Excited to announce that my first-author paper is out in @MolSystBiol! Systems-level analysis in C.elegans shows widespread transcriptional regulation of metabolic genes, coexpression of metabolic (sub)-pathways, and their activation/repression conditions. https://t.co/K0OuxK7CQ6
Two papers published today in @Nature describe a significant advance in understanding the complex functions of the metabolic network. Read about new research from the lab of Marian Walhout, PhD: https://t.co/LjHUFeCPFA
#metabolic#metabolism
Happy to share our back-to-back papers in @Nature, presenting a new framework for understanding metabolism - using genomics rather than traditional biochemistry! This led to a systems-level understanding of both metabolic wiring and rewiring. @UMassChan
https://t.co/xqUUkOriko
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Making Perturb-Seq easier and efficient by linear combinations and deconvolution of the genetic perturbations
Compressed Perturb-seq enables highly efficient genetic screens
https://t.co/EoDXuVoJxU
An age ‘clock’ based on some 200 proteins found in the blood can predict a person’s risk of developing 18 chronic illnesses, including heart disease, cancer, diabetes and Alzheimer’s disease https://t.co/kbBdufInaD
Stress leads to disarray of the gut microbiome, which in turn causes inflammation and a drop in the body’s ability to fend off infection https://t.co/63TlTLJTNY
Roundworms have short memories, forgetting new information just two to three hours after learning it.
But put them on ice and they don’t forget — until they are returned to room temperature https://t.co/qSBigYoJqF
Want to infer causal regulatory changes from scRNA-seq/spatial data? We combined Perturb-seq with @ParseBio + @UltimaGenomics to systematically perturb signaling regulators across six cell lines and learn their downstream targets. Preprint and data at https://t.co/SvPvNmOy3S
Microsoft Teams is an abomination of a product.
The only reason companies use it is because it's included with an Office 365 subscription.
I'm not convinced that even a single designer ever worked on it
Wondering how could you interpret the metabolic gene changes in your RNA-seq/proteomics data? Check out our new study on the relationship between enzyme levels and metabolic flux! A tweetorial to come!
https://t.co/Fa5jt0EIwr
Congrats, @seussofscience, for receiving the 2023 Chancellor's Award! We're so proud, Christine; well-deserved recognition of your embodiment of the ideals of a biomedical research scientist through outstanding doctoral research, leadership & service to @UMassChan Community! 🥳🥳