🚀New preprint w/ @roberto_amv: We used chemogenetics to precisely control mitochondrial H2O2 in skeletal muscle in vivo. This exposes a dose-dependent sequence: translation suppression → proteolysis → denervation-like → degeneration @tejensen23 https://t.co/5m7UsAeMnl
Thrilled to share our new study from the @tejensen23 lab showing, for the first time, that mitochondrial H₂O₂ is sufficient to trigger muscle wasting signatures and suppress protein synthesis. Huge thanks to @MuscleBiology and everyone involved!
https://t.co/W5ntl79CHY
Our most comprehensive review ever! With twiterless Amira Klip and Philip Bilan. #nexs
A Comprehensive View of Muscle Glucose Uptake: Regulation by Insulin, Contractile Activity and Exercise | Physiological Reviews | American Physiological Society https://t.co/JglfXP3Q3T
Our new paper in Redox Biol showing that insulin stimulation of skeletal muscle surprisingly does not detectably increase the ROS H2O2 using state-of-art methods in different models including humans, but in fact causes a selective reductive shift
https://t.co/w8mFdR5Vbu
Excited to share our latest publication with the Thomas Jensen team @sgallero_! Grateful for the great support from @MuscleBiology and @tejensen23."
"Exploring NADPH oxidases 2 and 4 in cardiac and skeletal muscle adapta... https://t.co/72yJaZbpqz "
Had an incredible time at the @SFRR_Europe annual meeting last week. 🇹🇷 The event was packed with insightful talks and lots of fun. Truly happy and honored to received one of this year's Young Investigator awards. Special thanks to @tejensen23’s research group for the support 🤩.
SFRR-Europe Istanbul,Turkey 5-7 June 2024 - Celebrating our ECR award winners at a special Gala dinner during a Bosphorus cruise, supported by SFRR-E, Oxygen Club California and Elsevier @SFRBM@SFRRAustralasia @elsbiomedchem @Dr_Emrah_Eroglu@benbedphar
💪 What are the unresolved questions in the regulation of skeletal muscle #insulin action by #reactiveoxygenspecies? 🔥 Carlos Henríquez-Olguín et al. discuss in this latest Review in FEBS Letters:
➡️ https://t.co/sabqGS1XRQ
@MuscleBiology
Attending the @SFRR_Europe annual meeting? Come say hi! 👋 Visit @sgallero_ at Poster PII-B92, catch @roberto_amv's short talk on Thursday at 10:45, and don't miss my invited talk on Friday at 9:40. Expect insights on molecular metabolism, biosensors, and redox physiology.
Did you ever wonder how glucose escapes cellular metabolism when taken up by a gut cell, liver cell or kidney cell and is released to the blood as glucose rather than being metabolized in the cell?
https://t.co/WYyBL47T0v
2y research assistant position (master degree or equivalent) on international collaborative project with me and Christine Allen, Toronto, to test temperature-sensitive liposomes for muscle drug-targeting in mice🐀. Please help me spread the word 🙏 https://t.co/2SldtKeLcj
First rising star episode now online
Great chat. Thanks @MuscleBiology
-Challenges he’s had
-Acute (exercise) vs chronic (disease) increases in ROS
-Exercise and antioxidant defense
-Should supplement antioxidants?
YouTube (https://t.co/R8XwEHBl31), Apple Podcasts, Spotify etc
Looking forward in 2 days to the first rising star interview. Future who’s who researchers.
Dr Carlos Henríquez-Olguín from the University of Copenhagen, Denmark. He’s already winning awards.
Discussing his background and reactive oxygen species and exercise.
Any questions?
We’ve had an exciting week in Denmark! First, we hosted a successful PhD course in Køge. Then, as part of our August Krogh Club, we held a wonderful Mini Symposium at home in Copenhagen. A big thanks to everyone involved! Now it’s time for summer holidays. #MuscleCPH2023@NEXSKU
Networking and learning new transferable skills on 4th day of #MuscleCPH2023. Volley, Kubb, Twerk lesson (guess the PIs🤣) and late-night Karaoke - I want it that way🎤🎵 #Myoparty