxxOgKQXLP

[Stanford Health Care @StanfordHealth]

An infectious disease specialist at Stanford Medicine shares five things families should know about childhood vaccines.
https://t.co/DYyWHW9KmI

[Carlos del Rio @CarlosdelRio7]

The Role and Safety of Aluminum Adjuvants in Childhood Vaccines @AmerAcadPeds https://t.co/OJlwCXdo1Q Aluminum-containing vaccines provide clear benefits, with risks largely limited to transient local reactions and no systemic toxicity signal.

[Edward Nirenberg 🇺🇦 @ENirenberg]

New post from @AmerAcadPeds concerning our recent Special Article:
https://t.co/CSC4bsruFE

[Edward Nirenberg 🇺🇦 @ENirenberg]

I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines. We review the evidence base for key safety concerns and offer guidance for communication with caregivers.

https://t.co/cRl39isFIr

[Abraar Karan @AbraarKaran]

Marburg virus outbreak in Ethiopia, the first ever in this country.

Over the past 5 years, multiple countries have had their first #Marburg outbreaks including Rwanda, Guinea, Equatorial Guinea, Tanzania and Ghana.

We have been studying Marburg spillover for the past 2 years in East Africa through @StanfordKingCtr funding @StanfordMed @StanfordCIGH

While there is better detection now than in decades past, it also seems that spillovers are becoming more common potentially due to other factors including more human-bat interfacing and increased stressors on bats.

https://t.co/F2JxvHOlUA

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

Awesome work Megan and @kathleen_neuzil 🥳 @UMCVD

https://t.co/EaF52xBXnO

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

@dieworkwear @threadreaderapp unroll

[Abraar Karan @AbraarKaran]

Not surprised to see the 'Governors Public Health Alliance' formed by 15 Democratic state governors. Public health fragmentation is underway in the United States because there doesn't seem to be another path forward at this time. We saw this happen already with immunization guidance changes on the west coast and Florida. There are clear issues here, the most obvious being that large unvaccinated populations still pose a risk to those without adequate immunity as it relates to infectious diseases. State borders won't protect you here. This includes infants; elderly; and many in between, including those with cancer and other immunocompromising situations.

[EA Forum Posts @EAForumPosts]

"Funding needed to preserve critical malaria vaccine research" by Seth Ari Sim-Son Hoffman (@SethAHoffmanMD)

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

@han_francis @ENirenberg Fundamentally different antigenic target, whole parasite versus single protein target (CSP; target for RTSS “Mosquirix” & R21). Can protect against infection (meaning use case for elimination), while RTSS/R21 only provide protection against disease (still important!)

More info:

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

@NIAIDNews #DuffyLab & USTTB Mali study to optimize dose of #MalariaVax for future #Maternal studies.

tldr: @sanaria_inc PfSPZ vax SAFELY REDUCED parasitemia and clinical malaria for 2 seasons (without boosting) and FERTILITY INCREASED!

https://t.co/McozBMnsTh

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

@NathanLo3579 🎉🎉🎉

[Stanford Department of Medicine @StanfordDeptMed]

Congrats to #StanDOM's Nathan Lo (@NathanLo3579) on being named a @theNAMedicine Emerging Leader! As a 2025-2028 Scholar, he'll join top early-career minds advancing health & medicine nationwide. https://t.co/ucdgvqp2oF

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

🙏🙏🙏

[Edward Nirenberg 🇺🇦 @ENirenberg]

(1/2) Hi, everyone.

I know many people have been horrifically affected by the funding cuts to science. Sanaria, the company I am consulting for, has produced unprecedented progress in a highly effective malaria vaccine and is in major financial jeopardy because of these cuts.

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

Sanaria reports positive initial safety results for groundbreaking PfSPZ-LARC2 malaria vaccine, via @EurekAlert!

https://t.co/rt9Rb4T8dQ

@sanaria_inc @seattlechildren @UMCVD @UMmedschool @MalariaNoMore @FightingMalaria @ALMA_2030 @beatmalaria @StanfordCIGH

[Seth Ari Sim-Son Hoffman @SethAHoffmanMD]

🎉 Exciting news! #malaria @MalariaNoMore @ALMA_2030 @PAlonsoMalaria @FightingMalaria @MalariaVaccine @gatesfoundation @BillGates @ASTMH @IDSAInfo

[Sanaria Inc. @sanaria_inc]

Sanaria Reports Positive Initial Safety Results for Groundbreaking PfSPZ-LARC2 Malaria Vaccine
https://t.co/aat7aIeWhT

[Moogdho Mahzab @moogdho_mahzab]

So happy and excited to share that our paper on air pollution from brick kilns in Bangladesh is now published in Science! Even more exciting—it’s on the cover! Huge congratulations to our amazing team of co-authors. So proud to be part of this incredible work!

[Edward Nirenberg 🇺🇦 @ENirenberg]

Let's go through all the ways this comment is inherently deceitful.

If you go through the entire recommended childhood vaccination schedule, children receive about 4.4 milligrams of aluminum salts in the first 6 months of life.

What does that mean?🧵